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Helena Cocheme
Helena Cocheme
MRC London Institute of Medical Sciences, Imperial College London
Verified email at lms.mrc.ac.uk - Homepage
Title
Cited by
Cited by
Year
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism
F Cabreiro, C Au, KY Leung, N Vergara-Irigaray, HM Cochemé, T Noori, ...
Cell 153 (1), 228-239, 2013
8232013
Complex I is the major site of mitochondrial superoxide production by paraquat
HM Cochemé, MP Murphy
Journal of biological chemistry 283 (4), 1786-1798, 2008
6042008
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I
ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ...
Nature medicine 19 (6), 753-759, 2013
5732013
Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology
MF Ross, GF Kelso, FH Blaikie, AM James, HM Cocheme, A Filipovska, ...
Biochemistry (Moscow) 70 (2), 222-230, 2005
5062005
Mitochondrial pharmacology
RAJ Smith, RC Hartley, HM Cocheme, MP Murphy
Trends in pharmacological sciences 33 (6), 341-352, 2012
4752012
Interactions of Mitochondria-targeted and Untargeted Ubiquinones with the Mitochondrial Respiratory Chain and Reactive Oxygen Species: IMPLICATIONS FOR THE USE OF EXOGENOUS …
AM James, HM Cochemé, RAJ Smith, MP Murphy
Journal of Biological Chemistry 280 (22), 21295-21312, 2005
4162005
Mitochondria-Targeted Antioxidant MitoQ10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy
D Graham, NN Huynh, CA Hamilton, E Beattie, RAJ Smith, HM Cochemé, ...
Hypertension 54 (2), 322-328, 2009
3622009
Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from …
MP Murphy, KS Echtay, FH Blaikie, J Asin-Cayuela, HM Cochemé, ...
Journal of Biological Chemistry 278 (49), 48534-48545, 2003
3522003
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix
HM Cochemé, C Quin, SJ McQuaker, F Cabreiro, A Logan, TA Prime, ...
Cell metabolism 13 (3), 340-350, 2011
3032011
Mitochondrial redox signalling at a glance
Y Collins, ET Chouchani, AM James, KE Menger, HM Cochemé, ...
Journal of cell science 125 (4), 801-806, 2012
2832012
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice
S Rodriguez-Cuenca, HM Cochemé, A Logan, I Abakumova, TA Prime, ...
Free Radical Biology and Medicine 48 (1), 161-172, 2010
2142010
Oxidative stress and life histories: unresolved issues and current needs
JR Speakman, JD Blount, AM Bronikowski, R Buffenstein, C Isaksson, ...
Ecology and Evolution 5 (24), 5745-5757, 2015
1782015
Mitochondrial targeting of quinones: therapeutic implications
HM Cochemé, GF Kelso, AM James, MF Ross, J Trnka, T Mahendiran, ...
Mitochondrion 7, S94-S102, 2007
1502007
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy
R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ...
Cell 178 (6), 1299-1312. e29, 2019
1422019
Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction
KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ...
Brain 138 (7), 1801-1816, 2015
1412015
Mitochondria‐targeted antioxidants in the treatment of disease
RAJ Smith, VJ Adlam, FH Blaikie, ARB Manas, CM Porteous, AM James, ...
Annals of the New York Academy of Sciences 1147 (1), 105-111, 2008
1282008
Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila
HM Cochemé, A Logan, TA Prime, I Abakumova, C Quin, SJ McQuaker, ...
Nature protocols 7 (5), 946-958, 2012
1212012
Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling
N Alic, TD Andrews, ME Giannakou, I Papatheodorou, C Slack, ...
Molecular systems biology 7 (1), 502, 2011
1202011
Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat
EL Robb, JM Gawel, D Aksentijević, HM Cochemé, TS Stewart, ...
Free Radical Biology and Medicine 89, 883-894, 2015
1092015
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease
F Kerr, O Sofola-Adesakin, DK Ivanov, J Gatliff, B Gomez Perez-Nievas, ...
PLoS genetics 13 (3), e1006593, 2017
1062017
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