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Brenda Luken
Brenda Luken
Sanquin, Amsterdam
Verified email at sanquin.nl
Title
Cited by
Cited by
Year
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor
JTB Crawley, R de Groot, Y Xiang, BM Luken, DA Lane
Blood, The Journal of the American Society of Hematology 118 (12), 3212-3221, 2011
2992011
High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women
HM Andersson, B Siegerink, BM Luken, JTB Crawley, A Algra, DA Lane, ...
Blood, The Journal of the American Society of Hematology 119 (6), 1555-1560, 2012
1592012
An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF
W Pos, JTB Crawley, R Fijnheer, J Voorberg, DA Lane, BM Luken
Blood, The Journal of the American Society of Hematology 115 (8), 1640-1649, 2010
1442010
Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation
G Marsman, S Zeerleder, BM Luken
Cell death & disease 7 (12), e2518-e2518, 2016
1302016
The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura
BM Luken, EAM Turenhout, JJJ Hulstein, JA Van Mourik, R Fijnheer, ...
Thrombosis and haemostasis 93 (02), 267-283, 2005
1252005
Conformational activation of ADAMTS13
K South, BM Luken, JTB Crawley, R Phillips, M Thomas, RF Collins, ...
Proceedings of the National Academy of Sciences 111 (52), 18578-18583, 2014
1102014
Multiple B‐cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type‐1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic …
BM Luken, PHP Kaijen, EAM Turenhout, JA Kremer Hovinga, ...
Journal of thrombosis and haemostasis 4 (11), 2355-2364, 2006
812006
Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura
R Froehlich-Zahnd, JN George, SK Vesely, DR Terrell, K Aboulfatova, ...
Haematologica 97 (2), 297, 2012
752012
VH1‐69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura
W Pos, BM Luken, JA Kremer Hovinga, EAM Turenhout, F Scheiflinger, ...
Journal of thrombosis and haemostasis 7 (3), 421-428, 2009
752009
Autoregulation of von Willebrand factor function by a disulfide bond switch
D Butera, F Passam, L Ju, KM Cook, H Woon, C Aponte-Santamaría, ...
Science advances 4 (2), eaaq1477, 2018
742018
Amino acid regions 572–579 and 657–666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP
BM Luken, EAM Turenhout, PHP Kaijen, MJ Greuter, W Pos, ...
Thrombosis and haemostasis 96 (09), 295-301, 2006
702006
Amino acid regions 572–579 and 657–666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP
BM Luken, EAM Turenhout, PHP Kaijen, MJ Greuter, W Pos, ...
Thrombosis and haemostasis 96 (09), 295-301, 2006
702006
The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function
BM Luken, LYN Winn, J Emsley, DA Lane, JTB Crawley
Blood, The Journal of the American Society of Hematology 115 (23), 4910-4913, 2010
572010
Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura
W Pos, BM Luken, N Sorvillo, JAK Hovinga, J Voorberg
Journal of thrombosis and haemostasis 9 (7), 1285-1291, 2011
492011
Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain
HM Andersson, MJ Arantes, JTB Crawley, BM Luken, S Tran, B Dahlbäck, ...
Blood, The Journal of the American Society of Hematology 115 (23), 4878-4885, 2010
452010
Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice
M Heestermans, S Salloum-Asfar, D Salvatori, EH Laghmani, BM Luken, ...
Blood, The Journal of the American Society of Hematology 127 (21), 2630-2637, 2016
362016
Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation
I Stroo, S Zeerleder, C Ding, BM Luken, JJTH Roelofs, OJ de Boer, ...
Thrombosis and Haemostasis 117 (08), 1601-1614, 2017
332017
Differential effects of the loss of intrachain-versus interchain-disulfide bonds in the cystine-knot domain of von Willebrand factor on the clinical phenotype of von Willebrand …
P Tjernberg, HL Vos, CC Spaargaren-van Riel, BM Luken, J Voorberg, ...
Thrombosis and haemostasis 96 (12), 717-724, 2006
302006
Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF
CJ Lynch, DA Lane, BM Luken
Blood, The Journal of the American Society of Hematology 123 (16), 2585-2592, 2014
252014
The damage-associated molecular pattern HMGB1 is released early after clinical hepatic ischemia/reperfusion
RF van Golen, MJ Reiniers, G Marsman, LK Alles, DM van Rooyen, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (6 …, 2019
202019
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