Functional mapping and annotation of genetic associations with FUMA K Watanabe, E Taskesen, A Van Bochoven, D Posthuma Nature communications 8 (1), 1826, 2017 | 3099 | 2017 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 657 | 2019 |
Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence S Sniekers, S Stringer, K Watanabe, PR Jansen, JRI Coleman, E Krapohl, ... Nature genetics 49 (7), 1107-1112, 2017 | 589 | 2017 |
Prognostic impact, concurrent genetic mutations, and gene expression features of AML with CEBPA mutations in a cohort of 1182 cytogenetically normal AML patients: further … E Taskesen, L Bullinger, A Corbacioglu, MA Sanders, CAJ Erpelinck, ... Blood, The Journal of the American Society of Hematology 117 (8), 2469-2475, 2011 | 454 | 2011 |
Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits AR Hammerschlag, S Stringer, CA De Leeuw, S Sniekers, E Taskesen, ... Nature genetics 49 (11), 1584-1592, 2017 | 300 | 2017 |
Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts R Horos, H IJspeert, D Pospisilova, R Sendtner, C Andrieu-Soler, ... Blood, The Journal of the American Society of Hematology 119 (1), 262-272, 2012 | 212 | 2012 |
The value of allogeneic and autologous hematopoietic stem cell transplantation in prognostically favorable acute myeloid leukemia with double mutant CEBPA RF Schlenk, E Taskesen, Y van Norden, J Krauter, A Ganser, L Bullinger, ... Blood, The Journal of the American Society of Hematology 122 (9), 1576-1582, 2013 | 178 | 2013 |
Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells LL Smith, J Yeung, BB Zeisig, N Popov, I Huijbers, J Barnes, AJ Wilson, ... Cell stem cell 8 (6), 649-662, 2011 | 146 | 2011 |
MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1–regulated pathways in mice A Meenhuis, PA van Veelen, H de Looper, N van Boxtel, IJ van den Berge, ... Blood, The Journal of the American Society of Hematology 118 (4), 916-925, 2011 | 118 | 2011 |
EVI1 is critical for the pathogenesis of a subset of MLL-AF9–rearranged AMLs EMJ Bindels, M Havermans, S Lugthart, C Erpelinck, E Wocjtowicz, ... Blood, The Journal of the American Society of Hematology 119 (24), 5838-5849, 2012 | 97 | 2012 |
An epigenome-wide association study meta-analysis of educational attainment R Karlsson Linnér, RE Marioni, CA Rietveld, AJ Simpkin, NM Davies, ... Molecular psychiatry 22 (12), 1680-1690, 2017 | 91 | 2017 |
High levels of canonical Wnt signaling lead to loss of stemness and increased differentiation in hematopoietic stem cells F Famili, MH Brugman, E Taskesen, BEA Naber, R Fodde, FJT Staal Stem Cell Reports 6 (5), 652-659, 2016 | 76 | 2016 |
Functional mapping and annotation of genetic associations with FUMA. Nat. Commun. 8, 1826 K Watanabe, E Taskesen, A Van Bochoven, D Posthuma | 70 | 2017 |
Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling E Taskesen, M Havermans, K van Lom, MA Sanders, Y van Norden, ... Blood, The Journal of the American Society of Hematology 123 (21), 3327-3335, 2014 | 68 | 2014 |
Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia A Zebisch, A Wölfler, I Fried, O Wolf, K Lind, C Bodner, M Haller, ... Leukemia 26 (8), 1842-1849, 2012 | 50 | 2012 |
2D representation of transcriptomes by t-SNE exposes relatedness between human tissues E Taskesen, MJT Reinders PloS one 11 (2), e0149853, 2016 | 49 | 2016 |
van der Poel-van de Luytgaarde E Taskesen, L Bullinger, A Corbacioglu, MA Sanders, CA Erpelinck, ... SC, Damm, F., Krauter, J., Ganser, A., Schlenk, RF, Lowenberg, B., Delwel, R …, 2011 | 41 | 2011 |
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS E Taskesen, A Mishra, S van der Sluis, R Ferrari, JH Veldink, MA Van Es, ... Scientific reports 7 (1), 8899, 2017 | 40 | 2017 |
Pan-cancer subtyping in a 2D-map shows substructures that are driven by specific combinations of molecular characteristics E Taskesen, SMH Huisman, A Mahfouz, JH Krijthe, J De Ridder, ... Scientific reports 6 (1), 24949, 2016 | 37 | 2016 |
Integration of gene expression and DNA-methylation profiles improves molecular subtype classification in acute myeloid leukemia E Taskesen, S Babaei, MMJ Reinders, J de Ridder BMC bioinformatics 16, 1-8, 2015 | 34 | 2015 |