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Ruben de Groen
Ruben de Groen
PhD-student, LUMC
Geverifieerd e-mailadres voor lumc.nl
Titel
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Jaar
IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling
PC Maity, M Bilal, MT Koning, M Young, CAM van Bergen, V Renna, ...
Proceedings of the National Academy of Sciences 117 (8), 4320-4327, 2020
692020
MYD88 in the driver’s seat of B-cell lymphomagenesis: From molecular mechanisms to clinical implications
RAL de Groen, AMR Schrader, MJ Kersten, ST Pals, JSP Vermaat
haematologica 104 (12), 2337, 2019
642019
MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis
JS Vermaat, SF Somers, LC de Wreede, W Kraan, RAL de Groen, ...
Haematologica 105 (2), 424, 2020
612020
Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing
W Arindrarto, DM Borràs, RAL de Groen, RR van den Berg, IJ Locher, ...
Leukemia 35 (1), 47-61, 2021
562021
Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype
RAL de Groen, R van Eijk, S Böhringer, T van Wezel, R Raghoo, D Ruano, ...
Blood advances 5 (19), 3760-3775, 2021
202021
High frequency of inactivating tetraspanin CD37 mutations in diffuse large B-cell lymphoma at immune-privileged sites
S Elfrink, CM de Winde, M van den Brand, M Berendsen, MGM Roemer, ...
Blood, The Journal of the American Society of Hematology 134 (12), 946-950, 2019
182019
Cell-of-origin classification using the Hans and Lymph2Cx algorithms in primary cutaneous large B-cell lymphomas
AMR Schrader, RAL de Groen, R Willemze, PM Jansen, KD Quint, ...
Virchows Archiv, 1-9, 2022
142022
Biological and clinical implications of gene-expression profiling in diffuse large B-cell lymphoma: a proposal for a targeted BLYM-777 consortium panel as part of a …
FA de Groot, RAL de Groen, A van den Berg, PM Jansen, KH Lam, ...
Cancers 14 (8), 1857, 2022
82022
BRAF V600E is associated with higher incidence of second cancers in adults with Langerhans cell histiocytosis
AA Acosta-Medina, PG Kemps, TCE Zondag, JP Abeykoon, J Forma-Borst, ...
Blood 142 (18), 1570-1575, 2023
52023
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic …
E Quinten, JH Sepúlveda-Yáñez, MT Koning, JA Eken, D Pfeifer, ...
Haematologica 109 (3), 824, 2024
32024
Real-world routine diagnostic molecular analysis for TP53 mutational status is recommended over p53 immunohistochemistry in B-cell lymphomas
LM de Haan, RAL de Groen, FA de Groot, T Noordenbos, T van Wezel, ...
Virchows Archiv, 1-12, 2023
32023
Genetic Stability of Driver Alterations in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type and Their Relapses: A Rationale for the Use of Molecular-Based Methods for …
AMR Schrader, RAL de Groen, R Willemze, PM Jansen, KD Quint, ...
Cancers 14 (20), 5152, 2022
32022
High-throughput bcr sequencing and single-cell transcriptomics reveal distinct transcriptional profiles associated with subclonal evolution of follicular lymphoma
CAM van Bergen, MT Koning, E Quinten, A Mykowiecka, J Sepulveda, ...
Blood 134, 298, 2019
32019
Synchronous diffuse large B-cell lymphoma and mantle cell lymphoma: support for low-threshold biopsies and genetic testing
FA de Groot, LM de Haan, RAL de Groen, L Heijmen, T van Wezel, ...
Leukemia & lymphoma 63 (5), 1251-1255, 2022
22022
Sinonasal DLBCL: molecular profiling identifies subtypes with distinctive prognosis and targetable genetic features
PRG Eriksen, F de Groot, E Clasen-Linde, P de Nully Brown, R de Groen, ...
Blood advances, 2024
12024
A significant proportion of classic Hodgkin lymphoma recurrences represents clonally unrelated second primary lymphoma
DAG van Bladel, WBC Stevens, LI Kroeze, RAL de Groen, FA de Groot, ...
Blood Advances 7 (19), 5911-5924, 2023
12023
Special anatomical subtypes of diffuse large B-cell lymphoma have distinct tumor microenvironments
T Noordenbos, FA De Groot, RAL De Groen, LM De Haan, RT Krog, ...
Blood 140 (Supplement 1), 164-165, 2022
12022
Autonomous BCR signaling and genetic aberrations in CLL-phenotype monoclonal B lymphocytosis in siblings of CLL patients
JH Sepulveda Yanez, E Quinten, MT Koning, JA Eken, D Pfeifer, ...
Blood 140 (Supplement 1), 1526-1527, 2022
12022
Consolidation Improves Survival in Primary Central Nervous System Lymphoma without Preference for Type of High-Dose Methotrexate-Based Induction Treatment Regimen
FA De Groot, JK Doorduijn, M Brink, RAL De Groen, LM De Haan, ...
Blood 140 (Supplement 1), 369-371, 2022
12022
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL
JA Eken, MT Koning, K Kupcova, JH Sepúlveda Yáñez, RAL de Groen, ...
Journal of Experimental Medicine 221 (5), 2024
2024
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