Doriana Fruci
Doriana Fruci
Department of Paediatric Haematology/Oncology, Ospedale Pediatrico Bambino Ges¨, Rome, Italy
Verified email at
Cited by
Cited by
Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum
L Saveanu, O Carroll, V Lindo, M Del Val, D Lopez, Y Lepelletier, F Greer, ...
Nature immunology 6 (7), 689-697, 2005
Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM
L Fontana, ME Fiori, S Albini, L Cifaldi, S Giovinazzi, M Forloni, R Boldrini, ...
PloS one 3 (5), e2236, 2008
Influence of the tumor microenvironment on NK cell function in solid tumors
O Melaiu, V Lucarini, L Cifaldi, D Fruci
Frontiers in Immunology 10, 3038, 2020
Control of cross‐presentation during dendritic cell maturation
BC Gil‐Torregrosa, AM Lennon‐DumÚnil, B Kessler, P Guermonprez, ...
European journal of immunology 34 (2), 398-407, 2004
Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non‐lymphoid human tissues
D Fruci, P Giacomini, MR Nicotra, M Forloni, R Fraioli, L Saveanu, ...
Journal of cellular physiology 216 (3), 742-749, 2008
Tumor-infiltrating T lymphocytes improve clinical outcome of therapy-resistant neuroblastoma
M Mina, R Boldrini, A Citti, P Romania, V D'Alicandro, M De Ioris, ...
Oncoimmunology 4 (9), e1019981, 2015
Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines
D Fruci, S Ferracuti, MZ Limongi, V Cunsolo, E Giorda, R Fraioli, L Sibilio, ...
The Journal of Immunology 176 (8), 4869-4879, 2006
Two brc-abl junction peptides bind HLA-A3 molecules and allow specific induction of human cytotoxic T lymphocytes.
G Greco, D Fruci, D Accapezzato, V Barnaba, R Nisini, G Alimena, ...
Leukemia 10 (4), 693-699, 1996
Efficient MHC class I-independent amino-terminal trimming of epitope precursor peptides in the endoplasmic reticulum
D Fruci, G Niedermann, RH Butler, PM Van Endert
Immunity 15 (3), 467-476, 2001
Multidrug resistance and cancer stem cells in neuroblastoma and hepatoblastoma
A Alisi, WC Cho, F Locatelli, D Fruci
International journal of molecular sciences 14 (12), 24706-24725, 2013
Beyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases
L Saveanu, D Fruci, PM Van Endert
Molecular immunology 39 (3-4), 203-215, 2002
PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma
O Melaiu, M Mina, M Chierici, R Boldrini, G Jurman, P Romania, ...
Clinical Cancer Research 23 (15), 4462-4472, 2017
NF-κB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells
M Forloni, S Albini, MZ Limongi, L Cifaldi, R Boldrini, MR Nicotra, ...
Cancer research 70 (3), 916-924, 2010
Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer
L Cifaldi, P Romania, S Lorenzi, F Locatelli, D Fruci
International journal of molecular sciences 13 (7), 8338-8352, 2012
The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: insights from genomic-wide association studies
A Fierabracci, A Milillo, F Locatelli, D Fruci
Autoimmunity reviews 12 (2), 281-288, 2012
IRF1 and NF-kB restore MHC class I-restricted tumor antigen processing and presentation to cytotoxic T cells in aggressive neuroblastoma
S Lorenzi, M Forloni, L Cifaldi, C Antonucci, A Citti, R Boldrini, M Pezzullo, ...
Public Library of Science 7 (10), e46928, 2012
Natural killer cells efficiently reject lymphoma silenced for the endoplasmic reticulum aminopeptidase associated with antigen processing
L Cifaldi, E Lo Monaco, M Forloni, E Giorda, S Lorenzi, S Petrini, ...
Cancer research 71 (5), 1597-1606, 2011
A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition
E Stratikos, A Stamogiannos, E Zervoudi, D Fruci
Frontiers in oncology 4, 363, 2014
Quantifying recruitment of cytosolic peptides for HLA class I presentation: impact of TAP transport
D Fruci, G Lauvau, L Saveanu, M Amicosante, RH Butler, A Polack, ...
The Journal of Immunology 170 (6), 2977-2984, 2003
Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma
FLDF Ombretta Melaiu, Marco Chierici, Valeria Lucarini, Giuseppe Jurman ...
Nature Communications, 2020
The system can't perform the operation now. Try again later.
Articles 1–20