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Richard Meek
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Nonmedical uses of antibiotics: time to restrict their use?
RW Meek, H Vyas, LJV Piddock
PLoS biology 13 (10), e1002266, 2015
1802015
HIV drugs inhibit transfer of plasmids carrying extended-spectrum β-lactamase and carbapenemase genes
MMC Buckner, ML Ciusa, RW Meek, AR Moorey, GE McCallum, ...
Mbio 11 (1), 10.1128/mbio. 03355-19, 2020
272020
A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High‐Throughput Screening: Application to O‐GlcNAc Transferase
MG Alteen, C Gros, RW Meek, DA Cardoso, JA Busmann, G Sangouard, ...
Angewandte Chemie International Edition 59 (24), 9601-9609, 2020
252020
Cryo-EM structure provides insights into the dimer arrangement of the O-linked β-N-acetylglucosamine transferase OGT
RW Meek, JN Blaza, JA Busmann, MG Alteen, DJ Vocadlo, GJ Davies
Nature communications 12 (1), 6508, 2021
242021
Structural basis for activation of a diguanylate cyclase required for bacterial predation in Bdellovibrio
RW Meek, IT Cadby, PJ Moynihan, AL Lovering
Nature communications 10 (1), 4086, 2019
242019
Potent De Novo Macrocyclic Peptides That Inhibit O‐GlcNAc Transferase through an Allosteric Mechanism
MG Alteen, H Peacock, RW Meek, JA Busmann, S Zhu, GJ Davies, ...
Angewandte Chemie 135 (5), e202215671, 2023
122023
Nucleotide signaling pathway convergence in a cAMP‐sensing bacterial c‐di‐GMP phosphodiesterase
IT Cadby, SM Basford, R Nottingham, R Meek, R Lowry, C Lambert, ...
The EMBO journal 38 (17), e100772, 2019
122019
Structure-function characterization of the conserved regulatory mechanism of the Escherichia coli M48 metalloprotease BepA
JA Bryant, IT Cadby, ZS Chong, G Boelter, YR Sevastsyanovich, ...
Journal of Bacteriology 203 (2), 10.1128/jb. 00434-20, 2020
102020
Cryo-EM structures of human fucosidase FucA1 reveal insight into substrate recognition and catalysis
Z Armstrong, RW Meek, L Wu, JN Blaza, GJ Davies
Structure 30 (10), 1443-1451. e5, 2022
82022
The primary familial brain calcification-associated protein MYORG is an α-galactosidase with restricted substrate specificity
RW Meek, J Brockerman, OB Fordwour, WF Zandberg, GJ Davies, ...
PLoS biology 20 (9), e3001764, 2022
72022
Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase
MG Alteen, RW Meek, S Kolappan, JA Busmann, J Cao, Z O’Gara, ...
Proceedings of the National Academy of Sciences 120 (42), e2303690120, 2023
42023
Structure-function analysis of the Escherichia coli β–barrel assembly enhancing protease BepA suggests a role for a self-inhibitory state
JA Bryant, IT Cadby, ZS Chong, YR Sevastsyanovich, FC Morris, ...
bioRxiv, 689117, 2019
32019
Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum
SJ Williams, J Li, M Sharma, RW Meek, A Alhifthi, Z Armstrong, NM Soler, ...
Chemical Science, 2023
22023
Bdellovibrio bacteriovorus phosphoglucose isomerase structures reveal novel rigidity in the active site of a selected subset of enzymes upon substrate binding
RW Meek, IT Cadby, AL Lovering
Open Biology 11 (8), 210098, 2021
12021
Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum
J Li, M Sharma, R Meek, A Alhifthi, Z Armstrong, NM Soler, M Lee, ...
bioRxiv, 2023.03. 13.532361, 2023
2023
Structures of Bdellovibrio bacteriovorus phosphoglucose isomerase reveal novel rigidity in the active site of a selected subset of enzymes upon substrate binding
RW Meek, IT Cadby, AL Lovering
bioRxiv, 2021.03. 26.437203, 2021
2021
Structural and functional analysis of proteins involved in the C-DI-GMP network of the predatory bacterium\(Bdellovibrio\)\(bacteriovirus\)
RW Meek
University of Birmingham, 2018
2018
FULL REPORT Non-medical uses of antibacterial compounds (antibiotics): time to restrict their use?
RW Meek, H Vyas, LJV Piddock
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Articles 1–18