H. Christian Eberl
H. Christian Eberl
Cellzome GmbH, a GSK company
Geverifieerd e-mailadres voor gsk.com
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Dynamic readers for 5-(hydroxy) methylcytosine and its oxidized derivatives
CG Spruijt, F Gnerlich, AH Smits, T Pfaffeneder, PWTC Jansen, C Bauer, ...
Cell 152 (5), 1146-1159, 2013
7602013
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers
M Vermeulen, HC Eberl, F Matarese, H Marks, S Denissov, F Butter, ...
Cell 142 (6), 967-980, 2010
5862010
Hsp90 is regulated by a switch point in the C‐terminal domain
M Retzlaff, M Stahl, HC Eberl, S Lagleder, J Beck, H Kessler, J Buchner
EMBO reports 10 (10), 1147-1153, 2009
1422009
A map of general and specialized chromatin readers in mouse tissues generated by label-free interaction proteomics
HC Eberl, CG Spruijt, CD Kelstrup, M Vermeulen, M Mann
Molecular cell 49 (2), 368-378, 2013
1332013
Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics
P Mertins, HC Eberl, J Renkawitz, JV Olsen, ML Tremblay, M Mann, ...
Molecular & Cellular Proteomics 7 (9), 1763-1777, 2008
1152008
Sequestration by IFIT1 impairs translation of 2′ O-unmethylated capped RNA
M Habjan, P Hubel, L Lacerda, C Benda, C Holze, CH Eberl, A Mann, ...
PLoS pathogens 9 (10), 2013
1112013
Quantitative proteomics for epigenetics
HC Eberl, M Mann, M Vermeulen
Chembiochem 12 (2), 224-234, 2011
692011
H2A. Z. 2.2 is an alternatively spliced histone H2A. Z variant that causes severe nucleosome destabilization
C Bönisch, K Schneider, S Pünzeler, SM Wiedemann, C Bielmeier, ...
Nucleic acids research 40 (13), 5951-5964, 2012
672012
Design of amidobenzimidazole STING receptor agonists with systemic activity
JM Ramanjulu, GS Pesiridis, J Yang, N Concha, R Singhaus, SY Zhang, ...
Nature 564 (7736), 439-443, 2018
662018
Dicer-dependent and-independent Argonaute2 protein interaction networks in mammalian cells
A Frohn, HC Eberl, J Stöhr, E Glasmacher, S Rüdel, V Heissmeyer, ...
Molecular & Cellular Proteomics 11 (11), 1442-1456, 2012
482012
A double-barrel liquid chromatography-tandem mass spectrometry (LC-MS/MS) system to quantify 96 interactomes per day
F Hosp, RA Scheltema, HC Eberl, NA Kulak, EC Keilhauer, K Mayr, ...
Molecular & Cellular Proteomics 14 (7), 2030-2041, 2015
232015
Monitoring cell-surface N-glycoproteome dynamics by quantitative proteomics reveals mechanistic insights into macrophage differentiation
M Kalxdorf, S Gade, HC Eberl, M Bantscheff
Molecular & Cellular Proteomics 16 (5), 770-785, 2017
172017
Fragment-based covalent ligand screening enables rapid discovery of inhibitors for the RBR E3 ubiquitin ligase HOIP
H Johansson, YC Isabella Tsai, K Fantom, CW Chung, S Kümper, ...
Journal of the American Chemical Society 141 (6), 2703-2712, 2019
132019
H3. Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3. 3-H4 binding and deposition requirements
LM Zink, E Delbarre, HC Eberl, EC Keilhauer, C Bönisch, S Pünzeler, ...
Nucleic acids research 45 (10), 5691-5706, 2017
72017
519 Gil-Cruz C, Ziebuhr J, Thiel V, Pichlmair A. 2013. Sequestration by IFIT1 impairs 520 translation of 2'O-unmethylated capped RNA
M Habjan, P Hubel, L Lacerda, C Benda, C Holze, CH Eberl, A Mann, ...
PLoS Pathog 9, e1003663, 0
6
Identifying drug targets in tissues and whole blood with thermal-shift profiling
J Perrin, T Werner, N Kurzawa, A Rutkowska, DD Childs, M Kalxdorf, ...
Nature Biotechnology 38 (3), 303-308, 2020
22020
Mechanistic Basis of Cabotegravir–Glucuronide Disposition in Humans
M Patel, HC Eberl, A Wolf, E Pierre, JW Polli, MJ Zamek-Gliszczynski
Journal of Pharmacology and Experimental Therapeutics 370 (2), 269-277, 2019
22019
A hit deconstruction approach for the discovery of fetal hemoglobin inducers
AB Benowitz, HC Eberl, CL Erickson-Miller, AG Gilmartin, ER Gore, ...
Bioorganic & medicinal chemistry letters 28 (23-24), 3676-3680, 2018
22018
Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo
J Perrin, T Werner, N Kurzawa, DD Childs, M Kalxdorf, A Rutkowska, ...
bioRxiv, 500306, 2018
22018
A Photoaffinity Displacement Assay and Probes to Study the Cyclin‐Dependent Kinase Family
EK Grant, DJ Fallon, HC Eberl, KGM Fantom, F Zappacosta, C Messenger, ...
Angewandte Chemie International Edition 58 (48), 17322-17327, 2019
12019
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Artikelen 1–20