Biphasic regulation of NF-κB activity underlies the pro-and anti-inflammatory actions of nitric oxide L Connelly, M Palacios-Callender, C Ameixa, S Moncada, AJ Hobbs The Journal of Immunology 166 (6), 3873-3881, 2001 | 449 | 2001 |
Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression L Connelly, AT Jacobs, M Palacios-Callender, S Moncada, AJ Hobbs Journal of Biological Chemistry 278 (29), 26480-26487, 2003 | 227 | 2003 |
The nuclear factor-κB pathway controls the progression of prostate cancer to androgen-independent growth RJ Jin, Y Lho, L Connelly, Y Wang, X Yu, L Saint Jean, TC Case, ... Cancer research 68 (16), 6762-6769, 2008 | 224 | 2008 |
Epithelial NF-κB activation promotes urethane-induced lung carcinogenesis GT Stathopoulos, TP Sherrill, DS Cheng, RM Scoggins, W Han, ... Proceedings of the National Academy of Sciences 104 (47), 18514-18519, 2007 | 216 | 2007 |
Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice a pro-inflammatory role for enos-derived no in vivo L Connelly, M Madhani, AJ Hobbs Journal of Biological Chemistry 280 (11), 10040-10046, 2005 | 193 | 2005 |
Interleukin-5 Facilitates Lung Metastasis by Modulating the Immune MicroenvironmentIL5 Facilitates Lung Metastasis R Zaynagetdinov, TP Sherrill, LA Gleaves, AG McLoed, JA Saxon, ... Cancer research 75 (8), 1624-1634, 2015 | 129 | 2015 |
Silent information regulator (Sir) T1 inhibits NF‐κB signaling to maintain normal skeletal remodeling JR Edwards, DS Perrien, N Fleming, JS Nyman, K Ono, L Connelly, ... Journal of Bone and Mineral Research 28 (4), 960-969, 2013 | 122 | 2013 |
Inhibition of NF-kappa B activity in mammary epithelium increases tumor latency and decreases tumor burden L Connelly, W Barham, HM Onishko, T Sherrill, LA Chodosh, TS Blackwell, ... Oncogene 30 (12), 1402-1412, 2011 | 117 | 2011 |
Tracazolate reveals a novel type of allosteric interaction with recombinant γ-aminobutyric acidA receptors SA Thompson, PB Wingrove, L Connelly, PJ Whiting, KA Wafford Molecular pharmacology 61 (4), 861-869, 2002 | 87 | 2002 |
NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model L Connelly, W Barham, HM Onishko, L Chen, TP Sherrill, T Zabuawala, ... Breast cancer research 13 (4), 1-14, 2011 | 77 | 2011 |
Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection L Connelly, W Barham, R Pigg, L Saint‐Jean, T Sherrill, DS Cheng, ... Journal of cellular physiology 222 (1), 73-81, 2010 | 74 | 2010 |
A transgenic model reveals important roles for the NF-κB alternative pathway (p100/p52) in mammary development and links to tumorigenesis L Connelly, C Robinson-Benion, M Chont, L Saint-Jean, H Li, ... Journal of Biological Chemistry 282 (13), 10028-10035, 2007 | 69 | 2007 |
Osteoprotegerin in breast cancer: beyond bone remodeling M Weichhaus, STM Chung, L Connelly Molecular cancer 14 (1), 1-7, 2015 | 64 | 2015 |
Epithelial nuclear factor-κB signaling promotes lung carcinogenesis via recruitment of regulatory T lymphocytes R Zaynagetdinov, GT Stathopoulos, TP Sherrill, DS Cheng, AG McLoed, ... Oncogene 31 (26), 3164-3176, 2012 | 64 | 2012 |
Targeted therapy for breast cancer: An overview of drug classes and outcomes AT Jacobs, DM Castaneda-Cruz, MM Rose, L Connelly Biochemical Pharmacology, 115209, 2022 | 49 | 2022 |
Osteoprotegerin expression in triple‐negative breast cancer cells promotes metastasis M Weichhaus, P Segaran, A Renaud, D Geerts, L Connelly Cancer medicine 3 (5), 1112-1125, 2014 | 41 | 2014 |
Osteoprotegerin mediates tumor-promoting effects of Interleukin-1beta in breast cancer cells STM Chung, D Geerts, K Roseman, A Renaud, L Connelly Molecular cancer 16 (1), 1-14, 2017 | 36 | 2017 |
Osteoprotegerin: Relationship to breast cancer risk and prognosis D Geerts, C Chopra, L Connelly Frontiers in Oncology 10, 462, 2020 | 21 | 2020 |
Intraductal injection of LPS as a mouse model of mastitis: signaling visualized via an NF-κB reporter transgenic W Barham, T Sherrill, L Connelly, TS Blackwell, FE Yull JoVE (Journal of Visualized Experiments), e4030, 2012 | 18 | 2012 |
Breast adipocyte co-culture increases the expression of pro-angiogenic factors in macrophages NVS Yadav, A Barcikowski, Y Uehana, AT Jacobs, L Connelly Frontiers in Oncology 10, 454, 2020 | 16 | 2020 |