Marco Sciacovelli
Marco Sciacovelli
Department of Molecular and Clinical Cancer Medicine-University of Liverpool
Verified email at - Homepage
Cited by
Cited by
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonšalves, TI Johnson, VR Zecchini, ASH Da Costa, ...
Nature 537 (7621), 544-547, 2016
Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition
A Rasola, M Sciacovelli, F Chiara, B Pantic, WS Brusilow, P Bernardi
Proceedings of the National Academy of Sciences 107 (2), 726-731, 2010
Fumarate induces redox-dependent senescence by modifying glutathione metabolism
L Zheng, S Cardaci, L Jerby, ED MacKenzie, M Sciacovelli, TI Johnson, ...
Nature communications 6 (1), 6001, 2015
The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase
M Sciacovelli, G Guzzo, V Morello, C Frezza, L Zheng, N Nannini, ...
Cell metabolism 17 (6), 988-999, 2013
Metabolic reprogramming and epithelial‐to‐mesenchymal transition in cancer
M Sciacovelli, C Frezza
The FEBS journal 284 (19), 3132-3144, 2017
Signal transduction to the permeability transition pore
A Rasola, M Sciacovelli, B Pantic, P Bernardi
FEBS letters 584 (10), 1989-1996, 2010
Oncometabolites: Unconventional triggers of oncogenic signalling cascades
M Sciacovelli, C Frezza
Free Radical Biology and Medicine 100, 175-181, 2016
Germline FH Mutations Presenting With Pheochromocytoma
GR Clark, M Sciacovelli, E Gaude, DM Walsh, G Kirby, MA Simpson, ...
The Journal of Clinical Endocrinology & Metabolism 99 (10), E2046-E2050, 2014
The metabolic alterations of cancer cells
M Sciacovelli, E Gaude, M Hilvo, C Frezza
Methods in enzymology 542, 1-23, 2014
Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3α/β and Bax, leading to permeability transition pore opening and tumor cell death
F Chiara, A Gambalunga, M Sciacovelli, A Nicolli, L Ronconi, D Fregona, ...
Cell death & disease 3 (12), e444-e444, 2012
Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells
G Guzzo, M Sciacovelli, P Bernardi, A Rasola
Oncotarget 5 (23), 11897, 2014
Fumarate hydratase in cancer: A multifaceted tumour suppressor
C Schmidt, M Sciacovelli, C Frezza
Seminars in cell & developmental biology 98, 15-25, 2020
Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses
A Dugourd, C Kuppe, M Sciacovelli, E Gjerga, A Gabor, KB Emdal, ...
Molecular systems biology 17 (1), e9730, 2021
Fumarate hydratase loss causes combined respiratory chain defects
PA Tyrakis, ME Yurkovich, M Sciacovelli, EK Papachristou, HR Bridges, ...
Cell reports 21 (4), 1036-1047, 2017
Antamanide, a derivative of Amanita phalloides, is a novel inhibitor of the mitochondrial permeability transition pore
L Azzolin, N Antolini, A Calderan, P Ruzza, M Sciacovelli, O Marin, ...
PloS one 6 (1), e16280, 2011
SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I
F Ciscato, M Sciacovelli, G Villano, C Turato, P Bernardi, A Rasola, ...
Oncotarget 5 (9), 2418, 2014
Mutations in mitochondrial DNA causing tubulointerstitial kidney disease
TM Connor, S Hoer, A Mallett, DP Gale, A Gomez-Duran, V Posse, ...
PLoS genetics 13 (3), e1006620, 2017
Metabolic drivers in hereditary cancer syndromes
M Sciacovelli, C Schmidt, ER Maher, C Frezza
Annual Review of Cancer Biology 4, 77-97, 2020
Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells
E Gonšalves, M Sciacovelli, ASH Costa, MGB Tran, TI Johnson, ...
Metabolic engineering 45, 149-157, 2018
Fumarate drives EMT in renal cancer
M Sciacovelli, C Frezza
Cell Death and Differentiation 24 (1), 1, 2017
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