A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus J Barke, RF Seipke, S Grüschow, D Heavens, N Drou, MJ Bibb, RJM Goss, ... BMC biology 8, 1-10, 2010 | 278 | 2010 |
Isolation and structure elucidation of Chlorofusin, a novel p53-MDM2 antagonist from a Fusarium sp. SJ Duncan, S Grüschow, DH Williams, C McNicholas, R Purewal, ... Journal of the American Chemical Society 123 (4), 554-560, 2001 | 248 | 2001 |
An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity JS Athukoralage, SA McMahon, C Zhang, S Grüschow, S Graham, ... Nature 577 (7791), 572-575, 2020 | 141 | 2020 |
Control of cyclic oligoadenylate synthesis in a type III CRISPR system C Rouillon, JS Athukoralage, S Graham, S Grüschow, MF White Elife 7, e36734, 2018 | 140 | 2018 |
Ring nucleases deactivate type III CRISPR ribonucleases by degrading cyclic oligoadenylate JS Athukoralage, C Rouillon, S Graham, S Grüschow, MF White Nature 562 (7726), 277-280, 2018 | 106 | 2018 |
Scope and potential of halogenases in biosynthetic applications DRM Smith, S Grüschow, RJM Goss Current opinion in chemical biology 17 (2), 276-283, 2013 | 103 | 2013 |
New pacidamycin antibiotics through precursor‐directed biosynthesis S Grüschow, EJ Rackham, B Elkins, PLA Newill, LM Hill, RJM Goss ChemBioChem 10 (2), 355-360, 2009 | 94 | 2009 |
Pacidamycin biosynthesis: identification and heterologous expression of the first uridyl peptide antibiotic gene cluster EJ Rackham, S Grüschow, AE Ragab, S Dickens, RJM Goss ChemBioChem 11 (12), 1700-1709, 2010 | 86 | 2010 |
Enzymatic assembly of the bis-indole core of rebeccamycin T Nishizawa, S Grüschow, DHE Jayamaha, C Nishizawa-Harada, ... Journal of the American Chemical Society 128 (3), 724-725, 2006 | 81 | 2006 |
A type III CRISPR ancillary ribonuclease degrades its cyclic oligoadenylate activator JS Athukoralage, S Graham, S Grüschow, C Rouillon, MF White Journal of Molecular Biology 431 (15), 2894-2899, 2019 | 67 | 2019 |
Cyclic nucleotide-induced helical structure activates a TIR immune effector G Hogrel, A Guild, S Graham, H Rickman, S Grüschow, Q Bertrand, ... Nature 608 (7924), 808-812, 2022 | 60 | 2022 |
Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence S Grüschow, JS Athukoralage, S Graham, T Hoogeboom, MF White Nucleic acids research 47 (17), 9259-9270, 2019 | 56 | 2019 |
The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling JS Athukoralage, S Graham, C Rouillon, S Grüschow, CM Czekster, ... Elife 9, e55852, 2020 | 49 | 2020 |
Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor type III polyketide synthases S Grüschow, TJ Buchholz, W Seufert, JS Dordick, DH Sherman WILEY-VCH Verlag, 2007 | 48 | 2007 |
The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence W Zhu, S McQuarrie, S Grüschow, SA McMahon, S Graham, TM Gloster, ... Nucleic acids research 49 (5), 2777-2789, 2021 | 44 | 2021 |
Specificity and sensitivity of an RNA targeting type III CRISPR complex coupled with a NucC endonuclease effector S Grüschow, CS Adamson, MF White Nucleic acids research 49 (22), 13122-13134, 2021 | 43 | 2021 |
Regulation of the RNA and DNA nuclease activities required for Pyrococcus furiosus Type III-B CRISPR–Cas immunity K Foster, S Grüschow, S Bailey, MF White, MP Terns Nucleic acids research 48 (8), 4418-4434, 2020 | 35 | 2020 |
Structural characterization of the mitomycin 7‐O‐methyltransferase S Singh, A Chang, RD Goff, CA Bingman, S Grüschow, DH Sherman, ... Proteins: Structure, Function, and Bioinformatics 79 (7), 2181-2188, 2011 | 33 | 2011 |
Detection of VM55599 and Preparaherquamide from Aspergillus japonicus and Penicillium fellutanum: Biosynthetic Implications Y Ding, S Gruschow, TJ Greshock, JM Finefield, DH Sherman, ... Journal of natural products 71 (9), 1574-1578, 2008 | 33 | 2008 |
Hydroxyquinone O-methylation in mitomycin biosynthesis S Grüschow, LC Chang, Y Mao, DH Sherman Journal of the American Chemical Society 129 (20), 6470-6476, 2007 | 32 | 2007 |