| A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals LM Walker, MD Simek, F Priddy, JS Gach, D Wagner, MB Zwick, ... PLoS pathogens 6 (8), e1001028, 2010 | 439 | 2010 |
| Engineering of Pichia pastoris for improved production of antibody fragments B Gasser, M Maurer, J Gach, R Kunert, D Mattanovich Biotechnology and bioengineering 94 (2), 353-361, 2006 | 238 | 2006 |
| Fc-glycosylation influences Fcγ receptor binding and cell-mediated anti-HIV activity of monoclonal antibody 2G12 DN Forthal, JS Gach, G Landucci, J Jez, R Strasser, R Kunert, ... The Journal of Immunology 185 (11), 6876-6882, 2010 | 164 | 2010 |
| Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface L Song, ZYJ Sun, KE Coleman, MB Zwick, JS Gach, J Wang, EL Reinherz, ... Proceedings of the National Academy of Sciences 106 (22), 9057-9062, 2009 | 144 | 2009 |
| A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies R Pejchal, JS Gach, FM Brunel, RM Cardoso, RL Stanfield, PE Dawson, ... Journal of virology 83 (17), 8451-8462, 2009 | 118 | 2009 |
| Recent insights into the HIV/AIDS pandemic JC Becerra, LS Bildstein, JS Gach Microbial cell 3 (9), 451, 2016 | 101 | 2016 |
| The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells S Gupta, JS Gach, JC Becerra, TB Phan, J Pudney, Z Moldoveanu, ... PLoS pathogens 9 (11), e1003776, 2013 | 98 | 2013 |
| HIV-specific CD4-induced antibodies mediate broad and potent antibody-dependent cellular cytotoxicity activity and are commonly detected in plasma from HIV-infected humans KL Williams, V Cortez, AS Dingens, JS Gach, S Rainwater, JF Weis, ... EBioMedicine 2 (10), 1464-1477, 2015 | 64 | 2015 |
| HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition M Vaccari, S Fourati, SN Gordon, DR Brown, M Bissa, L Schifanella, ... Nature medicine 24 (6), 847-856, 2018 | 63 | 2018 |
| Glycan modulation and sulfoengineering of anti–HIV-1 monoclonal antibody PG9 in plants A Loos, JS Gach, T Hackl, D Maresch, T Henkel, A Porodko, D Bui-Minh, ... Proceedings of the National Academy of Sciences 112 (41), 12675-12680, 2015 | 49 | 2015 |
| High level expression of a promising anti-idiotypic antibody fragment vaccine against HIV-1 in Pichia pastoris JS Gach, M Maurer, R Hahn, B Gasser, D Mattanovich, H Katinger, ... Journal of biotechnology 128 (4), 735-746, 2007 | 46 | 2007 |
| Targeting HIV-1 gp41 in close proximity to the membrane using antibody and other molecules J S Gach, D P Leaman, M B Zwick Current topics in medicinal chemistry 11 (24), 2997-3021, 2011 | 40 | 2011 |
| Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques A Verma, BA Schmidt, SR Elizaldi, NK Nguyen, KA Walter, Z Beck, ... Journal of virology 94 (6), 10.1128/jvi. 01737-19, 2020 | 31 | 2020 |
| HIV-1 specific antibody titers and neutralization among chronically infected patients on long-term suppressive antiretroviral therapy (ART): a cross-sectional study JS Gach, CJ Achenbach, V Chromikova, B Berzins, N Lambert, ... PLOS one 9 (1), e85371, 2014 | 27 | 2014 |
| Structure-based design of a protein immunogen that displays an HIV-1 gp41 neutralizing epitope RL Stanfield, JP Julien, R Pejchal, JS Gach, MB Zwick, IA Wilson Journal of molecular biology 414 (3), 460-476, 2011 | 27 | 2011 |
| Human immunodeficiency virus type-1 (HIV-1) evades antibody-dependent phagocytosis JS Gach, M Bouzin, MP Wong, V Chromikova, A Gorlani, KT Yu, ... PLoS pathogens 13 (12), e1006793, 2017 | 26 | 2017 |
| Synthesis and analysis of the membrane proximal external region epitopes of HIV‐1 S Ingale, JS Gach, MB Zwick, PE Dawson Journal of Peptide Science 16 (12), 716-722, 2010 | 25 | 2010 |
| 4E10-resistant HIV-1 isolated from four subjects with rare membrane-proximal external region polymorphisms KJ Nakamura, JS Gach, L Jones, K Semrau, J Walter, F Bibollet-Ruche, ... PLOS one 5 (3), e9786, 2010 | 25 | 2010 |
| Combination adenovirus and protein vaccines prevent infection or reduce viral burden after heterologous clade C simian-human immunodeficiency virus mucosal challenge DC Malherbe, J Mendy, L Vang, PT Barnette, J Reed, SK Lakhashe, ... Journal of virology 92 (2), 10.1128/jvi. 01092-17, 2018 | 24 | 2018 |
| A human antibody to the CD4 binding site of gp120 capable of highly potent but sporadic cross clade neutralization of primary HIV-1 JS Gach, H Quendler, T Tong, KM Narayan, SX Du, RG Whalen, ... PLOS one 8 (8), e72054, 2013 | 24 | 2013 |
Donald ForthalProfessor of Medicine, University of California, IrvineGeverifieerd e-mailadres voor uci.edu
