| Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration? PM Van der Kraan, WB Van den Berg Osteoarthritis and cartilage 20 (3), 223-232, 2012 | 727 | 2012 |
| Osteophytes: relevance and biology PM Van Der Kraan, WB Van Den Berg Osteoarthritis and cartilage 15 (3), 237-244, 2007 | 646 | 2007 |
| The role of metabolism in the pathogenesis of osteoarthritis A Mobasheri, MP Rayman, O Gualillo, J Sellam, P Van Der Kraan, ... Nature Reviews Rheumatology 13 (5), 302-311, 2017 | 560 | 2017 |
| TGF-β and osteoarthritis ENB Davidson, PM Van der Kraan, WB Van Den Berg Osteoarthritis and cartilage 15 (6), 597-604, 2007 | 526 | 2007 |
| Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint. HM Van Beuningen, PM Van der Kraan, OJ Arntz, WB Van den Berg Laboratory investigation; a journal of technical methods and pathology 71 (2 …, 1994 | 493 | 1994 |
| Crucial role of macrophages in matrix metalloproteinase–mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3 AB Blom, PL Van Lent, S Libregts, AE Holthuysen, PM Van Der Kraan, ... Arthritis & Rheumatism 56 (1), 147-157, 2007 | 408 | 2007 |
| Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis AB Blom, PLEM van Lent, AEM Holthuysen, PM van der Kraan, J Roth, ... Osteoarthritis and cartilage 12 (8), 627-635, 2004 | 403 | 2004 |
| Interaction of chondrocytes, extracellular matrix and growth factors: relevance for articular cartilage tissue engineering PM Van der Kraan, P Buma, T Van Kuppevelt, WB Van Den Berg Osteoarthritis and cartilage 10 (8), 631-637, 2002 | 389 | 2002 |
| Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis E Thijssen, A Van Caam, PM Van Der Kraan Rheumatology 54 (4), 588-600, 2015 | 381 | 2015 |
| Differential effects of local application of BMP-2 or TGF-β1 on both articular cartilage composition and osteophyte formation HM van Beuningen, HL Glansbeek, PM van der Kraan, WB van den Berg Osteoarthritis and Cartilage 6 (5), 306-317, 1998 | 379 | 1998 |
| Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation AC Bakker, FAJ Van De Loo, HM Van Beuningen, P Sime, P Van Lent, ... Osteoarthritis and cartilage 9 (2), 128-136, 2001 | 362 | 2001 |
| TGF-beta signaling in chondrocyte terminal differentiation and osteoarthritis: modulation and integration of signaling pathways through receptor-Smads PM Van der Kraan, ENB Davidson, A Blom, WB Van den Berg Osteoarthritis and cartilage 17 (12), 1539-1545, 2009 | 349 | 2009 |
| Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-β injections HM Van Beuningen, HL Glansbeek, PM Van Der Kraan, ... Osteoarthritis and Cartilage 8 (1), 25-33, 2000 | 342 | 2000 |
| Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice EN Blaney Davidson, DFG Remst, EL Vitters, HM van Beuningen, ... The Journal of Immunology 182 (12), 7937-7945, 2009 | 337 | 2009 |
| Inhibition of endogenous TGF-β during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair A Scharstuhl, HL Glansbeek, HM van Beuningen, EL Vitters, ... The Journal of Immunology 169 (1), 507-514, 2002 | 307 | 2002 |
| Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt‐induced signaling protein 1 AB Blom, SM Brockbank, PL van Lent, HM van Beuningen, J Geurts, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 300 | 2009 |
| Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity EN Blaney Davidson, A Scharstuhl, EL Vitters, PM Van Der Kraan, ... Arthritis research & therapy 7, 1-10, 2005 | 288 | 2005 |
| Linkage of chondroitin-sulfate to type I collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro JLC van Susante, J Pieper, P Buma, TH van Kuppevelt, H van Beuningen, ... Biomaterials 22 (17), 2359-2369, 2001 | 273 | 2001 |
| Expression of transforming growth factor-β (TGFβ) and the TGFβ signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation … ENB Davidson, EL Vitters, PM Van Der Kraan, WB Van Den Berg Annals of the rheumatic diseases 65 (11), 1414-1421, 2006 | 269 | 2006 |
| Pralnacasan, an inhibitor of interleukin-1β converting enzyme, reduces joint damage in two murine models of osteoarthritis K Rudolphi, N Gerwin, N Verzijl, P van der Kraan, W Van Den Berg Osteoarthritis and Cartilage 11 (10), 738-746, 2003 | 267 | 2003 |
