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Nestor Molfino
Nestor Molfino
Global Development Lead at Amgen
Geverifieerd e-mailadres voor Amgen.com - Homepage
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MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function
R Kolbeck, A Kozhich, M Koike, L Peng, CK Andersson, MM Damschroder, ...
Journal of Allergy and Clinical Immunology 125 (6), 1344-1353. e2, 2010
6452010
Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study
M Castro, SE Wenzel, ER Bleecker, E Pizzichini, P Kuna, WW Busse, ...
The Lancet Respiratory Medicine 2 (11), 879-890, 2014
5622014
Effect of low concentrations of ozone on inhaled allergen responses in asthmatic subjects
NA Molfino, SC Wright, I Katz, S Tarlo, F Silverman, PA McClean, ...
The Lancet 338 (8761), 199-203, 1991
5191991
Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia
M Laviolette, DL Gossage, G Gauvreau, R Leigh, R Olivenstein, R Katial, ...
Journal of allergy and clinical immunology 132 (5), 1086-1096. e5, 2013
5032013
A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma
E Piper, C Brightling, R Niven, C Oh, R Faggioni, K Poon, D She, C Kell, ...
European Respiratory Journal 41 (2), 330-338, 2013
4232013
Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma
WW Busse, R Katial, D Gossage, S Sari, B Wang, R Kolbeck, AJ Coyle, ...
Journal of Allergy and Clinical Immunology 125 (6), 1237-1244. e2, 2010
3962010
Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma
CK Oh, GP Geba, N Molfino
European Respiratory Review 19 (115), 46-54, 2010
3282010
Respiratory arrest in near-fatal asthma
NA Molfino, LJ Nannini, AN Martelli, AS Slutsky
New England Journal of Medicine 324 (5), 285-288, 1991
2871991
Molecular and clinical rationale for therapeutic targeting of interleukin‐5 and its receptor
NA Molfino, D Gossage, R Kolbeck, JM Parker, GP Geba
Clinical & Experimental Allergy 42 (5), 712-737, 2012
2502012
Genetics of COPD
NA Molfino
Chest 125 (5), 1929-1940, 2004
2102004
A randomized trial of benralizumab, an antiinterleukin 5 receptor α monoclonal antibody, after acute asthma
RM Nowak, JM Parker, RA Silverman, BH Rowe, H Smithline, F Khan, ...
The American journal of emergency medicine 33 (1), 14-20, 2015
2042015
Effect of tezepelumab on airway inflammatory cells, remodelling, and hyperresponsiveness in patients with moderate-to-severe uncontrolled asthma (CASCADE): a double-blind …
S Diver, L Khalfaoui, C Emson, SE Wenzel, A Menzies-Gow, ME Wechsler, ...
The Lancet Respiratory Medicine 9 (11), 1299-1312, 2021
1822021
Use of intravenous pulsed cyclophosphamide in severe, generalized myasthenia gravis
L Gustavo De Feo, J Schottlender, NA Martelli, NA Molfino
Muscle & Nerve: Official Journal of the American Association of …, 2002
1822002
Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in …
JM Parker, CK Oh, C LaForce, SD Miller, DS Pearlman, C Le, GJ Robbie, ...
BMC pulmonary medicine 11, 1-10, 2011
1642011
A randomized, controlled trial to evaluate the effect of an anti-interleukin-9 monoclonal antibody in adults with uncontrolled asthma
CK Oh, R Leigh, KK McLaurin, K Kim, M Hultquist, NA Molfino
Respiratory research 14, 1-11, 2013
1372013
Smoking and idiopathic pulmonary fibrosis
CK Oh, LA Murray, NA Molfino
Pulmonary medicine 2012, 2012
1232012
Cardiovascular safety of high doses of inhaled fenoterol and albuterol in acute severe asthma
MT Newhouse, KR Chapman, AL McCallum, RT Abboud, DM Bowie, ...
Chest 110 (3), 595-603, 1996
1121996
Assessment of airway tone in asthma
NA Molfino, AS Slutsky, G Julia-Serda, V Hoffstein, JP Szalai, ...
Am Rev Respir Dis 148, 1238-1243, 1993
1021993
Treatment of acute severe asthma with inhaled albuterol delivered via jet nebulizer, metered dose inhaler with spacer, or dry powder
AC Raimondi, J Schottlender, D Lombardi, NA Molfino
Chest 112 (1), 24-28, 1997
1011997
The impact of exacerbation frequency on mortality following acute exacerbations of COPD: a registry-based cohort study
SAJ Schmidt, MB Johansen, M Olsen, X Xu, JM Parker, NA Molfino, ...
BMJ open 4 (12), e006720, 2014
982014
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