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Yitian Zhou
Yitian Zhou
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Worldwide distribution of cytochrome P450 alleles: a meta‐analysis of population‐scale sequencing projects
Y Zhou, M Ingelman‐Sundberg, VM Lauschke
Clinical Pharmacology & Therapeutics 102 (4), 688-700, 2017
6012017
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study
JJ Swen, CH van der Wouden, LEN Manson, H Abdullah-Koolmees, ...
The Lancet 401 (10374), 347-356, 2023
2972023
Integrating rare genetic variants into pharmacogenetic drug response predictions
M Ingelman-Sundberg, S Mkrtchian, Y Zhou, VM Lauschke
Human genomics 12, 1-12, 2018
2202018
Prediction of drug-induced hepatotoxicity using long-term stable primary hepatic 3D spheroid cultures in chemically defined conditions
SU Vorrink, Y Zhou, M Ingelman-Sundberg, VM Lauschke
Toxicological Sciences 163 (2), 655-665, 2018
1852018
An optimized prediction framework to assess the functional impact of pharmacogenetic variants
Y Zhou, S Mkrtchian, M Kumondai, M Hiratsuka, VM Lauschke
The pharmacogenomics journal 19 (2), 115-126, 2019
1292019
Comprehensive evaluation of organotypic and microphysiological liver models for prediction of drug-induced liver injury
Y Zhou, JX Shen, VM Lauschke
Frontiers in pharmacology 10, 1093, 2019
1132019
Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity
VM Lauschke, Y Zhou, M Ingelman-Sundberg
Pharmacology & therapeutics 197, 122-152, 2019
1052019
Computational methods for the pharmacogenetic interpretation of next generation sequencing data
Y Zhou, K Fujikura, S Mkrtchian, VM Lauschke
Frontiers in Pharmacology 9, 1437, 2018
642018
The genetic landscape of major drug metabolizing cytochrome P450 genes—an updated analysis of population-scale sequencing data
Y Zhou, VM Lauschke
The Pharmacogenomics Journal 22 (5), 284-293, 2022
602022
Ethnogeographic and inter-individual variability of human ABC transporters
Q Xiao, Y Zhou, VM Lauschke
Human Genetics 139 (5), 623-646, 2020
452020
Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost‐Effectiveness of Preemptive Pharmacogenetic Testing
Y Zhou, K Krebs, L Milani, VM Lauschke
Clinical Pharmacology & Therapeutics 109 (1), 160-174, 2021
442021
Population pharmacogenomics: an update on ethnogeographic differences and opportunities for precision public health
Y Zhou, VM Lauschke
Human Genetics 141 (6), 1113-1136, 2022
382022
Pharmacogenomics in the era of next generation sequencing–from byte to bedside
LE Russell, Y Zhou, AA Almousa, JK Sodhi, CK Nwabufo, VM Lauschke
Drug Metabolism Reviews 53 (2), 253-278, 2021
372021
Organotypic and microphysiological human tissue models for drug discovery and development—current state-of-the-art and future perspectives
S Youhanna, AM Kemas, L Preiss, Y Zhou, JX Shen, SD Cakal, ...
Pharmacological Reviews 74 (1), 141-206, 2022
362022
Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier
Y Zhou, C Dagli Hernandez, VM Lauschke
British Journal of Cancer 123 (12), 1782-1789, 2020
352020
Global distribution of functionally important CYP2C9 alleles and their inferred metabolic consequences
Y Zhou, L Nevosadová, E Eliasson, VM Lauschke
Human genomics 17 (1), 15, 2023
312023
Computational tools to assess the functional consequences of rare and noncoding pharmacogenetic variability
Y Zhou, VM Lauschke
Clinical Pharmacology & Therapeutics 110 (3), 626-636, 2021
302021
Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk [S]
Y Zhou, R Mägi, L Milani, VM Lauschke
Journal of lipid research 59 (10), 1987-2000, 2018
302018
Rare genetic variant burden in DPYD predicts severe fluoropyrimidine-related toxicity risk
E De Mattia, M Silvestri, J Polesel, F Ecca, S Mezzalira, L Scarabel, ...
Biomedicine & Pharmacotherapy 154, 113644, 2022
292022
Challenges and opportunities associated with rare-variant pharmacogenomics
Y Zhou, R Tremmel, E Schaeffeler, M Schwab, VM Lauschke
Trends in pharmacological sciences 43 (10), 852-865, 2022
292022
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