| OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis TET Mevissen, MK Hospenthal, PP Geurink, PR Elliott, M Akutsu, ... Cell 154 (1), 169-184, 2013 | 576 | 2013 |
| On terminal alkynes that can react with active-site cysteine nucleophiles in proteases R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, PP Geurink, ... Journal of the American Chemical Society, 2013 | 341 | 2013 |
| Chemical Synthesis of Ubiquitin, Ubiquitin‐Based Probes, and Diubiquitin F El Oualid, R Merkx, R Ekkebus, DS Hameed, JJ Smit, A de Jong, ... Angewandte Chemie International Edition 49 (52), 10149-10153, 2010 | 326 | 2010 |
| BAP1/ASXL1 recruitment and activation for H2A deubiquitination DD Sahtoe, WJ Van Dijk, R Ekkebus, H Ovaa, TK Sixma Nature communications 7 (1), 10292, 2016 | 186 | 2016 |
| Recognition of Lys48-linked di-ubiquitin and deubiquitinating activities of the SARS coronavirus papain-like protease M Békés, R Ekkebus, H Ovaa, TT Huang, CD Lima Molecular cell 62 (4), 572-585, 2016 | 137 | 2016 |
| Development of a selective ESI-MS derivatization reagent: synthesis and optimization for the analysis of aldehydes in biological mixtures M Eggink, M Wijtmans, R Ekkebus, H Lingeman, IJP Esch, J Kool, ... Analytical chemistry 80 (23), 9042-9051, 2008 | 125 | 2008 |
| Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G DD Sahtoe, WJ van Dijk, F El Oualid, R Ekkebus, H Ovaa, TK Sixma Molecular cell 57 (5), 887-900, 2015 | 116 | 2015 |
| Non-hydrolyzable diubiquitin probes reveal linkage-specific reactivity of deubiquitylating enzymes mediated by S2 pockets D Flierman, R Ekkebus, PP Geurink, TET Mevissen, MK Hospenthal, ... Cell chemical biology 23 (4), 472-482, 2016 | 107 | 2016 |
| Altered peptide ligands revisited: Vaccine design through chemically modified HLA-A2–restricted T cell epitopes R Hoppes, R Oostvogels, JJ Luimstra, K Wals, M Toebes, L Bies, ... The Journal of Immunology 193 (10), 4803-4813, 2014 | 59 | 2014 |
| Catching a DUB in the act: novel ubiquitin-based active site directed probes R Ekkebus, D Flierman, PP Geurink, H Ovaa Current opinion in chemical biology 23, 63-70, 2014 | 53 | 2014 |
| Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism T van Welsem, T Korthout, R Ekkebus, D Morais, TM Molenaar, ... Nucleic acids research 46 (21), 11251-11261, 2018 | 35 | 2018 |
| Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity RQ Kim, PP Geurink, MPC Mulder, A Fish, R Ekkebus, F El Oualid, ... Nature communications 10 (1), 231, 2019 | 30 | 2019 |
| Technologies for MHC class I immunoproteomics R Hoppes, R Ekkebus, TNM Schumacher, H Ovaa Journal of proteomics 73 (10), 1945-1953, 2010 | 22 | 2010 |
| es, AJ Heck, D. Komander and H. Ovaa R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, PP Geurink, ... J. Am. Chem. Soc 135, 2867-2870, 2013 | 7 | 2013 |
| P. d.; Kool, J.; Niessen, WMA; Irth, H. Development of a Selective ESI-MS Derivatization Reagent: Synthesis and Optimization for the Analysis of Aldehydes in Biological Mixtures M Eggink, M Wijtmans, R Ekkebus, H Lingeman, IJ Esch Anal. Chem 80, 9042-9051, 2008 | 5 | 2008 |
| Cysteine protease capturing agents H Ovaa, R Ekkebus, SI Van Kasteren, A De Jong, PP Geurink US Patent App. 14/412,990, 2015 | 3 | 2015 |
| HLA-A2 M Schumacher, T Mutis, B Rodenko, H Ovaa, E Emmelot, RM Spaapen, ... | | 2014 |
| Non-hydrolyzable protein conjugates, methods and compositions related thereto H Ovaa, A Shanmugham, R Ekkebus, F El Oualid, R Merkx | | 2011 |
| On terminal alkynes that can react with active-site cysteine nucleophiles in proteases–Supplementary Materials R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, AJ Geurink, ... | | |
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