| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13120* | 2021 |
| Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the … C Théry, KW Witwer, E Aikawa, MJ Alcaraz, JD Anderson, ... Journal of extracellular vesicles 7 (1), 1535750, 2018 | 8216 | 2018 |
| The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5 KMA Rouschop, T van den Beucken, L Dubois, H Niessen, J Bussink, ... The Journal of clinical investigation 120 (1), 127-141, 2010 | 885 | 2010 |
| Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney JC Leemans, G Stokman, N Claessen, KM Rouschop, GJD Teske, ... The Journal of clinical investigation 115 (10), 2894-2903, 2005 | 670 | 2005 |
| LC3/GABARAP family proteins: autophagy‐(un) related functions MBE Schaaf, TG Keulers, MA Vooijs, KMA Rouschop The FASEB journal 30 (12), 3961-3978, 2016 | 551 | 2016 |
| PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS KM Rouschop, LJ Dubois, TG Keulers, T van den Beucken, P Lambin, ... Proceedings of the National Academy of Sciences 110 (12), 4622-4627, 2013 | 229 | 2013 |
| Hypoxia induced impairment of NK cell cytotoxicity against multiple myeloma can be overcome by IL-2 activation of the NK cells S Sarkar, WTV Germeraad, KMA Rouschop, EMP Steeghs, M Gelder, ... PloS one 8 (5), e64835, 2013 | 164 | 2013 |
| Protection against renal ischemia reperfusion injury by CD44 disruption KMA Rouschop, JJTH Roelofs, N Claessen, P da Costa Martins, ... Journal of the American Society of Nephrology 16 (7), 2034-2043, 2005 | 160 | 2005 |
| Autophagy is required during cycling hypoxia to lower production of reactive oxygen species KMA Rouschop, CHMA Ramaekers, MBE Schaaf, TGH Keulers, ... Radiotherapy and Oncology 92 (3), 411-416, 2009 | 156 | 2009 |
| Regulation of autophagy through multiple independent hypoxic signaling pathways K Rouschop, BG Wouters Current molecular medicine 9 (4), 417-424, 2009 | 138 | 2009 |
| Level of activation of the unfolded protein response correlates with Paneth cell apoptosis in human small intestine exposed to ischemia/reperfusion J Grootjans, CM Hodin, JJ de Haan, JPM Derikx, KMA Rouschop, ... Gastroenterology 140 (2), 529-539. e3, 2011 | 137 | 2011 |
| Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3 H Mujcic, A Nagelkerke, KMA Rouschop, S Chung, N Chaudary, PN Span, ... Clinical Cancer Research 19 (22), 6126-6137, 2013 | 136 | 2013 |
| CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy KMA Rouschop, ME Sewnath, N Claessen, JJTH Roelofs, I Hoedemaeker, ... Journal of the American Society of Nephrology 15 (3), 674-686, 2004 | 130 | 2004 |
| Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3 H Mujcic, T Rzymski, KMA Rouschop, M Koritzinsky, M Milani, AL Harris, ... Radiotherapy and Oncology 92 (3), 450-459, 2009 | 129 | 2009 |
| Tissue-type plasminogen activator modulates inflammatory responses and renal function in ischemia reperfusion injury JJTH Roelofs, KMA Rouschop, JC Leemans, N Claessen, AM de Boer, ... Journal of the American society of nephrology 17 (1), 131-140, 2006 | 128 | 2006 |
| EGFR signaling and autophagy dependence for growth, survival, and therapy resistance B Jutten, K Rouschop Cell cycle 13 (1), 42-51, 2014 | 126 | 2014 |
| Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium EO Pettersen, P Ebbesen, RG Gieling, KJ Williams, L Dubois, P Lambin, ... Journal of enzyme inhibition and medicinal chemistry 30 (5), 689-721, 2015 | 125 | 2015 |
| Small-molecule activation of p53 blocks hypoxia-inducible factor 1α and vascular endothelial growth factor expression in vivo and leads to tumor cell apoptosis in normoxia and … J Yang, A Ahmed, E Poon, N Perusinghe, A de Haven Brandon, G Box, ... Molecular and cellular biology 29 (8), 2243-2253, 2009 | 108 | 2009 |
| Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response M Wennemers, J Bussink, B Scheijen, ID Nagtegaal, ... Breast Cancer Research 13, 1-15, 2011 | 96 | 2011 |
| Phosphorylation of eIF2α is required for mRNA translation inhibition and survival during moderate hypoxia M Koritzinsky, KMA Rouschop, T van den Beucken, MG Magagnin, ... Radiotherapy and oncology 83 (3), 353-361, 2007 | 82 | 2007 |
