| Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review C Stillhart, K Vučićević, P Augustijns, AW Basit, H Batchelor, TR Flanagan, ... European Journal of Pharmaceutical Sciences 147, 105280, 2020 | 181 | 2020 |
| Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4 AAK El-Sheikh, R Greupink, HM Wortelboer, JJMW Van Den Heuvel, ... Translational research 162 (6), 398-409, 2013 | 78 | 2013 |
| The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo R Greupink, HI Bakker, W Bouma, C Reker-Smit, DKF Meijer, L Beljaars, ... Journal of Pharmacology and Experimental Therapeutics 317 (2), 514-521, 2006 | 78 | 2006 |
| Drug dosing in pregnant women: challenges and opportunities in using physiologically based pharmacokinetic modeling and simulations AB Ke, R Greupink, K Abduljalil CPT: pharmacometrics & systems pharmacology 7 (2), 103-110, 2018 | 69 | 2018 |
| Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1 E van de Steeg, R Greupink, M Schreurs, IHG Nooijen, KCM Verhoeckx, ... Drug Metabolism and Disposition 41 (3), 592-601, 2013 | 66 | 2013 |
| Selective targeting of pentoxifylline to hepatic stellate cells using a novel platinum-based linker technology T Gonzalo, EG Talman, A van de Ven, K Temming, R Greupink, L Beljaars, ... Journal of Controlled Release 111 (1-2), 193-203, 2006 | 65 | 2006 |
| Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell R Greupink, HI Bakker, C Reker-Smit, RJ Kok, DKF Meijer, L Beljaars, ... Journal of hepatology 43 (5), 884-892, 2005 | 65 | 2005 |
| Interaction of fluvastatin with the liver-specific Na+-dependent taurocholate cotransporting polypeptide (NTCP) R Greupink, L Dillen, M Monshouwer, MT Huisman, FGM Russel European journal of pharmaceutical sciences 44 (4), 487-496, 2011 | 58 | 2011 |
| Targeting 15d-Prostaglandin J2 to Hepatic Stellate Cells: Two Options Evaluated WI Hagens, A Mattos, R Greupink, A de Jager-Krikken, C Reker-Smit, ... Pharmaceutical research 24, 566-574, 2007 | 56 | 2007 |
| direct‐acting antivirals for the treatment of HCV during pregnancy and lactation‐implications for maternal dosing, foetal exposure, and safety for mother and child JJM Freriksen, M van Seyen, A Judd, DM Gibb, IJ Collins, R Greupink, ... Alimentary pharmacology & therapeutics 50 (7), 738-750, 2019 | 50 | 2019 |
| Prediction of fetal darunavir exposure by integrating human ex-vivo placental transfer and physiologically based pharmacokinetic modeling S Schalkwijk, AO Buaben, JJM Freriksen, AP Colbers, DM Burger, ... Clinical pharmacokinetics 57, 705-716, 2018 | 48 | 2018 |
| Physiologically based modelling of darunavir/ritonavir pharmacokinetics during pregnancy A Colbers, R Greupink, C Litjens, D Burger, FGM Russel Clinical pharmacokinetics 55, 381-396, 2016 | 47 | 2016 |
| Therapeutic effects of the mitochondrial ROS-redox modulator KH176 in a mammalian model of Leigh Disease R de Haas, D Das, A Garanto, HG Renkema, R Greupink, ... Scientific reports 7 (1), 11733, 2017 | 45 | 2017 |
| Pharmacological considerations on the use of antiretrovirals in pregnancy A Colbers, R Greupink, D Burger Current opinion in infectious diseases 26 (6), 575-588, 2013 | 44 | 2013 |
| Pharmacokinetics of HIV-integrase inhibitors during pregnancy: mechanisms, clinical implications and knowledge gaps R van der Galiën, R Ter Heine, R Greupink, SJ Schalkwijk, ... Clinical pharmacokinetics 58, 309-323, 2019 | 43 | 2019 |
| Placental transfer of the HIV integrase inhibitor dolutegravir in an ex vivo human cotyledon perfusion model S Schalkwijk, R Greupink, AP Colbers, AC Wouterse, VGM Verweij, ... Journal of Antimicrobial Chemotherapy 71 (2), 480-483, 2016 | 43 | 2016 |
| Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3 E Gozalpour, R Greupink, HM Wortelboer, A Bilos, M Schreurs, ... Molecular pharmaceutics 11 (6), 1844-1855, 2014 | 43 | 2014 |
| Mannose-6-phosphate/insulin-like growth factor-II receptors may represent a target for the selective delivery of mycophenolic acid to fibrogenic cells R Greupink, HI Bakker, H van Goor, MH de Borst, L Beljaars, K Poelstra Pharmaceutical research 23, 1827-1834, 2006 | 42 | 2006 |
| A randomized trial of distal diuretics versus dietary sodium restriction for hypertension in chronic kidney disease DM Bovée, WJ Visser, I Middel, A De Mik–van Egmond, R Greupink, ... Journal of the American Society of Nephrology 31 (3), 650-662, 2020 | 41 | 2020 |
| Potentials and limitations of the low-molecular-weight protein lysozyme as a carrier for renal drug targeting RFG Haverdings, M Haas, AR Greupink, PAM deVries, F Moolenaar, ... Renal failure 23 (3-4), 397-409, 2001 | 41 | 2001 |
