| TCP1 complex is a molecular chaperone in tubulin biogenesis MB Yaffe, GW Farr, D Miklos, AL Horwich, ML Sternlicht, H Sternlicht Nature 358 (6383), 245-248, 1992 | 572 | 1992 |
| Two families of chaperonin: physiology and mechanism AL Horwich, WA Fenton, E Chapman, GW Farr Annu. Rev. Cell Dev. Biol. 23, 115-145, 2007 | 537 | 2007 |
| The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo H Sternlicht, GW Farr, ML Sternlicht, JK Driscoll, K Willison, MB Yaffe Proceedings of the National Academy of Sciences 90 (20), 9422-9426, 1993 | 395 | 1993 |
| ATP-bound states of GroEL captured by cryo-electron microscopy NA Ranson, GW Farr, AM Roseman, B Gowen, WA Fenton, AL Horwich, ... Cell 107 (7), 869-879, 2001 | 342 | 2001 |
| GroEL− GroES-mediated protein folding AL Horwich, GW Farr, WA Fenton Chemical reviews 106 (5), 1917-1930, 2006 | 297 | 2006 |
| Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation J Hinnerwisch, WA Fenton, KJ Furtak, GW Farr, AL Horwich Cell 121 (7), 1029-1041, 2005 | 274 | 2005 |
| Multivalent binding of nonnative substrate proteins by the chaperonin GroEL GW Farr, K Furtak, MB Rowland, NA Ranson, HR Saibil, T Kirchhausen, ... Cell 100 (5), 561-573, 2000 | 238 | 2000 |
| An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans J Wang, GW Farr, DH Hall, F Li, K Furtak, L Dreier, AL Horwich PLoS genetics 5 (1), e1000350, 2009 | 227 | 2009 |
| GroEL/GroES-mediated folding of a protein too large to be encapsulated TK Chaudhuri, GW Farr, WA Fenton, S Rospert, AL Horwich Cell 107 (2), 235-246, 2001 | 225 | 2001 |
| Chaperonin-mediated folding in the eukaryotic cytosol proceeds through rounds of release of native and nonnative forms GW Farr, EC Scharl, RJ Schumacher, S Sondek, AL Horwich Cell 89 (6), 927-937, 1997 | 219 | 1997 |
| ATP-triggered conformational changes delineate substrate-binding and-folding mechanics of the GroEL chaperonin DK Clare, D Vasishtan, S Stagg, J Quispe, GW Farr, M Topf, AL Horwich, ... Cell 149 (1), 113-123, 2012 | 210 | 2012 |
| Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT KA Won, RJ Schumacher, GW Farr, AL Horwich, SI Reed Molecular and cellular biology 18 (12), 7584-7589, 1998 | 196 | 1998 |
| Allosteric signaling of ATP hydrolysis in GroEL–GroES complexes NA Ranson, DK Clare, GW Farr, D Houldershaw, AL Horwich, HR Saibil Nature structural & molecular biology 13 (2), 147-152, 2006 | 180 | 2006 |
| Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS J Wang, GW Farr, CJ Zeiss, DJ Rodriguez-Gil, JH Wilson, K Furtak, ... Proceedings of the National Academy of Sciences 106 (5), 1392-1397, 2009 | 168 | 2009 |
| Role of the γ‐phosphate of ATP in triggering protein folding by GroEL–GroES: function, structure and energetics C Chaudhry, GW Farr, MJ Todd, HS Rye, AT Brunger, PD Adams, ... The EMBO Journal 22 (19), 4877-4887, 2003 | 154 | 2003 |
| Global aggregation of newly translated proteins in an Escherichia coli strain deficient of the chaperonin GroEL E Chapman, GW Farr, R Usaite, K Furtak, WA Fenton, TK Chaudhuri, ... Proceedings of the National Academy of Sciences 103 (43), 15800-15805, 2006 | 151 | 2006 |
| Topologies of a substrate protein bound to the chaperonin GroEL N Elad, GW Farr, DK Clare, EV Orlova, AL Horwich, HR Saibil Molecular cell 26 (3), 415-426, 2007 | 113 | 2007 |
| Release of both native and non-native proteins from a cis-only GroEL ternary complex SG Burston, JS Weissman, GW Farr, WA Fenton, AL Norwich Nature 383 (6595), 96-99, 1996 | 105 | 1996 |
| Folding with and without encapsulation by cis‐and trans‐only GroEL–GroES complexes GW Farr, WA Fenton, TK Chaudhuri, DK Clare, HR Saibil, AL Horwich The EMBO journal 22 (13), 3220-3230, 2003 | 92 | 2003 |
| Substrate polypeptide presents a load on the apical domains of the chaperonin GroEL F Motojima, C Chaudhry, WA Fenton, GW Farr, AL Horwich Proceedings of the National Academy of Sciences 101 (42), 15005-15012, 2004 | 88 | 2004 |
