| The essential medicinal chemistry of curcumin: miniperspective KM Nelson, JL Dahlin, J Bisson, J Graham, GF Pauli, MA Walters Journal of medicinal chemistry 60 (5), 1620-1637, 2017 | 1767 | 2017 |
| Chemistry: Chemical con artists foil drug discovery J Baell, MA Walters Nature 513 (7519), 481-483, 2014 | 1131 | 2014 |
| The promise and peril of chemical probes CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ... Nature chemical biology 11 (8), 536-541, 2015 | 833 | 2015 |
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS JL Dahlin, JWM Nissink, JM Strasser, S Francis, LA Higgins, H Zhou, ... Journal of medicinal chemistry 58 (5), 2091-2113, 2015 | 357 | 2015 |
| Mitigating risk in academic preclinical drug discovery JL Dahlin, J Inglese, MA Walters Nature reviews Drug discovery 14 (4), 279-294, 2015 | 177 | 2015 |
| The essential roles of chemistry in high-throughput screening triage JL Dahlin, MA Walters Future medicinal chemistry 6 (11), 1265-1290, 2014 | 156 | 2014 |
| Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains TF Chou, SL Bulfer, CC Weihl, K Li, LG Lis, MA Walters, FJ Schoenen, ... Journal of molecular biology 426 (15), 2886-2899, 2014 | 121 | 2014 |
| The essential medicinal chemistry of cannabidiol (CBD) KM Nelson, J Bisson, G Singh, JG Graham, SN Chen, JB Friesen, ... Journal of medicinal chemistry 63 (21), 12137-12155, 2020 | 106 | 2020 |
| Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors JL Dahlin, KM Nelson, JM Strasser, D Barsyte-Lovejoy, MM Szewczyk, ... Nature communications 8 (1), 1-14, 2017 | 103 | 2017 |
| Synthetic studies of the cyclopropyl iminium ion rearrangement. 3. Application of the cyclopropyl acyliminium ion rearrangement to a concise and highly convergent synthesis of … RK Boeckman, SW Goldstein, MA Walters Journal of the American Chemical Society 110 (24), 8250-8252, 1988 | 88 | 1988 |
| How to triage PAINS-full research JL Dahlin, MA Walters Assay and drug development technologies 14 (3), 168-174, 2016 | 79 | 2016 |
| High-throughput screening identifies inhibitors of DUX4-induced myoblast toxicity D Bosnakovski, SH Choi, JM Strasser, EA Toso, MA Walters, M Kyba Skeletal muscle 4, 1-11, 2014 | 77 | 2014 |
| [1, 8] naphthyridin-2-ones and related compounds for the treatment of schizophrenia DS Johnson, JT Repine, AD White US Patent 7,160,888, 2007 | 63 | 2007 |
| [1, 8] naphthyridin-2-ones and related compounds for the treatment of schizophrenia DS Johnson, JT Repine, AD White US Patent 7,160,888, 2007 | 63 | 2007 |
| The future of drug repositioning: old drugs, new opportunities TL Doan, M Pollastri, MA Walters, GI Georg Annual reports in medicinal chemistry 46, 385-401, 2011 | 62 | 2011 |
| Assessing synthetic accessibility of chemical compounds using machine learning methods Y Podolyan, MA Walters, G Karypis Journal of chemical information and modeling 50 (6), 979-991, 2010 | 60 | 2010 |
| Recent advances in the synthesis of heterocycles via ring-closing metathesis MA Walters Progress in Heterocyclic Chemistry 15, 1-36, 2003 | 60* | 2003 |
| GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity D Menon, A Innes, AJ Oakley, JE Dahlstrom, LM Jensen, A Brüstle, ... Scientific reports 7 (1), 17832, 2017 | 51 | 2017 |
| Cycloaddition reactions of a nitrogen-substituted oxyallyl cation with cyclopentadiene and substituted furans. Reaction conditions, diastereoselectivity, regioselectivity, and … MA Walters, HR Arcand The Journal of Organic Chemistry 61 (4), 1478-1486, 1996 | 51 | 1996 |
| A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death D Bosnakovski, MT da Silva, ST Sunny, ET Ener, EA Toso, C Yuan, Z Cui, ... Science advances 5 (9), eaaw7781, 2019 | 50 | 2019 |
