Peter van der Kraan
Peter van der Kraan
Professor of Experimental Rheumatology, Radboud University, Medical Centre
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Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?
PM Van der Kraan, WB Van den Berg
Osteoarthritis and cartilage 20 (3), 223-232, 2012
Osteophytes: relevance and biology
PM van der Kraan, WB van den Berg
Osteoarthritis and cartilage 15 (3), 237-244, 2007
Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint.
HM Van Beuningen, PM Van der Kraan, OJ Arntz, WB Van den Berg
Laboratory investigation; a journal of technical methods and pathology 71 (2 …, 1994
TGF-β and osteoarthritis
ENB Davidson, PM Van der Kraan, WB Van Den Berg
Osteoarthritis and cartilage 15 (6), 597-604, 2007
Interaction of chondrocytes, extracellular matrix and growth factors: relevance for articular cartilage tissue engineering
PM Van der Kraan, P Buma, T Van Kuppevelt, WB Van Den Berg
Osteoarthritis and cartilage 10 (8), 631-637, 2002
Differential effects of local application of BMP-2 or TGF-β1 on both articular cartilage composition and osteophyte formation
HM van Beuningen, HL Glansbeek, PM van der Kraan, WB van den Berg
Osteoarthritis and Cartilage 6 (5), 306-317, 1998
Crucial role of macrophages in matrix metalloproteinase–mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3
AB Blom, PL van Lent, S Libregts, AE Holthuysen, PM van der Kraan, ...
Arthritis & Rheumatism 56 (1), 147-157, 2007
Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-β injections
HM Van Beuningen, HL Glansbeek, PM Van Der Kraan, ...
Osteoarthritis and Cartilage 8 (1), 25-33, 2000
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation
AC Bakker, FAJ Van De Loo, HM Van Beuningen, P Sime, P Van Lent, ...
Osteoarthritis and cartilage 9 (2), 128-136, 2001
Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis
AB Blom, PLEM van Lent, AEM Holthuysen, PM van der Kraan, J Roth, ...
Osteoarthritis and cartilage 12 (8), 627-635, 2004
Inhibition of endogenous TGF-β during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair
A Scharstuhl, HL Glansbeek, HM van Beuningen, EL Vitters, ...
The Journal of Immunology 169 (1), 507-514, 2002
Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice
ENB Davidson, DFG Remst, EL Vitters, HM van Beuningen, AB Blom, ...
The Journal of Immunology 182 (12), 7937-7945, 2009
TGF-beta signaling in chondrocyte terminal differentiation and osteoarthritis: modulation and integration of signaling pathways through receptor-Smads
PM Van der Kraan, ENB Davidson, A Blom, WB Van den Berg
Osteoarthritis and cartilage 17 (12), 1539-1545, 2009
Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis
E Thijssen, A Van Caam, PM Van Der Kraan
Rheumatology 54 (4), 588-600, 2015
Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity
ENB Davidson, A Scharstuhl, EL Vitters, PM Van Der Kraan, ...
Arthritis research & therapy 7 (6), 1-10, 2005
Linkage of chondroitin-sulfate to type I collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro
JLC van Susante, J Pieper, P Buma, TH van Kuppevelt, H van Beuningen, ...
Biomaterials 22 (17), 2359-2369, 2001
The role of metabolism in the pathogenesis of osteoarthritis
A Mobasheri, MP Rayman, O Gualillo, J Sellam, P Van Der Kraan, ...
Nature Reviews Rheumatology 13 (5), 302-311, 2017
Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt‐induced signaling protein 1
AB Blom, SM Brockbank, PL van Lent, HM van Beuningen, J Geurts, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2009
Chondrocyte behavior in fibrin glue in vitro
GN Homminga, P Buma, HWJ Koot, PM van der Kraan, WB van den Berg
Acta orthopaedica Scandinavica 64 (4), 441-445, 1993
Culture of chondrocytes in alginate and collagen carrier gels
JLC van Susante, P Buma, GJVM van Osch, D Versleyen, ...
Acta Orthopaedica Scandinavica 66 (6), 549-556, 1995
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