Consensus statement: chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies DT Miller, MP Adam, S Aradhya, LG Biesecker, AR Brothman, NP Carter, ... The American Journal of Human Genetics 86 (5), 749-764, 2010 | 3117 | 2010 |
Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer K Kok, J Osinga, B Carritt, MB Davis, AH van der Hout, AY van der Veen, ... Nature 330 (6148), 578-581, 1987 | 476 | 1987 |
Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes K Kok, SL Naylor, CHCM Buys Advances in cancer research 71, 27-92, 1997 | 444 | 1997 |
Histone Methyltransferase Gene SETD2 Is a Novel Tumor Suppressor Gene in Clear Cell Renal Cell Carcinoma G Duns, E van den Berg, I van Duivenbode, J Osinga, H Hollema, ... Cancer research 70 (11), 4287-4291, 2010 | 284 | 2010 |
p53 Mutations in Human Lung Tumors CW Miller, K Simon, A Aslo, K Kok, J Yokota, CHCM Buys, M Terada, ... Cancer research 52 (7), 1695-1698, 1992 | 252 | 1992 |
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure CT Storlazzi, A Lonoce, MC Guastadisegni, D Trombetta, P D'Addabbo, ... Genome research 20 (9), 1198-1206, 2010 | 237 | 2010 |
Nine patients with a microdeletion 15q11. 2 between breakpoints 1 and 2 of the Prader–Willi critical region, possibly associated with behavioural disturbances M Doornbos, B Sikkema-Raddatz, CAL Ruijvenkamp, T Dijkhuizen, ... European journal of medical genetics 52 (2-3), 108-115, 2009 | 194 | 2009 |
Isolation of the human semaphorin III/F gene (SEMA3F) at chromosome 3p21, a region deleted in lung cancer RH Xiang, CH Hensel, DK Garcia, HC Carlson, K Kok, MC Daly, ... Genomics 32 (1), 39-48, 1996 | 178 | 1996 |
SETD2: an epigenetic modifier with tumor suppressor functionality J Li, G Duns, H Westers, R Sijmons, A van den Berg, K Kok Oncotarget 7 (31), 50719, 2016 | 159 | 2016 |
Genotype–phenotype correlation in 21 patients with Wolf–Hirschhorn syndrome using high resolution array comparative genome hybridisation (CGH) NMC Maas, G Van Buggenhout, F Hannes, B Thienpont, D Sanlaville, ... Journal of medical genetics 45 (2), 71-80, 2008 | 158 | 2008 |
A high throughput experimental approach to identify miRNA targets in human cells LP Tan, E Seinen, G Duns, D de Jong, OCM Sibon, S Poppema, ... Nucleic acids research 37 (20), e137-e137, 2009 | 150 | 2009 |
A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme. K Kok, R Hofstra, A Pilz, A van den Berg, P Terpstra, CH Buys, B Carritt Proceedings of the National Academy of Sciences 90 (13), 6071-6075, 1993 | 115 | 1993 |
A homozygous deletion in a small cell lung cancer cell line involving a 3p21 region with a marked instability in yeast artificial chromosomes K Kok, A van den Berg, PMJF Veldhuis, AY van der Veen, M Franke, ... Cancer research 54 (15), 4183-4187, 1994 | 107 | 1994 |
Genome‐wide arrays: Quality criteria and platforms to be used in routine diagnostics JR Vermeesch, PD Brady, D Sanlaville, K Kok, RJ Hastings Human mutation 33 (6), 906-915, 2012 | 105 | 2012 |
Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer A L'Abbate, G Macchia, P D'Addabbo, A Lonoce, D Tolomeo, D Trombetta, ... Nucleic acids research 42 (14), 9131-9145, 2014 | 104 | 2014 |
The mutational landscape of Hodgkin lymphoma cell lines determined by whole-exome sequencing Y Liu, FR Abdul Razak, M Terpstra, FC Chan, A Saber, M Nijland, ... Leukemia 28 (11), 2248-2251, 2014 | 103 | 2014 |
Towards sustained silencing of HER2/neu in cancer by epigenetic editing F Falahi, C Huisman, HG Kazemier, P van der Vlies, K Kok, GAP Hospers, ... Molecular Cancer Research 11 (9), 1029-1039, 2013 | 97 | 2013 |
Amplicon mapping and expression profiling identify the Fas-associated death domain gene as a new driver in the 11q13. 3 amplicon in laryngeal/pharyngeal cancer JH Gibcus, L Menkema, MF Mastik, MA Hermsen, GH de Bock, ... Clinical cancer research 13 (21), 6257-6266, 2007 | 96 | 2007 |
Targeted exome sequencing in clear cell renal cell carcinoma tumors suggests aberrant chromatin regulation as a crucial step in ccRCC development G Duns, RMW Hofstra, JG Sietzema, H Hollema, I van Duivenbode, ... Human mutation 33 (7), 1059-1062, 2012 | 95 | 2012 |
MiRNA profiling in B non-Hodgkin lymphoma: a MYC-related miRNA profile characterizes Burkitt lymphoma JL Robertus, J Kluiver, C Weggemans, G Harms, RM Reijmers, Y Swart, ... British journal of haematology 149 (6), 896-899, 2010 | 94 | 2010 |