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Jacqueline A Brinkman
Jacqueline A Brinkman
Verified email at email.unc.edu
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Cited by
Year
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
D Yu, NE Richardson, CL Green, AB Spicer, ME Murphy, V Flores, C Jang, ...
Cell metabolism 33 (5), 905-922. e6, 2021
2082021
A novel rapamycin analog is highly selective for mTORC1 in vivo
KH Schreiber, SIA Apelo, D Yu, JA Brinkman, MC Velarde, FA Syed, ...
Nature communications 10 (1), 1-12, 2019
1462019
Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages
SFH Waqas, AC Hoang, YT Lin, G Ampem, H Azegrouz, L Balogh, ...
The Journal of clinical investigation 127 (7), 2842-2854, 2017
912017
Short‐term methionine deprivation improves metabolic health via sexually dimorphic, mTORCI‐independent mechanisms
D Yu, SE Yang, BR Miller, JA Wisinski, DS Sherman, JA Brinkman, ...
The FASEB Journal 32 (6), 3471-3482, 2018
782018
Calorie-restriction-induced insulin sensitivity is mediated by adipose mTORC2 and not required for lifespan extension
D Yu, JL Tomasiewicz, SE Yang, BR Miller, MH Wakai, DS Sherman, ...
Cell reports 29 (1), 236-248. e3, 2019
752019
Hypothalamic mTORC2 is essential for metabolic health and longevity
K Chellappa, JA Brinkman, S Mukherjee, M Morrison, MI Alotaibi, ...
Aging cell 18 (5), e13014, 2019
562019
Chronic intermittent hypoxia worsens bleomycin-induced lung fibrosis in rats
RK Braun, O Broytman, FM Braun, JA Brinkman, A Clithero, D Modi, ...
Respiratory physiology & neurobiology 256, 97-108, 2018
382018
Integrating mouse and human genetic data to move beyond GWAS and identify causal genes in cholesterol metabolism
Z Li, JA Votava, GJM Zajac, JN Nguyen, FBL Jaimes, SM Ly, JA Brinkman, ...
Cell metabolism, 2020
322020
Small-molecule drug repurposing to target DNA damage repair and response pathways
JA Brinkman, Y Liu, SJ Kron
Seminars in cancer biology 68, 230-241, 2021
272021
Ovariectomy uncouples lifespan from metabolic health and reveals a sex-hormone-dependent role of hepatic mTORC2 in aging
SIA Apelo, A Lin, JA Brinkman, E Meyer, M Morrison, JL Tomasiewicz, ...
Elife 9, e56177, 2020
272020
The metabolic response to a low amino acid diet is independent of diet-induced shifts in the composition of the gut microbiome
HH Pak, NE Cummings, CL Green, JA Brinkman, D Yu, JL Tomasiewicz, ...
Scientific reports 9 (1), 1-12, 2019
212019
Age-dependent protection of insulin secretion in diet induced obese mice
ER De Leon, JA Brinkman, RJ Fenske, T Gregg, BA Schmidt, ...
Scientific reports 8 (1), 1-11, 2018
202018
Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer
N Ricco, A Flor, D Wolfgeher, EV Efimova, A Ramamurthy, OK Appelbe, ...
Molecular oncology 13 (9), 1927-1943, 2019
192019
Chronic intermittent hypoxia increases airway hyperresponsiveness during house dust mites exposures in rats
M Teodorescu, R Song, JA Brinkman, RL Sorkness
Respiratory Research 24 (1), 189, 2023
22023
Ovalbumin–Induced Airway Inflammation Enhances Hypoxic Ventilatory Response In Rats
O Broytman, J Brinkman, D Pegelow, B Morgan, M Teodorescu
The FASEB Journal 31 (1_supplement), 728.9-728.9, 2017
22017
Airway Hyperresponsiveness To Methacholine In House Dust Mite-Allergic Rats Exposed To Chronic Intermittent Hypoxia
O Broytman, J Brinkman, D Pegelow, M Teodorescu
C110. OSA OVERLAPS: ASTHMA, COPD, OBESITY HYPOVENTILATION SYNDROME, AND LUNG …, 2017
12017
Abstract SY21-03: Shutting off cancer's fountain of youth: Targeting metabolism to block repair and reverse immortality
E Efimova, Y Liu, J Lutze, T Collins, A Flor, J Brinkman, D Wolfgeher, ...
Cancer Research 79 (13_Supplement), SY21-03-SY21-03, 2019
2019
DIETARY ISOLEUCINE IS A KEY REGULATOR OF METABOLIC HEALTH: A04
D Yu, N Cummings, C Green, A Spicer, V Flores, C Jang, I Kasza, ...
Journal of Investigative Medicine 67 (5), 2019
2019
UNCOVERING THE ROLE OF FASTING AND REDUCED CALORIC INTAKE IN THE METABOLIC BENEFITS OF CALORIE RESTRICTION: A26
H Pak, C Green, N Cummings, J Brinkman, S Yang, D Yu, J Tomasiewicz, ...
Journal of Investigative Medicine 67 (5), 894-895, 2019
2019
Abstract B021: Imaging immunotherapy in the tumor microenvironment in 3D
SJ Kron, SSY Lee, D Scholten, VSY Bindokas, J Brinkman
Cancer Immunology Research 7 (2_Supplement), B021-B021, 2019
2019
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Articles 1–20