| Proteasomes and their kin: proteases in the machine age CM Pickart, RE Cohen Nature reviews Molecular cell biology 5 (3), 177-187, 2004 | 937 | 2004 |
| A cryptic protease couples deubiquitination and degradation by the proteasome T Yao, RE Cohen Nature 419 (6905), 403-407, 2002 | 919 | 2002 |
| Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde M Hu, P Li, M Li, W Li, T Yao, JW Wu, W Gu, RE Cohen, Y Shi Cell 111 (7), 1041-1054, 2002 | 719 | 2002 |
| Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome YA Lam, W Xu, GN DeMartino, RE Cohen Nature 385 (6618), 737-740, 1997 | 584 | 1997 |
| Structure and mechanisms of the proteasome‐associated deubiquitinating enzyme USP14 M Hu, P Li, L Song, PD Jeffrey, TA Chernova, KD Wilkinson, RE Cohen, ... The EMBO journal 24 (21), 3747-3756, 2005 | 485 | 2005 |
| Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1 T Yao, L Song, W Xu, GN DeMartino, L Florens, SK Swanson, ... Nature cell biology 8 (9), 994-1002, 2006 | 388 | 2006 |
| Structural basis for the specificity of ubiquitin C-terminal hydrolases SC Johnston, SM Riddle, RE Cohen, CP Hill The EMBO journal 18 (14), 3877-3887, 1999 | 378 | 1999 |
| Donanemab in early symptomatic Alzheimer disease: the TRAILBLAZER-ALZ 2 randomized clinical trial JR Sims, JA Zimmer, CD Evans, M Lu, P Ardayfio, JD Sparks, AM Wessels, ... Jama 330 (6), 512-527, 2023 | 365 | 2023 |
| The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains BJ Winborn, SM Travis, SV Todi, KM Scaglione, P Xu, AJ Williams, ... Journal of Biological Chemistry 283 (39), 26436-26443, 2008 | 317 | 2008 |
| Inhibition of the 26 S proteasome by polyubiquitin chains synthesized to have defined lengths J Piotrowski, R Beal, L Hoffman, KD Wilkinson, RE Cohen, CM Pickart Journal of Biological Chemistry 272 (38), 23712-23721, 1997 | 267 | 1997 |
| K63‐specific deubiquitination by two JAMM/MPN+ complexes: BRISC‐associated Brcc36 and proteasomal Poh1 EM Cooper, C Cutcliffe, TZ Kristiansen, A Pandey, CM Pickart, RE Cohen The EMBO journal 28 (6), 621-631, 2009 | 266 | 2009 |
| The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-β signalling SJ Wicks, K Haros, M Maillard, L Song, RE Cohen, P Dijke, A Chantry Oncogene 24 (54), 8080-8084, 2005 | 253 | 2005 |
| Linkage-specific avidity defines the lysine 63-linked polyubiquitin-binding preference of rap80 JJ Sims, RE Cohen Molecular cell 33 (6), 775-783, 2009 | 250 | 2009 |
| Poly-ubiquitin binding by the polyglutamine disease protein ataxin-3 links its normal function to protein surveillance pathways Y Chai, SS Berke, RE Cohen, HL Paulson Journal of Biological Chemistry 279 (5), 3605-3611, 2004 | 218 | 2004 |
| Structural insights into the assembly and function of the SAGA deubiquitinating module NL Samara, AB Datta, CE Berndsen, X Zhang, T Yao, RE Cohen, ... Science 328 (5981), 1025-1029, 2010 | 215 | 2010 |
| Linkage and sequence analysis of mannose-rich glycoprotein core oligosaccharides by proton nuclear magnetic resonance spectroscopy RE Cohen, CE Ballou Biochemistry 19 (18), 4345-4358, 1980 | 189 | 1980 |
| Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex T Yao, L Song, J Jin, Y Cai, H Takahashi, SK Swanson, MP Washburn, ... Molecular cell 31 (6), 909-917, 2008 | 178 | 2008 |
| Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1 T Wang, L Yin, EM Cooper, MY Lai, S Dickey, CM Pickart, D Fushman, ... Journal of molecular biology 386 (4), 1011-1023, 2009 | 165 | 2009 |
| Saccharomyces cerevisiae [yeast] mutants that make mannoproteins with a truncated carbohydrate outer chain. L Ballou, RE Cohen, CE Ballou Journal of biological chemistry 255, 1980 | 163 | 1980 |
| Specificity of the ubiquitin isopeptidase in the PA700 regulatory complex of 26 S proteasomes YA Lam, GN DeMartino, CM Pickart, RE Cohen Journal of Biological Chemistry 272 (45), 28438-28446, 1997 | 159 | 1997 |
