Nonmedical uses of antibiotics: time to restrict their use? RW Meek, H Vyas, LJV Piddock PLoS biology 13 (10), e1002266, 2015 | 180 | 2015 |
HIV drugs inhibit transfer of plasmids carrying extended-spectrum β-lactamase and carbapenemase genes MMC Buckner, ML Ciusa, RW Meek, AR Moorey, GE McCallum, ... Mbio 11 (1), 10.1128/mbio. 03355-19, 2020 | 27 | 2020 |
A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High‐Throughput Screening: Application to O‐GlcNAc Transferase MG Alteen, C Gros, RW Meek, DA Cardoso, JA Busmann, G Sangouard, ... Angewandte Chemie International Edition 59 (24), 9601-9609, 2020 | 25 | 2020 |
Cryo-EM structure provides insights into the dimer arrangement of the O-linked β-N-acetylglucosamine transferase OGT RW Meek, JN Blaza, JA Busmann, MG Alteen, DJ Vocadlo, GJ Davies Nature communications 12 (1), 6508, 2021 | 24 | 2021 |
Structural basis for activation of a diguanylate cyclase required for bacterial predation in Bdellovibrio RW Meek, IT Cadby, PJ Moynihan, AL Lovering Nature communications 10 (1), 4086, 2019 | 24 | 2019 |
Potent De Novo Macrocyclic Peptides That Inhibit O‐GlcNAc Transferase through an Allosteric Mechanism MG Alteen, H Peacock, RW Meek, JA Busmann, S Zhu, GJ Davies, ... Angewandte Chemie 135 (5), e202215671, 2023 | 12 | 2023 |
Nucleotide signaling pathway convergence in a cAMP‐sensing bacterial c‐di‐GMP phosphodiesterase IT Cadby, SM Basford, R Nottingham, R Meek, R Lowry, C Lambert, ... The EMBO journal 38 (17), e100772, 2019 | 12 | 2019 |
Structure-function characterization of the conserved regulatory mechanism of the Escherichia coli M48 metalloprotease BepA JA Bryant, IT Cadby, ZS Chong, G Boelter, YR Sevastsyanovich, ... Journal of Bacteriology 203 (2), 10.1128/jb. 00434-20, 2020 | 10 | 2020 |
Cryo-EM structures of human fucosidase FucA1 reveal insight into substrate recognition and catalysis Z Armstrong, RW Meek, L Wu, JN Blaza, GJ Davies Structure 30 (10), 1443-1451. e5, 2022 | 8 | 2022 |
The primary familial brain calcification-associated protein MYORG is an α-galactosidase with restricted substrate specificity RW Meek, J Brockerman, OB Fordwour, WF Zandberg, GJ Davies, ... PLoS biology 20 (9), e3001764, 2022 | 7 | 2022 |
Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase MG Alteen, RW Meek, S Kolappan, JA Busmann, J Cao, Z O’Gara, ... Proceedings of the National Academy of Sciences 120 (42), e2303690120, 2023 | 4 | 2023 |
Structure-function analysis of the Escherichia coli β–barrel assembly enhancing protease BepA suggests a role for a self-inhibitory state JA Bryant, IT Cadby, ZS Chong, YR Sevastsyanovich, FC Morris, ... bioRxiv, 689117, 2019 | 3 | 2019 |
Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum SJ Williams, J Li, M Sharma, RW Meek, A Alhifthi, Z Armstrong, NM Soler, ... Chemical Science, 2023 | 2 | 2023 |
Bdellovibrio bacteriovorus phosphoglucose isomerase structures reveal novel rigidity in the active site of a selected subset of enzymes upon substrate binding RW Meek, IT Cadby, AL Lovering Open Biology 11 (8), 210098, 2021 | 1 | 2021 |
Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum J Li, M Sharma, R Meek, A Alhifthi, Z Armstrong, NM Soler, M Lee, ... bioRxiv, 2023.03. 13.532361, 2023 | | 2023 |
Structures of Bdellovibrio bacteriovorus phosphoglucose isomerase reveal novel rigidity in the active site of a selected subset of enzymes upon substrate binding RW Meek, IT Cadby, AL Lovering bioRxiv, 2021.03. 26.437203, 2021 | | 2021 |
Structural and functional analysis of proteins involved in the C-DI-GMP network of the predatory bacterium\(Bdellovibrio\)\(bacteriovirus\) RW Meek University of Birmingham, 2018 | | 2018 |
FULL REPORT Non-medical uses of antibacterial compounds (antibiotics): time to restrict their use? RW Meek, H Vyas, LJV Piddock | | |