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Derek S. Wheeler, MD, MMM, MBA
Derek S. Wheeler, MD, MMM, MBA
Executive Vice President and Chief Medical Officer, Ann & Robert H. Lurie Children's Hospital of
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Year
Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study
SL Weiss, JC Fitzgerald, J Pappachan, D Wheeler, ...
American journal of respiratory and critical care medicine 191 (10), 1147-1157, 2015
5872015
Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock
DS Wheeler, P Devarajan, Q Ma, K Harmon, M Monaco, N Cvijanovich, ...
Critical care medicine 36 (4), 1297, 2008
4202008
Therapeutic hypothermia after out-of-hospital cardiac arrest in children
FW Moler, FS Silverstein, R Holubkov, BS Slomine, JR Christensen, ...
New England Journal of Medicine 372 (20), 1898-1908, 2015
3932015
Sepsis Prevalence, Outcomes, and Therapies (SPROUT) Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Global epidemiology of …
SL Weiss, JC Fitzgerald, J Pappachan, D Wheeler, ...
Am J Respir Crit Care Med 191 (10), 1147-57, 2015
2542015
The host response to sepsis and developmental impact
J Wynn, TT Cornell, HR Wong, TP Shanley, DS Wheeler
Pediatrics 125 (5), 1031-1041, 2010
2412010
Therapeutic hypothermia after in-hospital cardiac arrest in children
FW Moler, FS Silverstein, R Holubkov, BS Slomine, JR Christensen, ...
New England Journal of Medicine 376 (4), 318-329, 2017
2192017
Improving situation awareness to reduce unrecognized clinical deterioration and serious safety events
PW Brady, S Muething, U Kotagal, M Ashby, R Gallagher, D Hall, ...
Pediatrics 131 (1), e298-e308, 2013
1992013
Epigallocatechin-3-gallate, a green tea–derived polyphenol, inhibits IL-1β-dependent proinflammatory signal transduction in cultured respiratory epithelial cells
DS Wheeler, JD Catravas, K Odoms, A Denenberg, V Malhotra, HR Wong
The Journal of nutrition 134 (5), 1039-1044, 2004
1992004
Derivation and validation of the renal angina index to improve the prediction of acute kidney injury in critically ill children
RK Basu, M Zappitelli, L Brunner, Y Wang, HR Wong, LS Chawla, ...
Kidney international 85 (3), 659-667, 2014
1872014
The medicinal chemistry of tea
DS Wheeler, WJ Wheeler
Drug development research 61 (2), 45-65, 2004
1732004
Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4
DS Wheeler, MA Chase, AP Senft, SE Poynter, HR Wong, K Page
Respiratory research 10 (1), 1-13, 2009
1552009
Interleukin-8 as a stratification tool for interventional trials involving pediatric septic shock
HR Wong, N Cvijanovich, DS Wheeler, MT Bigham, M Monaco, K Odoms, ...
American journal of respiratory and critical care medicine 178 (3), 276-282, 2008
1522008
Combining functional and tubular damage biomarkers improves diagnostic precision for acute kidney injury after cardiac surgery
RK Basu, HR Wong, CD Krawczeski, DS Wheeler, PB Manning, ...
Journal of the American College of Cardiology 64 (25), 2753-2762, 2014
1512014
High-reliability emergency response teams in the hospital: improving quality and safety using in situ simulation training
DS Wheeler, G Geis, EH Mack, T LeMaster, MD Patterson
BMJ quality & safety 22 (6), 507-514, 2013
1512013
Admission angiopoietin levels in children with septic shock
JS Giuliano Jr, PM Lahni, K Harmon, HR Wong, LA Doughty, JA Carcillo, ...
Shock (Augusta, Ga.) 28 (6), 650, 2007
1472007
A green tea-derived polyphenol, epigallocatechin-3-gallate, inhibits IκB kinase activation and IL-8 gene expression in respiratory epithelium
PC Chen, DS Wheeler, V Malhotra, K Odoms, AG Denenberg, HR Wong
Inflammation 26 (5), 233-241, 2002
1392002
Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4-and NF-κB-dependent mechanism
MA Chase, DS Wheeler, KM Lierl, VS Hughes, HR Wong, K Page
The Journal of Immunology 179 (9), 6318-6324, 2007
1382007
Critical care delivery: the importance of process of care and ICU structure to improved outcomes: an update from the American College of Critical Care Medicine Task Force on …
BJ Weled, LA Adzhigirey, TM Hodgman, RJ Brilli, A Spevetz, AM Kline, ...
Critical care medicine 43 (7), 1520-1525, 2015
136*2015
Incorporation of biomarkers with the renal angina index for prediction of severe AKI in critically ill children
RK Basu, Y Wang, HR Wong, LS Chawla, DS Wheeler, SL Goldstein
Clinical Journal of the American Society of Nephrology 9 (4), 654-662, 2014
1282014
Quality improvement initiative to reduce serious safety events and improve patient safety culture
SE Muething, A Goudie, PJ Schoettker, LF Donnelly, MA Goodfriend, ...
Pediatrics 130 (2), e423-e431, 2012
1282012
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Articles 1–20