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Paul D Wes
Paul D Wes
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TRPC1, a human homolog of a Drosophila store-operated channel.
PD Wes, J Chevesich, A Jeromin, C Rosenberg, G Stetten, C Montell
Proceedings of the National Academy of Sciences 92 (21), 9652-9656, 1995
8041995
Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
TF Galatro, IR Holtman, AM Lerario, ID Vainchtein, N Brouwer, PR Sola, ...
Nature neuroscience 20 (8), 1162-1171, 2017
6462017
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
IR Holtman, DD Raj, JA Miller, W Schaafsma, Z Yin, N Brouwer, PD Wes, ...
Acta neuropathologica communications 3, 1-18, 2015
5712015
Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer’s disease model
M Kitazawa, D Cheng, MR Tsukamoto, MA Koike, PD Wes, V Vasilevko, ...
The Journal of Immunology 187 (12), 6539-6549, 2011
4812011
Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
AJ Whitworth, DA Theodore, JC Greene, H Beneš, PD Wes, LJ Pallanck
Proceedings of the National Academy of Sciences 102 (22), 8024-8029, 2005
4672005
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson’s disease
M Meulener, AJ Whitworth, CE Armstrong-Gold, P Rizzu, P Heutink, ...
Current Biology 15 (17), 1572-1577, 2005
4092005
C. elegans odour discrimination requires asymmetric diversity in olfactory neurons
PD Wes, CI Bargmann
Nature 410 (6829), 698-701, 2001
2812001
CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease
SH Cho, B Sun, Y Zhou, TM Kauppinen, B Halabisky, P Wes, ...
Journal of Biological Chemistry 286 (37), 32713-32722, 2011
2782011
Targeting microglia for the treatment of Alzheimer's Disease
PD Wes, FA Sayed, F Bard, L Gan
Glia 64 (10), 1710-1732, 2016
1872016
Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease
K Trinh, K Moore, PD Wes, PJ Muchowski, J Dey, L Andrews, LJ Pallanck
Journal of Neuroscience 28 (2), 465-472, 2008
1772008
Critical data‐based re‐evaluation of minocycline as a putative specific microglia inhibitor
T Möller, F Bard, A Bhattacharya, K Biber, B Campbell, E Dale, C Eder, ...
Glia 64 (10), 1788-1794, 2016
1642016
Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease
PD Wes, IR Holtman, EWGM Boddeke, T Möller, BJL Eggen
Glia 64 (2), 197-213, 2016
1542016
Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models
S Sankaranarayanan, DM Barten, L Vana, N Devidze, L Yang, ...
PloS one 10 (5), e0125614, 2015
1522015
Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD
PD Wes, XZS Xu, HS Li, F Chien, SK Doberstein, C Montell
Nature neuroscience 2 (5), 447-453, 1999
1461999
Drosophila models pioneer a new approach to drug discovery for Parkinson's disease
AJ Whitworth, PD Wes, LJ Pallanck
Drug discovery today 11 (3-4), 119-126, 2006
1432006
Retinal targets for calmodulin include proteins implicated in synaptic transmission
XZS Xu, PD Wes, H Chen, HS Li, M Yu, S Morgan, Y Liu, C Montell
Journal of Biological Chemistry 273 (47), 31297-31307, 1998
1221998
Transient receptor potential protein subunit assembly and membrane distribution in human platelets
SL Brownlow, SO Sage
Thrombosis and haemostasis 94 (10), 839-845, 2005
1132005
Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer’s disease
PD Wes, A Easton, J Corradi, DM Barten, N Devidze, LB DeCarr, ...
PloS one 9 (8), e106050, 2014
1072014
Tau transgenic mice as models for cerebrospinal fluid tau biomarkers
DM Barten, GW Cadelina, N Hoque, LB DeCarr, VL Guss, L Yang, ...
Journal of Alzheimer's Disease 24 (s2), 127-141, 2011
1032011
RIC, a calmodulin‐binding Ras‐like GTPase.
PD Wes, M Yu, C Montell
The EMBO journal 15 (21), 5839-5848, 1996
1021996
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Artikelen 1–20