| Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor JTB Crawley, R de Groot, Y Xiang, BM Luken, DA Lane Blood, The Journal of the American Society of Hematology 118 (12), 3212-3221, 2011 | 299 | 2011 |
| High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women HM Andersson, B Siegerink, BM Luken, JTB Crawley, A Algra, DA Lane, ... Blood, The Journal of the American Society of Hematology 119 (6), 1555-1560, 2012 | 159 | 2012 |
| An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF W Pos, JTB Crawley, R Fijnheer, J Voorberg, DA Lane, BM Luken Blood, The Journal of the American Society of Hematology 115 (8), 1640-1649, 2010 | 144 | 2010 |
| Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation G Marsman, S Zeerleder, BM Luken Cell death & disease 7 (12), e2518-e2518, 2016 | 130 | 2016 |
| The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura BM Luken, EAM Turenhout, JJJ Hulstein, JA Van Mourik, R Fijnheer, ... Thrombosis and haemostasis 93 (02), 267-283, 2005 | 125 | 2005 |
| Conformational activation of ADAMTS13 K South, BM Luken, JTB Crawley, R Phillips, M Thomas, RF Collins, ... Proceedings of the National Academy of Sciences 111 (52), 18578-18583, 2014 | 110 | 2014 |
| Multiple B‐cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type‐1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic … BM Luken, PHP Kaijen, EAM Turenhout, JA Kremer Hovinga, ... Journal of thrombosis and haemostasis 4 (11), 2355-2364, 2006 | 81 | 2006 |
| Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura R Froehlich-Zahnd, JN George, SK Vesely, DR Terrell, K Aboulfatova, ... Haematologica 97 (2), 297, 2012 | 75 | 2012 |
| VH1‐69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura W Pos, BM Luken, JA Kremer Hovinga, EAM Turenhout, F Scheiflinger, ... Journal of thrombosis and haemostasis 7 (3), 421-428, 2009 | 75 | 2009 |
| Autoregulation of von Willebrand factor function by a disulfide bond switch D Butera, F Passam, L Ju, KM Cook, H Woon, C Aponte-Santamaría, ... Science advances 4 (2), eaaq1477, 2018 | 74 | 2018 |
| Amino acid regions 572–579 and 657–666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP BM Luken, EAM Turenhout, PHP Kaijen, MJ Greuter, W Pos, ... Thrombosis and haemostasis 96 (09), 295-301, 2006 | 70 | 2006 |
| Amino acid regions 572–579 and 657–666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP BM Luken, EAM Turenhout, PHP Kaijen, MJ Greuter, W Pos, ... Thrombosis and haemostasis 96 (09), 295-301, 2006 | 70 | 2006 |
| The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function BM Luken, LYN Winn, J Emsley, DA Lane, JTB Crawley Blood, The Journal of the American Society of Hematology 115 (23), 4910-4913, 2010 | 57 | 2010 |
| Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura W Pos, BM Luken, N Sorvillo, JAK Hovinga, J Voorberg Journal of thrombosis and haemostasis 9 (7), 1285-1291, 2011 | 49 | 2011 |
| Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain HM Andersson, MJ Arantes, JTB Crawley, BM Luken, S Tran, B Dahlbäck, ... Blood, The Journal of the American Society of Hematology 115 (23), 4878-4885, 2010 | 45 | 2010 |
| Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice M Heestermans, S Salloum-Asfar, D Salvatori, EH Laghmani, BM Luken, ... Blood, The Journal of the American Society of Hematology 127 (21), 2630-2637, 2016 | 36 | 2016 |
| Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation I Stroo, S Zeerleder, C Ding, BM Luken, JJTH Roelofs, OJ de Boer, ... Thrombosis and Haemostasis 117 (08), 1601-1614, 2017 | 33 | 2017 |
| Differential effects of the loss of intrachain-versus interchain-disulfide bonds in the cystine-knot domain of von Willebrand factor on the clinical phenotype of von Willebrand … P Tjernberg, HL Vos, CC Spaargaren-van Riel, BM Luken, J Voorberg, ... Thrombosis and haemostasis 96 (12), 717-724, 2006 | 30 | 2006 |
| Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF CJ Lynch, DA Lane, BM Luken Blood, The Journal of the American Society of Hematology 123 (16), 2585-2592, 2014 | 25 | 2014 |
| The damage-associated molecular pattern HMGB1 is released early after clinical hepatic ischemia/reperfusion RF van Golen, MJ Reiniers, G Marsman, LK Alles, DM van Rooyen, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (6 …, 2019 | 20 | 2019 |
Wouter PosPhDVerified email at vectorytx.com
