G-Quadruplex-Binding Benzo[a]phenoxazines Down-Regulate c-KIT Expression in Human Gastric Carcinoma Cells KIE McLuckie, ZAE Waller, DA Sanders, D Alves, R Rodriguez, J Dash, ... Journal of the American Chemical Society 133 (8), 2658-2663, 2011 | 182 | 2011 |
G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells KIE McLuckie, M Di Antonio, H Zecchini, J Xian, C Caldas, ... Journal of the American Chemical Society 135 (26), 9640-9643, 2013 | 157 | 2013 |
Reprogramming the mechanism of action of chlorambucil by coupling to a G-quadruplex ligand M Di Antonio, KIE McLuckie, S Balasubramanian Journal of the American Chemical Society 136 (16), 5860-5863, 2014 | 88 | 2014 |
Genotoxicity of the benzene metabolites para-benzoquinone and hydroquinone M Gaskell, KIE McLuckie, PB Farmer Chemico-Biological Interactions 153, 267-270, 2005 | 79 | 2005 |
Targeting a c-MYC G-quadruplex DNA with a fragment library SB HR Nasiri, NM Bell, KIE McLuckie, J Husby, C Abell, S Neidle Chemical Communications 50, 1704-1707, 2014 | 65 | 2014 |
Comparison of the mutagenic activity of the benzene metabolites, hydroquinone and para-benzoquinone in the supF forward mutation assay: a role for minor DNA adducts formed from … M Gaskell, KIE McLuckie, PB Farmer Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 554 (1 …, 2004 | 59 | 2004 |
An acetylene‐bridged 6, 8‐purine dimer as a fluorescent switch‐on probe for parallel G‐quadruplexes M Nikan, M Di Antonio, K Abecassis, K McLuckie, S Balasubramanian Angewandte Chemie International Edition 52 (5), 1428-1431, 2013 | 51 | 2013 |
Comparison of the repair of DNA damage induced by the benzene metabolites hydroquinone and p-benzoquinone: a role for hydroquinone in benzene genotoxicity M Gaskell, KIE McLuckie, PB Farmer Carcinogenesis 26 (3), 673-680, 2005 | 43 | 2005 |
Presence of benzo [a] pyrene diol epoxide adducts in target DNA leads to an increase in UV-induced DNA single strand breaks and supF gene mutations MN Routledge, KIE McLuckie, GDD Jones, PB Farmer, EA Martin Carcinogenesis 22 (8), 1231-1238, 2001 | 33 | 2001 |
Mutagenicity of DNA adducts derived from ethylene oxide exposure in the pSP189 shuttle vector replicated in human Ad293 cells EM Tompkins, KIE McLuckie, DJL Jones, PB Farmer, K Brown Mutation Research/Genetic Toxicology and Environmental Mutagenesis 678 (2 …, 2009 | 30 | 2009 |
DNA adducts formed from 4-hydroxytamoxifen are more mutagenic than those formed by α-acetoxytamoxifen in a shuttle vector target gene replicated in human Ad293 cells KIE McLuckie, MN Routledge, K Brown, M Gaskell, PB Farmer, ... Biochemistry 41 (28), 8899-8906, 2002 | 28 | 2002 |
Mutation Spectra Induced by α-Acetoxytamoxifen− DNA Adducts in Human DNA Repair Proficient and Deficient (Xeroderma Pigmentosum Complementation Group A) Cells KIE McLuckie, RJR Crookston, M Gaskell, PB Farmer, MN Routledge, ... Biochemistry 44 (22), 8198-8205, 2005 | 22 | 2005 |
Mutagenicity of tamoxifen DNA adducts in human endometrial cells and in silico prediction of p53 mutation hotspots E Liapis, KIE McLuckie, PD Lewis, PB Farmer, K Brown Nucleic acids research 36 (18), 5933-5945, 2008 | 11 | 2008 |
Development of a novel site-specific mutagenesis assay using MALDI-ToF MS (SSMA-MS) KIE McLuckie, JH Lamb, JK Sandhu, HL Pearson, K Brown, PB Farmer, ... Nucleic acids research 34 (22), e150-e150, 2006 | 6 | 2006 |
Effects of the order of exposure to a binary mixture of mutagens on the induced mutation spectra in the supF gene KIE McLuckie, M Gaskell, PB Farmer, EA Martin, GDD Jones, ... Mutagenesis 19 (2), 137-141, 2004 | 6 | 2004 |
Selection of appropriate non-clinical animal models to ensure translatability of novel AAV-gene therapies to the clinic M Singh, A Brooks, P Toofan, K McLuckie Gene Therapy 31 (1), 56-63, 2024 | 2 | 2024 |
Mutagenicity of tamoxifen induced DNA damage in human endometrial cells and in silico prediction of p53 mutation hotspots. E Liapis, K McLuckie, P Lewis, P Farmer, K Brown Cancer Research 68 (9_Supplement), 5596-5596, 2008 | 2 | 2008 |
Does UV irradiation of PAH's synergistically increase their genotoxicity? AY Omer, GDD Jones, PB Farmer, KIE McLuckie MUTAGENESIS 22 (6), 449-449, 2007 | | 2007 |
Mutagenicity of tamoxifen-DNA adducts in human endometrial cells and in silico prediction of p53 mutation hotspots E Liapis, PD Lewis, KIE McLuckie, PB Farmer, K Brown MUTAGENESIS 22 (6), 446-447, 2007 | | 2007 |
Weak mutagenicity of DNA adducts derived from ethylene oxide exposure EM Tompkins, DJL Jones, KIE McLuckie, PB Farmer, K Brown Mutagenesis 21 (4), 292-292, 2006 | | 2006 |