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Giovanni Spagnolli
Giovanni Spagnolli
Sibylla Biotech S.p.A.
Verified email at sibyllabiotech.it
Title
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Cited by
Year
Full atomistic model of prion structure and conversion
G Spagnolli, M Rigoli, S Orioli, AM Sevillano, P Faccioli, H Wille, E Biasini, ...
PLoS pathogens 15 (7), e1007864, 2019
1232019
Atomic detail of protein folding revealed by an ab initio reappraisal of circular dichroism
A Ianeselli, S Orioli, G Spagnolli, P Faccioli, L Cupellini, S Jurinovich, ...
Journal of the American Chemical Society 140 (10), 3674-3682, 2018
432018
Pharmacological inactivation of the prion protein by targeting a folding intermediate
G Spagnolli, T Massignan, A Astolfi, S Biggi, M Rigoli, P Brunelli, ...
Communications Biology 4 (1), 62, 2021
392021
All-atom simulations reveal how single-point mutations promote serpin misfolding
F Wang, S Orioli, A Ianeselli, G Spagnolli, S a Beccara, A Gershenson, ...
Biophysical journal 114 (9), 2083-2094, 2018
27*2018
The cellular prion protein beyond prion diseases
G Manni, V Lewis, M Senesi, G Spagnolli, F Fallarino, S Collins, ...
Swiss Medical Weekly 150, w20222, 2020
192020
Modeling PrPSc Generation Through Deformed Templating
G Spagnolli, M Rigoli, G Novi Inverardi, YB Codeseira, E Biasini, ...
Frontiers in bioengineering and biotechnology 8, 590501, 2020
172020
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia
L Pasetto, M Grassano, S Pozzi, S Luotti, E Sammali, A Migazzi, M Basso, ...
Brain 144 (12), 3710-3726, 2021
152021
All-atom simulation of the HET-s prion replication
L Terruzzi, G Spagnolli, A Boldrini, JR Requena, E Biasini, P Faccioli
PLOS Computational Biology 16 (9), e1007922, 2020
122020
The Compelling Demand for an Effective PrPC-Directed Therapy against Prion Diseases
A Astolfi, G Spagnolli, E Biasini, ML Barreca
ACS Medicinal Chemistry Letters 11 (11), 2063-2067, 2020
112020
Understanding prion structure and conversion
G Spagnolli, JR Requena, E Biasini
Progress in Molecular Biology and Translational Science 175, 19-30, 2020
102020
Ok google, how could i design therapeutics against prion diseases?
M Rigoli, G Spagnolli, P Faccioli, JR Requena, E Biasini
Current opinion in pharmacology 44, 39-45, 2019
92019
Antimalarial Artefenomel Inhibits Human SARS-CoV-2 Replication in Cells while Suppressing the Receptor ACE2
T Massignan, A Boldrini, L Terruzzi, G Spagnolli, A Astolfi, V Bonaldo, ...
arXiv preprint arXiv:2004.13493, 2020
72020
Structural features of an infectious recombinant PrPSc prion using solid state NMR
M Martín-Pastor, YB Codeseira, G Spagnolli, H Eraña, LC Fernández, ...
bioRxiv, 2020.04. 08.032839, 2020
42020
Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin
K Kihn, E Marchiori, G Spagnolli, A Boldrini, L Terruzzi, DA Lawrence, ...
Journal of Biological Chemistry 298 (12), 2022
3*2022
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency
M Rigoli, G Spagnolli, G Lorengo, P Monti, R Potestio, E Biasini, A Inga
International Journal of Molecular Sciences 23 (14), 7960, 2022
22022
Solid state NMR reveals a parallel in register architecture for an infectious recombinant prion
M Martín-Pastor, YB Codeseira, G Spagnolli, H Eraña, LC Fernández, ...
bioRxiv, 2021.07. 20.453078, 2021
22021
All-atom calculation of protein free-energy profiles
S Orioli, A Ianeselli, G Spagnolli, P Faccioli
The Journal of Chemical Physics 147 (15), 2017
22017
Identification of the zebrafish homologues of IMPG2, a retinal proteoglycan
ME Castellini, G Spagnolli, L Poggi, E Biasini, S Casarosa, A Messina
Cell and Tissue Research 394 (1), 93-105, 2023
12023
Folding, Misfolding and Therapeutics in Prion Diseases
G Spagnolli
Università degli studi di Trento, 2021
2021
Characterization of the Zebrafish Homologues of Impg2, a Retinal Proteoglycan Impg2 Characterization in the Zebrafish Retina
S Casarosa, ME Castellini, G Spagnolli, L Poggi, E Biasini, A Messina
Available at SSRN 4045460, 0
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