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Jochen Weile
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A reference map of the human binary protein interactome
K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ...
Nature 580 (7803), 402-408, 2020
8012020
Widespread macromolecular interaction perturbations in human genetic disorders
N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ...
Cell 161 (3), 647-660, 2015
5232015
A framework for exhaustively mapping functional missense variants
J Weile, S Sun, AG Cote, J Knapp, M Verby, JC Mellor, Y Wu, C Pons, ...
Molecular systems biology 13 (12), 957, 2017
1562017
MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect
D Esposito, J Weile, J Shendure, LM Starita, AT Papenfuss, FP Roth, ...
Genome biology 20, 1-11, 2019
1342019
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics
N Yachie, E Petsalaki, JC Mellor, J Weile, Y Jacob, M Verby, SB Ozturk, ...
Molecular systems biology 12 (4), 863, 2016
1102016
Multiplexed assays of variant effects contribute to a growing genotype–phenotype atlas
J Weile, FP Roth
Human genetics 137 (9), 665-678, 2018
1042018
Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation
GS Karagiannis, J Weile, GD Bader, J Minta
BMC cardiovascular disorders 13 (1), 1-19, 2013
702013
Improved pathogenicity prediction for rare human missense variants
Y Wu, H Liu, R Li, S Sun, J Weile, FP Roth
The American Journal of Human Genetics 108 (10), 1891-1906, 2021
622021
KeyPathwayMiner: detecting case-specific biological pathways using expression data
N Alcaraz, H Kck, J Weile, A Wipat, J Baumbach
Internet Mathematics 7 (4), 299-313, 2011
552011
An integrated dataset for in silico drug discovery
SJ Cockell, J Weile, P Lord, C Wipat, D Andriychenko, M Pocock, ...
Journal of integrative bioinformatics 7 (3), 15-27, 2010
472010
A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase
S Sun, J Weile, M Verby, Y Wu, Y Wang, AG Cote, I Fotiadou, ...
Genome medicine 12, 1-18, 2020
442020
Systematic analysis of bypass suppression of essential genes
J van Leeuwen, C Pons, G Tan, JZ Wang, J Hou, J Weile, M Gebbia, ...
Molecular systems biology 16 (9), e9828, 2020
332020
Shifting landscapes of human MTHFR missense-variant effects
J Weile, N Kishore, S Sun, R Maaieh, M Verby, R Li, I Fotiadou, ...
The American Journal of Human Genetics 108 (7), 1283-1300, 2021
302021
Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics
JJ Daz‐Meja, A Celaj, JC Mellor, A Cot, A Balint, B Ho, P Bansal, ...
Molecular Systems Biology 14 (5), e7985, 2018
292018
A web application and service for imputing and visualizing missense variant effect maps
Y Wu, J Weile, AG Cote, S Sun, J Knapp, M Verby, FP Roth
Bioinformatics 35 (17), 3191-3193, 2019
182019
Bayesian integration of networks without gold standards
J Weile, K James, J Hallinan, SJ Cockell, P Lord, A Wipat, D Wilkinson
Bioinformatics 28 (11), 1495-1500, 2012
172012
CoryneCenter–An online resource for the integrated analysis of corynebacterial genome and transcriptome data
H Neuweger, J Baumbach, S Albaum, T Bekel, M Dondrup, AT Hser, ...
BMC systems biology 1 (1), 1-12, 2007
152007
MaveRegistry: a collaboration platform for multiplexed assays of variant effect
D Kuang, J Weile, N Kishore, M Nguyen, AF Rubin, S Fields, DM Fowler, ...
Bioinformatics 37 (19), 3382-3383, 2021
142021
Assessing predictions of fitness effects of missense mutations in SUMO‐conjugating enzyme UBE2I
J Zhang, LN Kinch, Q Cong, J Weile, S Sun, AG Cote, FP Roth, NV Grishin
Human mutation 38 (9), 1051-1063, 2017
132017
Prioritizing genes for systematic variant effect mapping
D Kuang, R Truty, J Weile, B Johnson, K Nykamp, C Araya, RL Nussbaum, ...
Bioinformatics 36 (22-23), 5448-5455, 2020
102020
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