Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21 M Cruts, I Gijselinck, J Van Der Zee, S Engelborghs, H Wils, D Pirici, ... Nature 442 (7105), 920-924, 2006 | 1713 | 2006 |
Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study AT van Oosterom, I Judson, J Verweij, S Stroobants, ED di Paola, ... The Lancet 358 (9291), 1421-1423, 2001 | 1595 | 2001 |
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration B Oosthuyse, L Moons, E Storkebaum, H Beck, D Nuyens, K Brusselmans, ... Nature genetics 28 (2), 131-138, 2001 | 1367 | 2001 |
Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease G Van Assche, M Van Ranst, R Sciot, B Dubois, S Vermeire, M Noman, ... New England Journal of Medicine 353 (4), 362-368, 2005 | 1247 | 2005 |
KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours M Debiec-Rychter, R Sciot, A Le Cesne, M Schlemmer, P Hohenberger, ... European journal of cancer 42 (8), 1093-1103, 2006 | 1091 | 2006 |
Consensus meeting for the management of gastrointestinal stromal tumors Report of the GIST Consensus Conference of 20–21 March 2004, under the auspices of ESMO JY Blay, S Bonvalot, P Casali, H Choi, M Debiec-Richter, AP Dei Tos, ... Annals of Oncology 16 (4), 566-578, 2005 | 1014 | 2005 |
The der (17) t (X; 17)(p11; q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25 M Ladanyi, MY Lui, CR Antonescu, A Krause-Boehm, A Meindl, P Argani, ... Oncogene 20 (1), 48-57, 2001 | 640 | 2001 |
Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II … M Debiec-Rychter, H Dumez, I Judson, B Wasag, J Verweij, M Brown, ... European journal of cancer 40 (5), 689-695, 2004 | 596 | 2004 |
Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants M Debiec-Rychter, J Cools, H Dumez, R Sciot, M Stul, N Mentens, ... Gastroenterology 128 (2), 270-279, 2005 | 590 | 2005 |
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome TC Pansuriya, R van Eijk, P d'Adamo, MAJH van Ruler, ML Kuijjer, ... Nature genetics 43 (12), 1256-1261, 2011 | 580 | 2011 |
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein K Spittaels, C Van den Haute, JO Van Dorpe, K Bruynseels, ... The American journal of pathology 155 (6), 2153-2165, 1999 | 468 | 1999 |
Correlation between clinicopathological features and karyotype in lipomatous tumors. A report of 178 cases from the Chromosomes and Morphology (CHAMP) Collaborative Study Group. CD Fletcher, M Akerman, P Dal Cin, I De Wever, N Mandahl, F Mertens, ... The American journal of pathology 148 (2), 623, 1996 | 405 | 1996 |
PRCC-TFE3 renal carcinomas: morphologic, immunohistochemical, ultrastructural, and molecular analysis of an entity associated with the t (X; 1)(p11. 2; q21) P Argani, CR Antonescu, J Couturier, JC Fournet, R Sciot, ... The American journal of surgical pathology 26 (12), 1553-1566, 2002 | 391 | 2002 |
Imatinib mesylate in advanced dermatofibrosarcoma protuberans: pooled analysis of two phase II clinical trials P Rutkowski, M Van Glabbeke, CJ Rankin, W Ruka, BP Rubin, ... Journal of clinical oncology 28 (10), 1772-1779, 2010 | 390 | 2010 |
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization AR Pombo Antunes, I Scheyltjens, F Lodi, J Messiaen, A Antoranz, ... Nature neuroscience 24 (4), 595-610, 2021 | 383 | 2021 |
Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma MR Tanas, A Sboner, AM Oliveira, MR Erickson-Johnson, J Hespelt, ... Science translational medicine 3 (98), 98ra82-98ra82, 2011 | 375 | 2011 |
Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and … M Van Glabbeke, J Verweij, PG Casali, A Le Cesne, P Hohenberger, ... Journal of Clinical Oncology 23 (24), 5795-5804, 2005 | 366 | 2005 |
The development of the intrahepatic bile ducts in man: a keratin‐immunohistochemical study P Van Eyken, R Sciot, F Callea, KVD Steen, P Moerman, VJ Desmet Hepatology 8 (6), 1586-1595, 1988 | 364 | 1988 |
Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate H Prenen, J Cools, N Mentens, C Folens, R Sciot, P Schöffski, ... Clinical Cancer Research 12 (8), 2622-2627, 2006 | 363 | 2006 |
Postoperative adjuvant dendritic cell–based immunotherapy in patients with relapsed glioblastoma multiforme S De Vleeschouwer, S Fieuws, S Rutkowski, F Van Calenbergh, ... Clinical Cancer Research 14 (10), 3098-3104, 2008 | 345 | 2008 |