A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis
M Grewe, CAFM Bruijnzeel-Koomen, E Schöpf… - Immunology today, 1998 - cell.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intensely
pruritic subacute and chronic eczematous plaques, the pathogenesis of which appears to …
pruritic subacute and chronic eczematous plaques, the pathogenesis of which appears to …
[PDF][PDF] Adverse reactions to food.
C Bruijnzeel-Koomen, C Ortolani, K Aas… - Allergy, 1995 - researchgate.net
Adverse reactions to food are frequently suspected and are therefore routine work in daily
practice. However, in spite of this, our knowledge of the structure of food allergens and the …
practice. However, in spite of this, our knowledge of the structure of food allergens and the …
A consensus protocol for the determination of the threshold doses for allergenic foods: how much is too much?
SL Taylor, SL Hefle, C Bindslev‐jensen… - Clinical & …, 2004 - Wiley Online Library
Background While the ingestion of small amounts of an offending food can elicit adverse
reactions in individuals with IgE‐mediated food allergies, little information is known regarding …
reactions in individuals with IgE‐mediated food allergies, little information is known regarding …
Photosensitivity in patients with lupus erythematosus: a clinical and photobiological study of 100 patients using a prolonged phototest protocol
CJG Sanders, H Van Weelden… - British Journal of …, 2003 - academic.oup.com
Background There is a clear relationship between ultraviolet (UV) radiation (UVR) and the
clinical manifestations of patients with lupus erythematosus (LE). Cutaneous lesions are …
clinical manifestations of patients with lupus erythematosus (LE). Cutaneous lesions are …
Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis
FC Van Reijsen, C Bruijnzeel-Koomen… - Journal of allergy and …, 1992 - Elsevier
T-cell lines have been derived from aeroallergen-induced eczematous patch test sites of
patients with atopic dermatitis (AD). Biopsy specimens were obtained 24 hours after allergen …
patients with atopic dermatitis (AD). Biopsy specimens were obtained 24 hours after allergen …
Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: an immunocytochemical study
T Thepen, EG Langeveld-Wildschut, IC Bihari… - Journal of Allergy and …, 1996 - Elsevier
In the pathogenesis of atopic dermatitis (AD), IgE plays an important role; and T H2 cells,
producing IL-4, have been ascribed a key role in allergic diseases such as AD. To investigate …
producing IL-4, have been ascribed a key role in allergic diseases such as AD. To investigate …
Heat-induced conformational changes of Ara h 1, a major peanut allergen, do not affect its allergenic properties
SJ Koppelman, CAFM Bruijnzeel-Koomen… - Journal of Biological …, 1999 - ASBMB
Ara h 1, a major peanut allergen was isolated, and its structure on secondary, tertiary, and
quaternary level at ambient temperature was investigated using spectroscopic and …
quaternary level at ambient temperature was investigated using spectroscopic and …
Anti‐IL‐5 recombinant humanized monoclonal antibody (mepolizumab) for the treatment of atopic dermatitis
JM Oldhoff, U Darsow, T Werfel, K Katzer, A Wulf… - Allergy, 2005 - Wiley Online Library
Background: Eosinophils may play an important role in the pathogenesis of atopic dermatitis
(AD). Interleukin‐5 is essential for eosinophil growth, differentiation and migration. A …
(AD). Interleukin‐5 is essential for eosinophil growth, differentiation and migration. A …
[HTML][HTML] CD8+ T cells in the lesional skin of atopic dermatitis and psoriasis patients are an important source of IFN-γ, IL-13, IL-17, and IL-22
Although CD4 + T cells are known to contribute to the pathology of atopic dermatitis (AD)
and psoriasis, the role of CD8 + T cells in these diseases remains poorly characterized. The …
and psoriasis, the role of CD8 + T cells in these diseases remains poorly characterized. The …
Quantification of major peanut allergens Ara h 1 and Ara h 2 in the peanut varieties Runner, Spanish, Virginia, and Valencia, bred in different parts of the world
SJ Koppelman, RAA Vlooswijk, LMJ Knippels… - Allergy, 2001 - Wiley Online Library
Background: The serology of peanut allergy seems to be different in various parts of the
world. We analyzed the composition of 13 samples of three varieties of peanut in order to …
world. We analyzed the composition of 13 samples of three varieties of peanut in order to …