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Sabine Gruschow
Sabine Gruschow
University of St Andrews, School of Chemistry
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A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus
J Barke, RF Seipke, S Grüschow, D Heavens, N Drou, MJ Bibb, RJM Goss, ...
BMC biology 8, 1-10, 2010
2782010
Isolation and structure elucidation of Chlorofusin, a novel p53-MDM2 antagonist from a Fusarium sp.
SJ Duncan, S Grüschow, DH Williams, C McNicholas, R Purewal, ...
Journal of the American Chemical Society 123 (4), 554-560, 2001
2482001
An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity
JS Athukoralage, SA McMahon, C Zhang, S Grüschow, S Graham, ...
Nature 577 (7791), 572-575, 2020
1412020
Control of cyclic oligoadenylate synthesis in a type III CRISPR system
C Rouillon, JS Athukoralage, S Graham, S Grüschow, MF White
Elife 7, e36734, 2018
1402018
Ring nucleases deactivate type III CRISPR ribonucleases by degrading cyclic oligoadenylate
JS Athukoralage, C Rouillon, S Graham, S Grüschow, MF White
Nature 562 (7726), 277-280, 2018
1062018
Scope and potential of halogenases in biosynthetic applications
DRM Smith, S Grüschow, RJM Goss
Current opinion in chemical biology 17 (2), 276-283, 2013
1032013
New pacidamycin antibiotics through precursor‐directed biosynthesis
S Grüschow, EJ Rackham, B Elkins, PLA Newill, LM Hill, RJM Goss
ChemBioChem 10 (2), 355-360, 2009
942009
Pacidamycin biosynthesis: identification and heterologous expression of the first uridyl peptide antibiotic gene cluster
EJ Rackham, S Grüschow, AE Ragab, S Dickens, RJM Goss
ChemBioChem 11 (12), 1700-1709, 2010
862010
Enzymatic assembly of the bis-indole core of rebeccamycin
T Nishizawa, S Grüschow, DHE Jayamaha, C Nishizawa-Harada, ...
Journal of the American Chemical Society 128 (3), 724-725, 2006
812006
A type III CRISPR ancillary ribonuclease degrades its cyclic oligoadenylate activator
JS Athukoralage, S Graham, S Grüschow, C Rouillon, MF White
Journal of Molecular Biology 431 (15), 2894-2899, 2019
672019
Cyclic nucleotide-induced helical structure activates a TIR immune effector
G Hogrel, A Guild, S Graham, H Rickman, S Grüschow, Q Bertrand, ...
Nature 608 (7924), 808-812, 2022
602022
Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence
S Grüschow, JS Athukoralage, S Graham, T Hoogeboom, MF White
Nucleic acids research 47 (17), 9259-9270, 2019
562019
The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling
JS Athukoralage, S Graham, C Rouillon, S Grüschow, CM Czekster, ...
Elife 9, e55852, 2020
492020
Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor type III polyketide synthases
S Grüschow, TJ Buchholz, W Seufert, JS Dordick, DH Sherman
WILEY-VCH Verlag, 2007
482007
The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence
W Zhu, S McQuarrie, S Grüschow, SA McMahon, S Graham, TM Gloster, ...
Nucleic acids research 49 (5), 2777-2789, 2021
442021
Specificity and sensitivity of an RNA targeting type III CRISPR complex coupled with a NucC endonuclease effector
S Grüschow, CS Adamson, MF White
Nucleic acids research 49 (22), 13122-13134, 2021
432021
Regulation of the RNA and DNA nuclease activities required for Pyrococcus furiosus Type III-B CRISPR–Cas immunity
K Foster, S Grüschow, S Bailey, MF White, MP Terns
Nucleic acids research 48 (8), 4418-4434, 2020
352020
Structural characterization of the mitomycin 7‐O‐methyltransferase
S Singh, A Chang, RD Goff, CA Bingman, S Grüschow, DH Sherman, ...
Proteins: Structure, Function, and Bioinformatics 79 (7), 2181-2188, 2011
332011
Detection of VM55599 and Preparaherquamide from Aspergillus japonicus and Penicillium fellutanum: Biosynthetic Implications
Y Ding, S Gruschow, TJ Greshock, JM Finefield, DH Sherman, ...
Journal of natural products 71 (9), 1574-1578, 2008
332008
Hydroxyquinone O-methylation in mitomycin biosynthesis
S Grüschow, LC Chang, Y Mao, DH Sherman
Journal of the American Chemical Society 129 (20), 6470-6476, 2007
322007
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Artikelen 1–20