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DU Chao
DU Chao
Geverifieerd e-mailadres voor biology.leidenuniv.nl
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Antibiotic production in Streptomyces is organized by a division of labor through terminal genomic differentiation
Z Zhang, C Du, F de Barsy, M Liem, A Liakopoulos, GP van Wezel, ...
Science advances 6 (3), eaay5781, 2020
582020
Metabolomics-Driven Discovery of a Prenylated Isatin Antibiotic Produced by Streptomyces Species MBT28
C Wu, C Du, J Gubbens, YH Choi, GP Van Wezel
Journal of natural products 78 (10), 2355-2363, 2015
562015
Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides
AM Kloosterman, P Cimermancic, SS Elsayed, C Du, M Hadjithomas, ...
PLoS biology 18 (12), e3001026, 2020
512020
iTRAQ-based proteomic analysis of the metabolism mechanism associated with silicon response in the marine diatom Thalassiosira pseudonana
C Du, JR Liang, DD Chen, B Xu, WH Zhuo, YH Gao, CP Chen, C Bowler, ...
Journal of proteome research 13 (2), 720-734, 2014
432014
Discovery of C-Glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a Combined NMR-Based Metabolomics and Bioinformatics Workflow
C Wu, C Du, K Ichinose, YH Choi, GP Van Wezel
Journal of natural products 80 (2), 269-277, 2017
332017
Mining for microbial gems: integrating proteomics in the postgenomic natural product discovery pipeline
C Du, GP van Wezel
Proteomics 18 (18), 1700332, 2018
312018
MALDI-TOF MS analysis of the extracellular polysaccharides released by the diatom Thalassiosira pseudonana under various nutrient conditions
XX Ai, JR Liang, YH Gao, SCL Lo, FWF Lee, CP Chen, CS Luo, C Du
Journal of Applied Phycology 27, 673-684, 2015
232015
Enzyme-constrained models and omics analysis of Streptomyces coelicolor reveal metabolic changes that enhance heterologous production
S Sulheim, T Kumelj, D van Dissel, A Salehzadeh-Yazdi, C Du, ...
Iscience 23 (9), 101525, 2020
222020
The ubiquitous catechol moiety elicits siderophore and angucycline production in Streptomyces
DA van Bergeijk, SS Elsayed, C Du, IN Santiago, AM Roseboom, L Zhang, ...
Communications Chemistry 5 (1), 14, 2022
52022
Functional and structural insights into a novel promiscuous ketoreductase of the lugdunomycin biosynthetic pathway
X Xiao, SS Elsayed, C Wu, HU van der Heul, M Metsä-Ketelä, C Du, ...
ACS chemical biology 15 (9), 2529-2538, 2020
42020
Discovery of actinomycin L, a new member of the actinomycin family of antibiotics
NV Machushynets, SS Elsayed, C Du, MA Siegler, M de la Cruz, ...
Scientific Reports 12 (1), 1-13, 2022
32022
Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products
AM Kloosterman, P Cimermancic, SS Elsayed, C Du, M Hadjithomas, ...
bioRxiv, 2020.05. 19.104752, 2020
22020
New from old: discovery of the novel antibiotic actinomycin L in Streptomyces sp. MBT27
N Machushynets, SS Elsayed, C Du, MA Siegler, M de la Cruz, ...
bioRxiv, 2021.10. 12.464064, 2021
12021
Antibiotic production in Streptomyces is organized by a division of labour through terminal genomic differentiation
Z Zhang, C Du, F de Barsy, M Liem, A Liakopoulos, GP van Wezel, ...
bioRxiv, 560136, 2019
12019
Genomescale model constrained by proteomics reveals metabolic rearrangements in the heterologous host streptomyces coelicolor
S Sulheim, T Kumelj, D Van Dissel, A Salehzadeh-Yazdi, C Du, K Nieselt, ...
bioRxiv, 2019
12019
The cryptic qin gene cluster of Streptomyces sp. MBT76 specifies C-glycosylpyranonaphthoquinones with new chemistry
C Wu, C Du, K Ichinose, YH Choi, GP van Wezel
Discovery of Novel Antibiotics from Actinomycetes by Integrated Metabolomics …, 1985
11985
System-Wide Analysis of the GATC-Binding Nucleoid-Associated Protein Gbn and Its Impact on Streptomyces Development
C Du, J Willemse, AM Erkelens, VJ Carrion, RT Dame, GP van Wezel
Msystems 7 (3), e00061-22, 2022
2022
Adrenaline-mediated activation of antibiotic production in Streptomyces highlights catechol as elicitor of specialized metabolism
G van Wezel, D van Bergeijk, S Elsayed, C Du, IN Santiago, A Roseboom, ...
2021
Adrenaline-mediated activation of antibiotic production in Streptomyces highlights catechol as elicitor of specialized metabolism
W Gv, B Dv, S Elsayed, C Du, IN Santiago, A Roseboom, L Zhang, ...
2021
Discovery of C-glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by
C Wu, C Du, K Ichinose, YH Choi, GP van Wezel
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Artikelen 1–20