methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles A Akalin, M Kormaksson, S Li, FE Garrett-Bakelman, ME Figueroa, ... Genome biology 13, 1-9, 2012 | 1864 | 2012 |
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells LP Vu, BF Pickering, Y Cheng, S Zaccara, D Nguyen, G Minuesa, T Chou, ... Nature medicine 23 (11), 1369-1376, 2017 | 1089 | 2017 |
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight FE Garrett-Bakelman, M Darshi, SJ Green, RC Gur, L Lin, BR Macias, ... Science 364 (6436), eaau8650, 2019 | 949 | 2019 |
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia S Li, FE Garrett-Bakelman, SS Chung, MA Sanders, T Hricik, F Rapaport, ... Nature medicine 22 (7), 792-799, 2016 | 399 | 2016 |
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia A Akalin, FE Garrett-Bakelman, M Kormaksson, J Busuttil, L Zhang, ... PLoS genetics 8 (6), e1002781, 2012 | 338 | 2012 |
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling OA Guryanova, K Shank, B Spitzer, L Luciani, RP Koche, ... Nature medicine 22 (12), 1488-1495, 2016 | 256 | 2016 |
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ... Cell reports 4 (3), 578-588, 2013 | 194 | 2013 |
Chemotherapy induces senescence-like resilient cells capable of initiating AML recurrence C Duy, M Li, M Teater, C Meydan, FE Garrett-Bakelman, TC Lee, CR Chin, ... Cancer discovery 11 (6), 1542-1561, 2021 | 176 | 2021 |
Chromatin Architecture near a Potential 3′ End of the Igh Locus Involves Modular Regulation of Histone Modifications during B-Cell Development and In Vivo … FE Garrett, AV Emelyanov, MA Sepulveda, P Flanagan, S Volpi, F Li, ... Molecular and cellular biology 25 (4), 1511-1525, 2005 | 149 | 2005 |
CD99 is a therapeutic target on disease stem cells in myeloid malignancies SS Chung, WS Eng, W Hu, M Khalaj, FE Garrett-Bakelman, M Tavakkoli, ... Science translational medicine 9 (374), eaaj2025, 2017 | 144 | 2017 |
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia AH Shih, C Meydan, K Shank, FE Garrett-Bakelman, PS Ward, ... Cancer discovery 7 (5), 494-505, 2017 | 125 | 2017 |
Enhanced reduced representation bisulfite sequencing for assessment of DNA methylation at base pair resolution FE Garrett-Bakelman, CK Sheridan, TJ Kacmarczyk, J Ishii, D Betel, ... JoVE (Journal of Visualized Experiments), e52246, 2015 | 123 | 2015 |
An optimized algorithm for detecting and annotating regional differential methylation S Li, FE Garrett-Bakelman, A Akalin, P Zumbo, R Levine, BL To, ID Lewis, ... BMC bioinformatics 14, 1-9, 2013 | 122 | 2013 |
Epigenetic identity in AML depends on disruption of nonpromoter regulatory elements and is affected by antagonistic effects of mutations in epigenetic modifiers JL Glass, D Hassane, BJ Wouters, H Kunimoto, R Avellino, ... Cancer discovery 7 (8), 868-883, 2017 | 119 | 2017 |
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment B Will, TO Vogler, B Bartholdy, F Garrett-Bakelman, J Mayer, L Barreyro, ... Nature immunology 14 (5), 437-445, 2013 | 116 | 2013 |
Cooperative epigenetic remodeling by TET2 loss and NRAS mutation drives myeloid transformation and MEK inhibitor sensitivity H Kunimoto, C Meydan, A Nazir, J Whitfield, K Shank, F Rapaport, ... Cancer cell 33 (1), 44-59. e8, 2018 | 94 | 2018 |
Dynamic evolution of clonal epialleles revealed by methclone S Li, F Garrett-Bakelman, AE Perl, SM Luger, C Zhang, BL To, ID Lewis, ... Genome biology 15, 1-12, 2014 | 85 | 2014 |
Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells OA Guryanova, YK Lieu, FE Garrett-Bakelman, B Spitzer, JL Glass, ... Leukemia 30 (5), 1133-1142, 2016 | 77 | 2016 |
Temporal telomere and DNA damage responses in the space radiation environment JJ Luxton, MJ McKenna, LE Taylor, KA George, SR Zwart, BE Crucian, ... Cell Reports 33 (10), 2020 | 68 | 2020 |
The effects of Eculizumab on the pathology of malignant atrophic papulosis CM Magro, X Wang, F Garrett-Bakelman, J Laurence, LS Shapiro, ... Orphanet Journal of Rare Diseases 8, 1-9, 2013 | 65 | 2013 |