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Miratul Muqit
Miratul Muqit
Professor of Experimental Neurology, MRC Protein Phosphorylation & Ubiquitylation Unit
Geverifieerd e-mailadres voor doctors.org.uk - Homepage
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Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1
EM Valente, PM Abou-Sleiman, V Caputo, MMK Muqit, K Harvey, ...
Science 304 (5674), 1158-1160, 2004
41022004
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
DG Healy, M Falchi, SS O'Sullivan, V Bonifati, A Durr, S Bressman, ...
The Lancet Neurology 7 (7), 583-590, 2008
16462008
Expanding insights of mitochondrial dysfunction in Parkinson's disease
PM Abou-Sleiman, MMK Muqit, NW Wood
Nature Reviews Neuroscience 7 (3), 207-219, 2006
11112006
Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia
SE Browne, AC Bowling, U Macgarvey, MJ Baik, SC Berger, MMK Muquit, ...
Annals of Neurology: Official Journal of the American Neurological …, 1997
10701997
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ...
Open biology 2 (5), 120080, 2012
9172012
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
A Kazlauskaite, C Kondapalli, R Gourlay, DG Campbell, MS Ritorto, ...
Biochemical Journal 460 (1), 127-141, 2014
8002014
Inhibition of neuronal nitric oxide synthase by 7‐nitroindazole protects against MPTP‐induced neurotoxicity in mice
JB Schulz, RT Matthews, MMK Muqit, SE Browne, MF Beal
Journal of neurochemistry 64 (2), 936-939, 1995
5371995
Basal mitophagy occurs independently of PINK1 in mouse tissues of high metabolic demand
TG McWilliams, AR Prescott, L Montava-Garriga, G Ball, F Singh, E Barini, ...
Cell metabolism 27 (2), 439-449. e5, 2018
5062018
mito-QC illuminates mitophagy and mitochondrial architecture in vivo
TG McWilliams, AR Prescott, GFG Allen, J Tamjar, MJ Munson, ...
Journal of Cell Biology 214 (3), 333-345, 2016
4272016
PINK1 protein in normal human brain and Parkinson's disease
S Gandhi, MMK Muqit, L Stanyer, DG Healy, PM Abou-Sleiman, ...
Brain 129 (7), 1720-1731, 2006
4162006
PINK1 and Parkin: emerging themes in mitochondrial homeostasis
TG McWilliams, MMK Muqit
Current opinion in cell biology 45, 83-91, 2017
3012017
Modelling neurodegenerative diseases in Drosophila: a fruitful approach?
MMK Muqit, MB Feany
Nature Reviews Neuroscience 3 (3), 237-243, 2002
2472002
Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog
DT Rogerson, A Sachdeva, K Wang, T Haq, A Kazlauskaite, SM Hancock, ...
Nature chemical biology 11 (7), 496-503, 2015
2352015
Binding to serine 65‐phosphorylated ubiquitin primes Parkin for optimal PINK 1‐dependent phosphorylation and activation
A Kazlauskaite, RJ Martínez‐Torres, S Wilkie, A Kumar, J Peltier, ...
EMBO reports 16 (8), 939-954, 2015
2262015
A heterozygous effect for PINK1 mutations in Parkinson's disease?
PM Abou‐Sleiman, MMK Muqit, NQ McDonald, YX Yang, S Gandhi, ...
Annals of neurology 60 (4), 414-419, 2006
2072006
Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress
MMK Muqit, PM Abou‐Sleiman, AT Saurin, K Harvey, S Gandhi, E Deas, ...
Journal of neurochemistry 98 (1), 156-169, 2006
1912006
Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1
YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ...
The EMBO journal 34 (22), 2840-2861, 2015
1852015
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
A Kazlauskaite, V Kelly, C Johnson, C Baillie, CJ Hastie, M Peggie, ...
Open biology 4 (3), 130213, 2014
1462014
UCHL‐1 is not a Parkinson's disease susceptibility gene
DG Healy, PM Abou‐Sleiman, JP Casas, KR Ahmadi, T Lynch, S Gandhi, ...
Annals of Neurology: Official Journal of the American Neurological …, 2006
1442006
PINK1 (PARK6) associated Parkinson disease in Ireland
DG Healy, PM Abou-Sleiman, JM Gibson, OA Ross, S Jain, S Gandhi, ...
Neurology 63 (8), 1486-1488, 2004
1352004
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Artikelen 1–20