| Translating the role of osteogenic-angiogenic coupling in bone formation: Highly efficient chitosan-pDNA activated scaffolds can accelerate bone regeneration in critical-sized … RM Raftery, IM Castaño, G Chen, B Cavanagh, B Quinn, CM Curtin, ... Biomaterials 149, 116-127, 2017 | 122 | 2017 |
| Delivering nucleic‐acid based nanomedicines on biomaterial scaffolds for orthopedic tissue repair: Challenges, progress and future perspectives RM Raftery, DP Walsh, IM Castaño, A Heise, GP Duffy, SA Cryan, ... Advanced Materials 28 (27), 5447-5469, 2016 | 106 | 2016 |
| Next generation bone tissue engineering: non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis I Mencía Castaño, CM Curtin, GP Duffy, FJ O’Brien Scientific Reports 6 (1), 27941, 2016 | 94 | 2016 |
| A novel collagen-nanohydroxyapatite microRNA-activated scaffold for tissue engineering applications capable of efficient delivery of both miR-mimics and antagomiRs to human … IM Castaño, CM Curtin, G Shaw, JM Murphy, GP Duffy, FJ O'Brien Journal of controlled release 200, 42-51, 2015 | 92 | 2015 |
| Delivery of the improved BMP-2-Advanced plasmid DNA within a gene-activated scaffold accelerates mesenchymal stem cell osteogenesis and critical size defect repair RM Raftery, I Mencía-Castaño, S Sperger, G Chen, B Cavanagh, ... Journal of controlled release 283, 20-31, 2018 | 77 | 2018 |
| Scaffold‐based microRNA therapies in regenerative medicine and cancer CM Curtin, IM Castaño, FJ O'Brien Advanced healthcare materials 7 (1), 1700695, 2018 | 68 | 2018 |
| Highly versatile cell-penetrating peptide loaded scaffold for efficient and localised gene delivery to multiple cell types: From development to application in tissue engineering RM Raftery, DP Walsh, LB Ferreras, IM Castaño, G Chen, M LeMoine, ... Biomaterials 216, 119277, 2019 | 56 | 2019 |
| Harnessing an inhibitory role of miR-16 in osteogenesis by human mesenchymal stem cells for advanced scaffold-based bone tissue engineering I Mencía Castaño, CM Curtin, GP Duffy, FJ O'Brien Tissue Engineering Part A 25 (1-2), 24-33, 2019 | 41 | 2019 |
| Rapid bone repair with the recruitment of CD206+ M2-like macrophages using non-viral scaffold-mediated miR-133a inhibition of host cells IM Castaño, RM Raftery, G Chen, B Cavanagh, B Quinn, GP Duffy, ... Acta biomaterialia 109, 267-279, 2020 | 37 | 2020 |
| Nanoparticle-mediated siRNA delivery assessed in a 3D co-culture model simulating prostate cancer bone metastasis KA Fitzgerald, J Guo, RM Raftery, IM Castano, CM Curtin, M Gooding, ... International journal of pharmaceutics 511 (2), 1058-1069, 2016 | 35 | 2016 |
| Transfection of autologous host cells in vivo using gene activated collagen scaffolds incorporating star-polypeptides DP Walsh, RM Raftery, IM Castaño, R Murphy, B Cavanagh, A Heise, ... Journal of controlled release 304, 191-203, 2019 | 33 | 2019 |
| Collagen/GAG scaffolds activated by RALA-siMMP-9 complexes with potential for improved diabetic foot ulcer healing LP Yan, IM Castano, R Sridharan, D Kelly, M Lemoine, BL Cavanagh, ... Materials Science and Engineering: C 114, 111022, 2020 | 24 | 2020 |
| microRNA modulation I Mencía Castaño, RM Raftery, CM Curtin, J Grillari, H Redl, FJ O’Brien Cell Engineering and Regeneration, 511-576, 2020 | 6 | 2020 |
| Dual scaffold delivery of miR-210 mimic and miR-16 inhibitor enhances angiogenesis and osteogenesis to accelerate bone healing IM Castaño, RM Raftery, G Chen, B Cavanagh, B Quinn, GP Duffy, ... Acta Biomaterialia 172, 480-493, 2023 | 4 | 2023 |
| COUPLING ANGIOGENESIS AND OSTEOGENESIS FOR ENHANCED IN VIVO BONE REPAIR USING SCAFFOLDS AND COMBINATORIAL MICRORNA THERAPY CM Curtin, IM Castano, RM Raftery, G Chen, B Cavanagh, B Quinn, ... TISSUE ENGINEERING PART A 28, S456-S456, 2022 | | 2022 |
| Corrigendum to" Transfection of autologous host cells in vivo using gene activated collagen scaffolds incorporating star-polypeptides"[J. Control. Release 304 (2019) 191-203] DP Walsh, RM Raftery, IM Castaño, R Murphy, B Cavanagh, A Heise, ... Journal of controlled release: official journal of the Controlled Release …, 2020 | | 2020 |
| Development of a microRNA Delivery Scaffold System for Bone Tissue Engineering IM Castaño Royal College of Surgeons in Ireland, 2015 | | 2015 |
| Nanohydroxyapatite-based microRNA delivery on Collagen-nanohydroxyapatite Scaffolds for Bone Tissue Engineering I Mencía Castaño, CM Curtin, GP Duffy, FJ O’Brien | | |
