A robust model for read count data in exome sequencing experiments and implications for copy number variant calling V Plagnol, J Curtis, M Epstein, K Mok, E Stebbings, S Grigoriadou, ... Bioinformatics, 2012 | 684 | 2012 |
Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA analysis in metastatic breast cancer C Fribbens, IG Murillas, M Beaney, S Hrebien, B O’Leary, L Kilburn, ... Annals of Oncology 29 (1), 145-153, 2018 | 163 | 2018 |
Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA D Gale, ARJ Lawson, K Howarth, M Madi, B Durham, S Smalley, ... PloS one 13 (3), e0194630, 2018 | 150 | 2018 |
Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling V Plagnol, S Woodhouse, K Howarth, S Lensing, M Smith, M Epstein, ... PloS one 13 (3), e0193802, 2018 | 113 | 2018 |
Isolation and comparative transcriptome analysis of human fetal and iPSC-derived cone photoreceptor cells E Welby, J Lakowski, V Di Foggia, D Budinger, A Gonzalez-Cordero, ... Stem Cell Reports 9 (6), 1898-1915, 2017 | 103 | 2017 |
Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods RJM Bashford-Rogers, AL Palser, SF Idris, L Carter, M Epstein, ... BMC immunology 15, 1-9, 2014 | 60 | 2014 |
Bayesian statistical inference in ion-channel models with exact missed event correction M Epstein, B Calderhead, MA Girolami, LG Sivilotti Biophysical journal 111 (2), 333-348, 2016 | 34 | 2016 |
Bayesian approaches for mechanistic ion channel modeling B Calderhead, M Epstein, L Sivilotti, M Girolami In silico systems biology, 247-272, 2013 | 13 | 2013 |
Revealing individual signatures of human T cell CDR3 sequence repertoires with Kidera factors M Epstein, M Barenco, N Klein, M Hubank, RE Callard PLoS One 9 (1), e86986, 2014 | 12 | 2014 |
543 Sensitive quantification and tracking of the active components of a Clonal Neoantigen T cell (cNeT) therapy: From manufacture to peripheral circulation S Turajlic, M Jamal-Hanjani, A Furness, R Plummer, J Cave, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | 1 | 2021 |
Characterization of a novel clonal neoantigen reactive T cell (cNeT) product through a comprehensive translational research program M Epstein, R Pike, E Leire, J Middleton, M Wileman, L Ouboussad, ... Cancer Research 81 (13_Supplement), 1508-1508, 2021 | 1 | 2021 |
SIRPα knockout iPSC-derived macrophages (iMACs) are resistant to CD47-dependent inhibition of phagocytosis and efficiently kill tumor cells in pre-clinical models K Haake, M Mirenda, Q Bernard, P Hublitz, L Gouxette, M Briscadieu, ... Cancer Research 84 (6_Supplement), 5244-5244, 2024 | | 2024 |
Development of innovative off-the-shelf cancer immunotherapies with iPSC-derived CD8-positive T-cells R Tawo, M Mirenda, O Cypris, P Hublitz, N Wagner, M Epstein, ... Cancer Research 84 (6_Supplement), 11-11, 2024 | | 2024 |
427 Development of iPSC-derived cytotoxic CD8+ T-cells as the basis for innovative off-the-shelf cancer immunotherapies R Tawo, F Bertrand, O Cypris, C Beuraud, P Hublitz, P Barron, S Pfänder, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
1515 Gene edited iPSC-derived macrophages (iMACs) show increased phagocytosis in pre-clinical tumor models K Haake, M Mirenda, Q Bernard, P Hublitz, L Gouxette, M Briscadieu, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023 | | 2023 |
193 The Achilles VELOSTM Process 2 boosts the dose of highly functional clonal neoantigen-reactive T cells for precision personalized cell therapies E Kotsiou, J Robinson, A Rogers, D Melandri, A Baker, AR Aragon, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | | 2021 |
Multicentre, prospective research protocol for development of a clonal neoantigen-reactive T cell therapy pipeline across multiple tumour types M Grant, T Hou, F Kyle, FKK Miller, J Robinson, A Rogers, ... HUMAN GENE THERAPY 32 (19-20), A20-A20, 2021 | | 2021 |
Isolating and characterising human cone photoreceptors for cell therapy E Welby, V Di Foggia, J Lakowski, D Budinger, K Kruczek, M Hubank, ... Conference on Changing the Face of Modern Medicine-Stem Cells and Gene Therapy, 2016 | | 2016 |