Christian M.T. Spahn
Christian M.T. Spahn
Professor der Biophysik, Charite - Universitätsmedizin Berlin
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Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit
CMT Spahn, JS Kieft, RA Grassucci, PA Penczek, K Zhou, JA Doudna, ...
Science 291 (5510), 1959-1962, 2001
Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions
CMT Spahn, R Beckmann, N Eswar, PA Penczek, A Sali, G Blobel, ...
Cell 107 (3), 373-386, 2001
Solution structure of the E. coli 70S ribosome at 11.5 Å resolution
IS Gabashvili, RK Agrawal, CMT Spahn, RA Grassucci, DI Svergun, ...
Cell 100 (5), 537-549, 2000
Architecture of the protein-conducting channel associated with the translating 80S ribosome
R Beckmann, CMT Spahn, N Eswar, J Helmers, PA Penczek, A Sali, ...
Cell 107 (3), 361-372, 2001
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
M Halic, T Becker, MR Pool, CMT Spahn, RA Grassucci, J Frank, ...
Nature 427 (6977), 808-814, 2004
Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation
CMT Spahn, MG Gomez‐Lorenzo, RA Grassucci, R Jørgensen, ...
The EMBO journal 23 (5), 1008-1019, 2004
A new system for naming ribosomal proteins
N Ban, R Beckmann, JHD Cate, JD Dinman, F Dragon, SR Ellis, ...
Current opinion in structural biology 24, 165-169, 2014
The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre
J Fritsch, P Scheerer, S Frielingsdorf, S Kroschinsky, B Friedrich, O Lenz, ...
Nature 479 (7372), 249-252, 2011
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
AH Ratje, J Loerke, A Mikolajka, M Brünner, PW Hildebrand, AL Starosta, ...
Nature 468 (7324), 713-716, 2010
Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor
CMT Spahn, E Jan, A Mulder, RA Grassucci, P Sarnow, J Frank
Cell 118 (4), 465-475, 2004
Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin
JM Harms, DN Wilson, F Schluenzen, SR Connell, T Stachelhaus, ...
Molecular cell 30 (1), 26-38, 2008
Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM
J Sengupta, J Nilsson, R Gursky, CMT Spahn, P Nissen, J Frank
Nature structural & molecular biology 11 (10), 957-962, 2004
Throwing a spanner in the works: antibiotics and the translation apparatus
CMT Spahn, CD Prescott
Journal of molecular medicine 74 (8), 423-439, 1996
[19] Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy
G Blaha, U Stelzl, CMT Spahn, RK Agrawal, J Frank, KH Nierhaus
Academic Press 317, 292-309, 2000
Structure of the ribosome-bound cricket paralysis virus IRES RNA
M Schüler, SR Connell, A Lescoute, J Giesebrecht, M Dabrowski, ...
Nature structural & molecular biology 13 (12), 1092-1096, 2006
GTPase activation of elongation factor EF‐Tu by the ribosome during decoding
JC Schuette, FV Murphy IV, AC Kelley, JR Weir, J Giesebrecht, ...
The EMBO journal 28 (6), 755-765, 2009
Visualization of Trna Movements on the Escherichia coli 70s Ribosome during the Elongation Cycle
RK Agrawal, CMT Spahn, P Penczek, RA Grassucci, KH Nierhaus, ...
The Journal of cell biology 150 (3), 447-460, 2000
Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors
SR Connell, C Takemoto, DN Wilson, H Wang, K Murayama, T Terada, ...
Molecular cell 25 (5), 751-764, 2007
Three‐dimensional cryo‐electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 Å resolution
MG Gomez‐Lorenzo, CMT Spahn, RK Agrawal, RA Grassucci, P Penczek, ...
The EMBO journal 19 (11), 2710-2718, 2000
Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: functional implications
RK Agrawal, MR Sharma, MC Kiel, G Hirokawa, TM Booth, CMT Spahn, ...
Proceedings of the National Academy of Sciences 101 (24), 8900-8905, 2004
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