Sebastiaan Meijsing
Sebastiaan Meijsing
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DNA binding site sequence directs glucocorticoid receptor structure and activity
SH Meijsing, MA Pufall, AY So, DL Bates, L Chen, KR Yamamoto
Science 324 (5925), 407-410, 2009
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome
RC DeKelver, VM Choi, EA Moehle, DE Paschon, D Hockemeyer, ...
Genome research 20 (8), 1133-1142, 2010
An affective disorder in zebrafish with mutation of the glucocorticoid receptor
L Ziv, A Muto, PJ Schoonheim, SH Meijsing, D Strasser, HA Ingraham, ...
Molecular psychiatry 18 (6), 681-691, 2013
The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae
SH Meijsing, AE Ehrenhofer-Murray
Genes & development 15 (23), 3169-3182, 2001
ChIP-exo signal associated with DNA-binding motifs provides insight into the genomic binding of the glucocorticoid receptor and cooperating transcription factors
SR Starick, J Ibn-Salem, M Jurk, C Hernandez, MI Love, HR Chung, ...
Genome research 25 (6), 825-835, 2015
Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity
JC Wang, N Shah, C Pantoja, SH Meijsing, JD Ho, TS Scanlan, ...
Genes & development 20 (6), 689-699, 2006
Interleukin-15 decreases proteolysis in skeletal muscle: a direct effect
S Busquets, MT Figueras, S Meijsing, N Carbó, LBS Quinn, V Almendro, ...
International journal of molecular medicine 16 (3), 471-476, 2005
Cancer cachexia: a therapeutic approach
JM Argilés, SH Meijsing, J Pallarés‐Trujillo, X Guirao, FJ López‐Soriano
Medicinal Research Reviews 21 (1), 83-101, 2001
The ligand binding domain controls glucocorticoid receptor dynamics independent of ligand release
SH Meijsing, C Elbi, HF Luecke, GL Hager, KR Yamamoto
Molecular and cellular biology 27 (7), 2442-2451, 2007
Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity
S Schöne, M Jurk, MB Helabad, I Dror, I Lebars, B Kieffer, P Imhof, ...
Nature communications 7 (1), 12621, 2016
A naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms
M Thomas-Chollier, LC Watson, SB Cooper, MA Pufall, JS Liu, K Borzym, ...
Proceedings of the National Academy of Sciences 110 (44), 17826-17831, 2013
Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2
V Malik, LV Glaser, D Zimmer, S Velychko, M Weng, M Holzner, M Arend, ...
Nature communications 10 (1), 3477, 2019
Mechanisms of glucocorticoid-regulated gene transcription
SH Meijsing
Glucocorticoid Signaling: From Molecules to Mice to Man, 59-81, 2015
The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function
VL Batalha, DG Ferreira, JE Coelho, JS Valadas, R Gomes, ...
Scientific Reports 6 (1), 31493, 2016
Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation
MI Love, MR Huska, M Jurk, R Schöpflin, SR Starick, K Schwahn, ...
Nucleic acids research 45 (4), 1805-1819, 2017
Airway epithelial cells are crucial targets of glucocorticoids in a mouse model of allergic asthma
C Klaßen, A Karabinskaya, L Dejager, S Vettorazzi, J Van Moorleghem, ...
The Journal of Immunology 199 (1), 48-61, 2017
Genomic dissection of enhancers uncovers principles of combinatorial regulation and cell type-specific wiring of enhancer–promoter contacts
V Thormann, MC Rothkegel, R Schöpflin, LV Glaser, P Djuric, N Li, ...
Nucleic acids research 46 (6), 2868-2882, 2018
Synthetic STARR-seq reveals how DNA shape and sequence modulate transcriptional output and noise
S Schöne, M Bothe, E Einfeldt, M Borschiwer, P Benner, M Vingron, ...
PLoS genetics 14 (11), e1007793, 2018
Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites
M Kulik, M Bothe, G Kibar, A Fuchs, S Schöne, S Prekovic, ...
Nucleic acids research 49 (7), 3856-3875, 2021
CRUP: a comprehensive framework to predict condition-specific regulatory units
A Ramisch, V Heinrich, LV Glaser, A Fuchs, X Yang, P Benner, ...
Genome biology 20, 1-23, 2019
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