A limited number of double-strand DNA breaks is sufficient to delay cell cycle progression J van den Berg, A G. Manjón, K Kielbassa, FM Feringa, R Freire, ... Nucleic acids research 46 (19), 10132-10144, 2018 | 75 | 2018 |
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer S Prekovic, K Schuurman, I Mayayo-Peralta, AG Manjón, M Buijs, S Yavuz, ... Nature Communications 12 (1), 4360, 2021 | 38 | 2021 |
Predicting patient response with models trained on cell lines and patient-derived xenografts by nonlinear transfer learning SMC Mourragui, M Loog, DJ Vis, K Moore, AG Manjon, MA van de Wiel, ... Proceedings of the National Academy of Sciences 118 (49), e2106682118, 2021 | 24 | 2021 |
TUBB3 overexpression has a negligible effect on the sensitivity to taxol in cultured cell lines MA Tame, AG Manjón, D Belokhvostova, JA Raaijmakers, RH Medema Oncotarget 8 (42), 71536, 2017 | 21 | 2017 |
Double-strand break toxicity is chromatin context independent A Friskes, L Koob, L Krenning, TM Severson, ES Koeleman, X Vergara, ... Nucleic Acids Research 50 (17), 9930-9947, 2022 | 11 | 2022 |
DNA end-resection in highly accessible chromatin produces a toxic break J van den Berg, SEP Joosten, YS Kim, AG Manjón, L Krenning, L Koob, ... BioRxiv, 691857, 2019 | 9 | 2019 |
Perturbations in 3D genome organization can promote acquired drug resistance AG Manjón, SG Manzo, S Prekovic, L Potgeter, T van Schaik, NQ Liu, ... Cell Reports 42 (10), 2023 | 7 | 2023 |
Precise+ predicts drug response in patients by non-linear subspace-based transfer from cell lines and pdx models S Mourragui, M Loog, DJ Vis, K Moore, AG Manjon, MA van de Wiel, ... bioRxiv, 2020 | 7 | 2020 |
Unexpected gene activation following CRISPR‐Cas9‐mediated genome editing AG Manjón, S Linder, H Teunissen, A Friskes, W Zwart, E de Wit, ... EMBO reports 23 (2), e53902, 2022 | 6 | 2022 |
Predicting clinical drug response from model systems by non-linear subspace-based transfer learning S Mourragui, M Loog, DJ Vis, K Moore, AG Manjon, MA van de Wiel, ... bioRxiv, 2020.06. 29.177139, 2020 | 5 | 2020 |
Glucocorticoids regulate cancer cell dormancy S Prekovic, K Schuurman, AG Manjón, M Buijs, IM Peralta, ... bioRxiv, 750406, 2019 | 4 | 2019 |
Widespread chromatin context-dependencies of DNA double-strand break repair proteins X Vergara, AG Manjón, B Morris, R Schep, C Leemans, MA Sanders, ... bioRxiv, 2022.10. 07.511243, 2022 | 2 | 2022 |
Chapter 6: Uncovering the role of DDR factors on regulating repair pathway choice in the context of chromatin AG Manjón, X Vergara, B Morris, R Beijersbergen PhD thesis: Gene re-activation mechanisms in the context of acquired drug …, 0 | | |
Chapter 4: DNA damage-dependent chromatin dynamics as a potential cause of therapy resistance AG Manjón, S Manzo, T van Schaik, A Friskes, H Teunissen, D Hintzen, ... PhD thesis: Gene re-activation mechanisms in the context of acquired drug …, 0 | | |
Chapter 7: General Discussion AG Manjón, RH Medema PhD thesis: Gene re-activation mechanisms in the context of acquired drug …, 0 | | |
Chapter 2: TUBB3 overexpression has a negligible effect on the sensitivity to Taxol in cultured cell lines MA Tame, AG Manjón, D Belokhvostova, JA Raaijmakers, RH Medema PhD thesis: Gene re-activation mechanisms in the context of acquired drug …, 0 | | |