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Sheraz Gul
Sheraz Gul
Head of Assay Development and Drug Repurposing
Verified email at itmp.fraunhofer.de
Title
Cited by
Cited by
Year
Specificity Determinants of Recruitment Peptides Bound to Phospho-CDK2/Cyclin A,
ED Lowe, I Tews, KY Cheng, NR Brown, S Gul, MEM Noble, SJ Gamblin, ...
Biochemistry 41 (52), 15625-15634, 2002
2062002
A classical enzyme active center motif lacks catalytic competence until modulated electrostatically
S Pinitglang, AB Watts, M Patel, JD Reid, MA Noble, S Gul, A Bokth, ...
Biochemistry 36 (33), 9968-9982, 1997
1221997
Identification of small-molecule frequent hitters from AlphaScreen high-throughput screens
K Schorpp, I Rothenaigner, E Salmina, J Reinshagen, T Low, JK Brenke, ...
Journal of biomolecular screening 19 (5), 715-726, 2014
1032014
Bone marrow mononuclear cells activate angiogenesis via gap junction–mediated cell-cell interaction
A Kikuchi-Taura, Y Okinaka, Y Takeuchi, Y Ogawa, M Maeda, Y Kataoka, ...
Stroke 51 (4), 1279-1289, 2020
632020
Characteristics of the cancer stem cell niche and therapeutic strategies
F Ju, MM Atyah, N Horstmann, S Gul, R Vago, CJ Bruns, Y Zhao, QZ Dong, ...
Stem Cell Research & Therapy 13 (1), 233, 2022
542022
Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs
C Borsari, R Luciani, C Pozzi, I Poehner, S Henrich, M Trande, ...
Journal of medicinal chemistry 59 (16), 7598-7616, 2016
502016
A bioluminogenic HDAC activity assay: validation and screening
F Halley, J Reinshagen, B Ellinger, M Wolf, AL Niles, NJ Evans, ...
Journal of biomolecular screening 16 (10), 1227-1235, 2011
492011
Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity
F Di Pisa, G Landi, L Dello Iacono, C Pozzi, C Borsari, S Ferrari, ...
Molecules 22 (3), 426, 2017
472017
Protein–protein interaction modulator drug discovery: past efforts and future opportunities using a rich source of low-and high-throughput screening assays
S Gul, K Hadian
Expert Opinion on Drug Discovery 9 (12), 1393-1404, 2014
442014
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections
P Linciano, CB Moraes, LM Alcantara, CH Franco, B Pascoalino, ...
European Journal of Medicinal Chemistry 146, 423-434, 2018
372018
Ionization characteristics and chemical influences of aspartic acid residue 158 of papain and caricain determined by structure-related kinetic and computational techniques …
MA NOBLE, S GUL, CS VERMA, K BROCKLEHURST
Biochemical Journal 351 (3), 723-733, 2000
362000
Tegaserod mimics the neurostimulatory glycan polysialic acid and promotes nervous system repair
J Bushman, B Mishra, M Ezra, S Gul, C Schulze, S Chaudhury, D Ripoll, ...
Neuropharmacology 79, 456-466, 2014
352014
Epigenetic assays for chemical biology and drug discovery
S Gul
Clinical epigenetics 9 (1), 41, 2017
342017
Generation of nucleophilic character in the Cys25/His159 ion pair of papain involves Trp177 but not Asp158
S Gul, S Hussain, MP Thomas, M Resmini, CS Verma, EW Thomas, ...
Biochemistry 47 (7), 2025-2035, 2008
342008
The target residence time of antihistamines determines their antagonism of the G protein-coupled histamine H1 receptor
R Bosma, G Witt, LAI Vaas, I Josimovic, P Gribbon, HF Vischer, S Gul, ...
Frontiers in Pharmacology 8, 667, 2017
332017
Enzyme Assays
S Gul, SK Sreedharan, K Brocklehurst
Book Reviews 27, 60-66, 1999
331999
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display …
E Uliassi, G Fiorani, RL Krauth-Siegel, C Bergamini, R Fato, G Bianchini, ...
European Journal of Medicinal Chemistry 141, 138-148, 2017
322017
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
P Linciano, A Dawson, I Pöhner, DM Costa, MS Sa, A Cordeiro-da-Silva, ...
ACS omega 2 (9), 5666-5683, 2017
302017
Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture
G Loers, V Saini, B Mishra, F Papastefanaki, D Lutz, S Chaudhury, ...
Journal of neurochemistry 128 (1), 88-100, 2014
282014
Exemplification of the challenges associated with utilising fluorescence intensity based assays in discovery
S Gul, P Gribbon
Expert Opinion on Drug Discovery 5 (7), 681-690, 2010
282010
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Articles 1–20