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Jonathan D Ashwell
Jonathan D Ashwell
Principal Investigator, National Institutes of Health
Verified email at pop.nci.nih.gov
Title
Cited by
Cited by
Year
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
Y Yang, S Fang, JP Jensen, AM Weissman, JD Ashwell
Science 288 (5467), 874-877, 2000
13062000
Glucocorticoids in T cell development and function
JD Ashwell, FWM Lu, MS Vacchio
Annual review of immunology 18 (1), 309-345, 2000
10642000
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation
CJ Wu, DB Conze, T Li, SM Srinivasula, JD Ashwell
Nature cell biology 8 (4), 398-406, 2006
6522006
IAPs: what's in a name?
SM Srinivasula, JD Ashwell
Molecular cell 30 (2), 123-135, 2008
6272008
Genomic instability in Gadd45a-deficient mice
MC Hollander, MS Sheikh, DV Bulavin, K Lundgren, L Augeri-Henmueller, ...
Nature genetics 23 (2), 176-184, 1999
6141999
Outer membrane vesicles of a human commensal mediate immune regulation and disease protection
Y Shen, MLG Torchia, GW Lawson, CL Karp, JD Ashwell, SK Mazmanian
Cell host & microbe 12 (4), 509-520, 2012
6042012
TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
X Li, Y Yang, JD Ashwell
Nature 416 (6878), 345-347, 2002
5732002
The many paths to p38 mitogen-activated protein kinase activation in the immune system
JD Ashwell
Nature Reviews Immunology 6 (7), 532-540, 2006
4812006
Failure to synthesize the T cell CD3-ζ chain: structure and function of a partial T cell receptor complex
JJ Sussman, JS Bonifacino, J Lippincott-Schwartz, AM Weissman, T Saito, ...
Cell 52 (1), 85-95, 1988
4591988
Steroid production in the thymus: implications for thymocyte selection.
MS Vacchio, V Papadopoulos, JD Ashwell
The Journal of experimental medicine 179 (6), 1835-1846, 1994
4451994
Programmed T lymphocyte death. Cell activation-and steroid-induced pathways are mutually antagonistic.
CM Zacharchuk, M Merćep, PK Chakraborti, SS Simons Jr, JD Ashwell
Journal of immunology (Baltimore, Md.: 1950) 145 (12), 4037-4045, 1990
4201990
Genetic and mutational analysis of the T-cell antigen receptor
JD Ashwell, RD Klausner
Annual review of immunology 8 (1), 139-167, 1990
4201990
Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells.
MK Jenkins, JD Ashwell, RH Schwartz
Journal of immunology (Baltimore, Md.: 1950) 140 (10), 3324-3330, 1988
3961988
Alternative p38 activation pathway mediated by T cell receptor–proximal tyrosine kinases
JM Salvador, PR Mittelstadt, T Guszczynski, TD Copeland, H Yamaguchi, ...
Nature immunology 6 (4), 390-395, 2005
3952005
Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ
PR Mittelstadt, JD Ashwell
Journal of Biological Chemistry 276 (31), 29603-29610, 2001
3632001
Cell growth cycle block of T cell hybridomas upon activation with antigen.
JD Ashwell, RE Cunningham, PD Noguchi, D Hernandez
The Journal of experimental medicine 165 (1), 173-194, 1987
3101987
Optineurin negatively regulates TNFα-induced NF-κB activation by competing with NEMO for ubiquitinated RIP
G Zhu, CJ Wu, Y Zhao, JD Ashwell
Current Biology 17 (16), 1438-1443, 2007
3092007
Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis
JM Lenczowski, L Domínguez, AM Eder, LB King, CM Zacharchuk, ...
Molecular and cellular biology, 1997
3061997
Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor-and toll-like receptor-mediated NF-κB activation
DB Conze, CJ Wu, JA Thomas, A Landstrom, JD Ashwell
Molecular and cellular biology 28 (10), 3538-3547, 2008
2942008
Structural basis for recognition of diubiquitins by NEMO
YC Lo, SC Lin, CC Rospigliosi, DB Conze, CJ Wu, JD Ashwell, D Eliezer, ...
Molecular cell 33 (5), 602-615, 2009
2922009
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