Biological activity of organotin compounds—an overview
NJ Snoeij, AH Penninks, W Seinen - Environmental research, 1987 - Elsevier
As a consequence of the rapid expansion of the uses and applications of the organotin
compounds, the concern about their environmental and health effects is increasing. The main …
compounds, the concern about their environmental and health effects is increasing. The main …
THE PHARMACOKINETICS OF GLYCYRRHIZIC ACID EVALUATED BY PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING†
B Ploeger, T Mensinga, A Sips, W Seinen… - Drug metabolism …, 2001 - Taylor & Francis
Glycyrrhizic acid is widely applied as a sweetener in food products and chewing tobacco. In
addition, it is of clinical interest for possible treatment of chronic hepatitis C. In some highly …
addition, it is of clinical interest for possible treatment of chronic hepatitis C. In some highly …
Endotoxin release in cardiac surgery with cardiopulmonary bypass: pathophysiology and possible therapeutic strategies. An update
S Kats, JPAM Schönberger, R Brands… - European journal of …, 2011 - academic.oup.com
Cardiac surgery with cardiopulmonary bypass provokes a systemic inflammatory response
syndrome caused by the surgical trauma itself, blood contact with the non-physiological …
syndrome caused by the surgical trauma itself, blood contact with the non-physiological …
Determination of octanol/water partition coefficients for hydrophobic organic chemicals with the “slow‐stirring” method
J De Bruijn, F Busser, W Seinen… - … and Chemistry: An …, 1989 - Wiley Online Library
Experimental data are presented on octanol/water partition coefficients for 70 hydrophobic
organic chemicals that were determined with a “slow‐stirring” method. With this method, log K …
organic chemicals that were determined with a “slow‐stirring” method. With this method, log K …
2-Chloro-s-Triazine Herbicides Induce Aromatase (CYP19) Activity in H295R Human Adrenocortical Carcinoma Cells: A Novel Mechanism for Estrogenicity?
JT Sanderson, W Seinen, JP Giesy… - Toxicological …, 2000 - academic.oup.com
There is increasing concern that certain chemicals in the environment can cause endocrine
disruption in exposed humans and wildlife. Investigations of potential effects on endocrine …
disruption in exposed humans and wildlife. Investigations of potential effects on endocrine …
Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays
RHMM Schreurs, E Sonneveld, JHJ Jansen… - Toxicological …, 2005 - academic.oup.com
Two important ingredients of personal care products, namely polycyclic musk fragrances
and UV filters, can be found in the environment and in humans. In previous studies, several …
and UV filters, can be found in the environment and in humans. In previous studies, several …
Tetracyclines and tetracycline resistance in agricultural soils: microcosm and field studies
H Schmitt, K Stoob, G Hamscher, E Smit, W Seinen - Microbial ecology, 2006 - Springer
The influence of the use of antibiotics on the prevalence of resistance genes in the
environment is still poorly understood. We studied the diversity of tetracycline and sulfonamide …
environment is still poorly understood. We studied the diversity of tetracycline and sulfonamide …
Calf intestinal alkaline phosphatase, a novel therapeutic drug for lipopolysaccharide (LPS)-mediated diseases, attenuates LPS toxicity in mice and piglets
C Beumer, M Wulferink, W Raaben, D Fiechter… - … of Pharmacology and …, 2003 - ASPET
It has been demonstrated that human placental alkaline phosphatase (HPLAP) attenuates
the lipopolysaccharide (LPS)-mediated inflammatory response, likely through …
the lipopolysaccharide (LPS)-mediated inflammatory response, likely through …
Measurement of the free concentration using solid-phase microextraction: Binding to protein
WHJ Vaes, E Urrestarazu Ramos… - Analytical …, 1996 - ACS Publications
A method is described to measure freely dissolved compounds, using solid-phase microextraction
(SPME) as sampling technique. Currently applied techniques, like solvent extraction, …
(SPME) as sampling technique. Currently applied techniques, like solvent extraction, …
Measured pore-water concentrations make equilibrium partitioning work a data analysis
R Kraaij, P Mayer, FJM Busser… - … science & technology, 2003 - ACS Publications
There is an increasing body of evidence that the bioaccumulation of sediment-associated
hydrophobic organic compounds (HOCs) is strongly influenced by sequestration. At present, it …
hydrophobic organic compounds (HOCs) is strongly influenced by sequestration. At present, it …