Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option WPJ Leenders, B Küsters, K Verrijp, C Maass, P Wesseling, A Heerschap, ... Clinical Cancer Research 10 (18), 6222-6230, 2004 | 240 | 2004 |
Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme JJC Verhoeff, O van Tellingen, A Claes, LJA Stalpers, ME van Linde, ... BMC cancer 9 (1), 1-9, 2009 | 200 | 2009 |
Vessel co-option: how tumors obtain blood supply in the absence of sprouting angiogenesis WPJ Leenders, B Küsters, RMW de Waal Endothelium 9 (2), 83-87, 2002 | 181 | 2002 |
Vascular endothelial growth factor-A165 induces progression of melanoma brain metastases without induction of sprouting angiogenesis B Küsters, WPJ Leenders, P Wesseling, D Smits, K Verrijp, DJ Ruiter, ... Cancer research 62 (2), 341-345, 2002 | 172 | 2002 |
The endogenous anti-angiogenic VEGF isoform, VEGF 165 b inhibits human tumour growth in mice ES Rennel, E Waine, H Guan, Y Schüler, W Leenders, J Woolard, ... British journal of cancer 98 (7), 1250-1257, 2008 | 155 | 2008 |
Glioma: experimental models and reality K Lenting, R Verhaak, M Ter Laan, P Wesseling, W Leenders Acta neuropathologica 133 (2), 263-282, 2017 | 143 | 2017 |
Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization A Claes, P Wesseling, J Jeuken, C Maass, A Heerschap, WPJ Leenders Molecular cancer therapeutics 7 (1), 71-78, 2008 | 112 | 2008 |
Endonexin II, present on human liver plasma membranes, is a specific binding protein of small hepatitis B virus (HBV) envelope protein K Hertogs, WPJ Leenders, E Depla, WCC De Bruin, L Meheus, ... Virology 197 (2), 549-557, 1993 | 112 | 1993 |
Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways A Salikhova, L Wang, AA Lanahan, M Liu, M Simons, WPJ Leenders, ... Circulation research 103 (6), e71-e79, 2008 | 106 | 2008 |
PLEXIN‐D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis B Van Der Zwaag, AJ Hellemons, WPJ Leenders, JPH Burbach, ... Developmental dynamics: an official publication of the American Association …, 2002 | 100 | 2002 |
Differential effects of vascular endothelial growth factor A isoforms in a mouse brain metastasis model of human melanoma B Küsters, RMW de Waal, P Wesseling, K Verrijp, C Maass, A Heerschap, ... Cancer research 63 (17), 5408-5413, 2003 | 97 | 2003 |
Radioprotection of IDH1-mutated cancer cells by the IDH1-mutant inhibitor AGI-5198 RJ Molenaar, D Botman, MA Smits, VV Hira, SA van Lith, J Stap, ... Cancer research 75 (22), 4790-4802, 2015 | 91 | 2015 |
Specific imaging of VEGF‐A expression with radiolabeled anti‐VEGF monoclonal antibody TH Stollman, MGW Scheer, WPJ Leenders, KCN Verrijp, AC Soede, ... International journal of cancer 122 (10), 2310-2314, 2008 | 84 | 2008 |
Phenotypic and genotypic characterization of orthotopic human glioma models and its relevance for the study of anti‐glioma therapy A Claes, J Schuuring, S Boots‐Sprenger, S Hendriks‐Cornelissen, ... Brain pathology 18 (3), 423-433, 2008 | 82 | 2008 |
Imaging liver metastases of colorectal cancer patients with radiolabelled bevacizumab: lack of correlation with VEGF-A expression MGW Scheer, TH Stollman, OC Boerman, K Verrijp, FCGJ Sweep, ... European Journal of Cancer 44 (13), 1835-1840, 2008 | 79 | 2008 |
Increased vascularization predicts favorable outcome in follicular lymphoma A Koster, JHJM van Krieken, MA MacKenzie, M Schraders, GF Borm, ... Clinical cancer research 11 (1), 154-161, 2005 | 78 | 2005 |
Circulating tumour tissue fragments in patients with pulmonary metastasis of clear cell renal cell carcinoma G Kats‐Ugurlu, I Roodink, M de Weijert, D Tiemessen, C Maass, K Verrijp, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 77 | 2009 |
Vascular endothelial growth factor‐A determines detectability of experimental melanoma brain metastasis in GD‐DTPA‐enhanced MRI. W Leenders, B Küsters, J Pikkemaat, P Wesseling, D Ruiter, A Heerschap, ... International journal of cancer 105 (4), 437-443, 2003 | 77 | 2003 |
Targeted therapies of cancer: angiogenesis inhibition seems not enough I Roodink, WPJ Leenders Cancer letters 299 (1), 1-10, 2010 | 75 | 2010 |
Robotic injection of zebrafish embryos for high-throughput screening in disease models HP Spaink, C Cui, MI Wiweger, HJ Jansen, WJ Veneman, R Marín-Juez, ... Methods 62 (3), 246-254, 2013 | 74 | 2013 |