| Small CRISPR RNAs guide antiviral defense in prokaryotes SJJ Brouns, MM Jore, M Lundgren, ER Westra, RJH Slijkhuis, ... Science 321 (5891), 960-964, 2008 | 2006 | 2008 |
| Evolution and classification of the CRISPR–Cas systems KS Makarova, DH Haft, R Barrangou, SJJ Brouns, E Charpentier, ... Nature Reviews Microbiology 9 (6), 467-477, 2011 | 1953 | 2011 |
| An updated evolutionary classification of CRISPR–Cas systems KS Makarova, YI Wolf, OS Alkhnbashi, F Costa, SA Shah, SJ Saunders, ... Nature Reviews Microbiology 13 (11), 722-736, 2015 | 1276 | 2015 |
| Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence E Semenova, MM Jore, KA Datsenko, A Semenova, ER Westra, B Wanner, ... Proceedings of the National Academy of Sciences 108 (25), 10098-10103, 2011 | 686 | 2011 |
| CRISPR-based adaptive and heritable immunity in prokaryotes J Van der Oost, MM Jore, ER Westra, M Lundgren, SJJ Brouns Trends in biochemical sciences 34 (8), 401-407, 2009 | 497 | 2009 |
| CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012 | 496 | 2012 |
| Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529, 2011 | 495 | 2011 |
| Structures of the RNA-guided surveillance complex from a bacterial immune system B Wiedenheft, GC Lander, K Zhou, MM Jore, SJJ Brouns, J van der Oost, ... Nature 477 (7365), 486-489, 2011 | 429 | 2011 |
| CRISPR interference directs strand specific spacer acquisition DC Swarts, C Mosterd, MWJ Van Passel, SJJ Brouns PloS one 7 (4), 2012 | 329 | 2012 |
| The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity ER Westra, DC Swarts, RHJ Staals, MM Jore, SJJ Brouns, J van der Oost Annual review of genetics 46, 311-339, 2012 | 290 | 2012 |
| Improving the performance of a quadrupole time-of-flight instrument for macromolecular mass spectrometry RHH van den Heuvel, E van Duijn, H Mazon, SA Synowsky, K Lorenzen, ... Analytical chemistry 78 (21), 7473-7483, 2006 | 232 | 2006 |
| DNA-guided DNA interference by a prokaryotic Argonaute DC Swarts, MM Jore, ER Westra, Y Zhu, JH Janssen, AP Snijders, ... Nature 507 (7491), 258-261, 2014 | 229 | 2014 |
| H‐NS‐mediated repression of CRISPR‐based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO ER Westra, Ü Pul, N Heidrich, MM Jore, M Lundgren, T Stratmann, ... Molecular microbiology 77 (6), 1380-1393, 2010 | 216 | 2010 |
| Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli RN Jackson, SM Golden, PBG van Erp, J Carter, ER Westra, SJJ Brouns, ... Science 345 (6203), 1473-1479, 2014 | 200 | 2014 |
| Degenerate target sites mediate rapid primed CRISPR adaptation PC Fineran, MJH Gerritzen, M Suárez-Diez, T Künne, J Boekhorst, ... Proceedings of the National Academy of Sciences 111 (16), E1629-E1638, 2014 | 192 | 2014 |
| Type IE CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition ER Westra, E Semenova, KA Datsenko, RN Jackson, B Wiedenheft, ... PLoS genetics 9 (9), 2013 | 169 | 2013 |
| Comparative genomic and functional analysis of 100 Lactobacillus rhamnosus strains and their comparison with strain GG FP Douillard, A Ribbera, R Kant, TE Pietilä, HM Järvinen, M Messing, ... PLoS genetics 9 (8), 2013 | 168 | 2013 |
| CRISPR-Cas: Adapting to change SA Jackson, RE McKenzie, RD Fagerlund, SN Kieper, PC Fineran, ... Science 356 (6333), eaal5056, 2017 | 164 | 2017 |
| CRISPRTarget: bioinformatic prediction and analysis of crRNA targets A Biswas, JN Gagnon, SJJ Brouns, PC Fineran, CM Brown RNA biology 10 (5), 817-827, 2013 | 163 | 2013 |
| Clustered regularly interspaced short palindromic repeats (CRISPRs): the hallmark of an ingenious antiviral defense mechanism in prokaryotes S Al-Attar, ER Westra, J Van Der Oost, SJJ Brouns Biological chemistry 392 (4), 277-289, 2011 | 154 | 2011 |
John van der OostMicrobiology, Wageningen UniversityVerified email at wur.nl
