Peter W. Schiller
Peter W. Schiller
Research Professor, Clinical Res. Inst..Montreal and Research Prof. Pharmacol., Univ. of Montreal
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Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury
K Zhao, GM Zhao, D Wu, Y Soong, AV Birk, PW Schiller, HH Szeto
Journal of Biological Chemistry 279 (33), 34682-34690, 2004
Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta†…
PW Schiller, TM Nguyen, G Weltrowska, BC Wilkes, BJ Marsden, ...
Proceedings of the National Academy of Sciences 89 (24), 11871-11875, 1992
Synthesis and pharmacological characterization in vitro of cyclic enkephalin analogs: effect of conformational constraints on opiate receptor selectivity
J DiMaio, TMD Nguyen, C Lemieux, PW Schiller
Journal of medicinal chemistry 25 (12), 1432-1438, 1982
Localization of immunoreactive synthetic atrial natriuretic factor (ANF) in the heart of various animal species.
C Chapeau, J Gutkowska, PW Schiller, RW Milne, G Thibault, R Garcia, ...
Journal of histochemistry & cytochemistry 33 (6), 541-550, 1985
Characterization of specific receptors for atrial natriuretic factor in bovine adrenal zona glomerulosa
A De Lean, J Gutkowska, N McNicoll, PW Schiller, M Cantin, J Genest
Life sciences 35 (23), 2311-2318, 1984
An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library
CT Dooley, NN Chung, BC Wilkes, PW Schiller, JM Bidlack, ...
Science 266 (5193), 2019-2022, 1994
MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1
H Zhu, Y Yang, Y Wang, J Li, PW Schiller, T Peng
Cardiovascular research 92 (1), 75-84, 2011
The opioid μ agonist/δ antagonist DIPP-NH2 [Ψ] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in rats
PW Schiller, ME Fundytus, L Merovitz, G Weltrowska, TMD Nguyen, ...
Journal of medicinal chemistry 42 (18), 3520-3526, 1999
A genetically encoded biosensor reveals location bias of opioid drug action
M Stoeber, D Julliť, BT Lobingier, T Laeremans, J Steyaert, PW Schiller, ...
Neuron 98 (5), 963-976. e5, 2018
Synthesis and in vitro opioid activity profiles of DALDA analogues
PW Schiller, TMD Nguyen, I Berezowska, S Dupuis, G Weltrowska, ...
European journal of medicinal chemistry 35 (10), 895-901, 2000
Dermorphin analogs carrying an increased positive net charge in their" message" domain display extremely high. mu.-opioid receptor selectivity
PW Schiller, NTM Dung, NN Chung, C Lemieux
Journal of medicinal chemistry 32 (3), 698-703, 1989
Transcellular transport of a highly polar 3+ net charge opioid tetrapeptide
K Zhao, G Luo, GM Zhao, PW Schiller, HH Szeto
Journal of Pharmacology and Experimental Therapeutics 304 (1), 425-432, 2003
Bi-or multifunctional opioid peptide drugs
PW Schiller
Life sciences 86 (15-16), 598-603, 2010
TIPP [. psi.]: a highly potent and stable pseudopeptide. delta. opioid receptor antagonist with extraordinary. delta. selectivity
PW Schiller, G Weltrowska, TMD Nguyen, BC Wilkes, NN Chung, ...
Journal of medicinal chemistry 36 (21), 3182-3187, 1993
A cyclic enkephalin analog with high in vitro opiate activity.
J DiMaio, PW Schiller
Proceedings of the National Academy of Sciences 77 (12), 7162-7166, 1980
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
G Fenalti, NA Zatsepin, C Betti, P Giguere, GW Han, A Ishchenko, W Liu, ...
Nature structural & molecular biology 22 (3), 265-268, 2015
Novel therapies targeting inner mitochondrial membrane—from discovery to clinical development
HH Szeto, PW Schiller
Pharmaceutical research 28 (11), 2669-2679, 2011
Attenuation of morphine tolerance and dependence with the highly selective δ-opioid receptor antagonist TIPP [ψ]
ME Fundytus, PW Schiller, M Shapiro, G Weltrowska, TJ Coderre
European journal of pharmacology 286 (1), 105-108, 1995
Unsulfated C-terminal 7-peptide of cholecystokinin: a new ligand of the opiate receptor
PW Schiller, A Lipton, DF Horrobin, M Bodanszky
Biochemical and biophysical research communications 85 (4), 1332-1338, 1978
The TIPP opioid peptide family: development of δ antagonists, δ agonists, and mixed μ agonist/δ antagonists
PW Schiller, G Weltrowska, I Berezowska, TMD Nguyen, BC Wilkes, ...
Peptide Science 51 (6), 411-425, 1999
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