Stan J.J. Brouns

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John van der OostMicrobiology, Wageningen UniversityVerified email at wur.nl
Edze WestraProfessor of Microbiology, University of Exeter, Biosciences, ESIVerified email at exeter.ac.uk
Matthijs JorePostdoctoral Researcher, RadboudumcVerified email at radboudumc.nl
Snijders apThe Francis Crick InstituteVerified email at crick.ac.uk
Franklin L. NobregaLecturer in Microbiology, University of SouthamptonVerified email at soton.ac.uk
Eugene KooninSenior Investigator, NCBI, NIHVerified email at ncbi.nlm.nih.gov
Kira MakarovaNCBI, NIHVerified email at ncbi.nlm.nih.gov
Mark J DickmanProfessor of Bioanalytical Science and Engineering, Dept of Chemical and Biological EngineeringVerified email at sheffield.ac.uk
Tim KünneWageningen University and ResearchVerified email at wur.nl
Raymond StaalsAssistant Professor, Wageningen UniversityVerified email at wur.nl
Willem M de VosProfessor @ Microbiology Wageningen Netherlands @Helsinki FinlandVerified email at wur.nl
Daan C. SwartsAssistant Professor/Personal Investigator | Wageningen University & ResearchVerified email at wur.nl
Konstantin SeverinovVerified email at waksman.rutgers.edu
Blake WiedenheftAssistant Professor Microbiology and Immunology, Montana State UniversityVerified email at montana.edu
Albert J. R. HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center and Utrecht UniversityVerified email at uu.nl
Rebecca E McKenziePostdoctoral Research Fellow, Malaghan Institute of Medical ResearchVerified email at malaghan.org.nz
Peter FineranProfessor, University of Otago, New ZealandVerified email at otago.ac.nz
Ekaterina SemenovaAssistant Research Professor, Waksman Institute, Rutgers University NJVerified email at waksman.rutgers.edu
Sylvain MoineauUniversité LavalVerified email at bcm.ulaval.ca
Daniel HaftStaff Scientist, National Center for Biotechnology Information, NIHVerified email at nih.gov

Stan J.J. Brouns

Associate Professor Molecular Microbiology, Delft University of Technology

Verified email at tudelft.nl - Homepage

CRISPR Bacteriophage Antibiotic resistance


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Small CRISPR RNAs guide antiviral defense in prokaryotes SJJ Brouns, MM Jore, M Lundgren, ER Westra, RJH Slijkhuis, ... Science 321 (5891), 960-964, 2008	2869	2008
Evolution and classification of the CRISPR–Cas systems KS Makarova, DH Haft, R Barrangou, SJJ Brouns, E Charpentier, ... Nature Reviews Microbiology 9 (6), 467-477, 2011	2803	2011
An updated evolutionary classification of CRISPR–Cas systems KS Makarova, YI Wolf, OS Alkhnbashi, F Costa, SA Shah, SJ Saunders, ... Nature Reviews Microbiology 13 (11), 722-736, 2015	2208	2015
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ... Nature Reviews Microbiology 18 (2), 67-83, 2020	895	2020
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence E Semenova, MM Jore, KA Datsenko, A Semenova, ER Westra, B Wanner, ... Proceedings of the National Academy of Sciences 108 (25), 10098-10103, 2011	893	2011
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012	656	2012
CRISPR-based adaptive and heritable immunity in prokaryotes J Van der Oost, MM Jore, ER Westra, M Lundgren, SJJ Brouns Trends in biochemical sciences 34 (8), 401-407, 2009	636	2009
Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529-536, 2011	627	2011
Structures of the RNA-guided surveillance complex from a bacterial immune system B Wiedenheft, GC Lander, K Zhou, MM Jore, SJJ Brouns, J van der Oost, ... Nature 477 (7365), 486-489, 2011	546	2011
CRISPR interference directs strand specific spacer acquisition DC Swarts, C Mosterd, MWJ Van Passel, SJJ Brouns PloS one 7 (4), e35888, 2012	411	2012
DNA-guided DNA interference by a prokaryotic Argonaute DC Swarts, MM Jore, ER Westra, Y Zhu, JH Janssen, AP Snijders, ... Nature 507 (7491), 258-261, 2014	367	2014
The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity ER Westra, DC Swarts, RHJ Staals, MM Jore, SJJ Brouns, J van der Oost Annual review of genetics 46, 311-339, 2012	362	2012
CRISPR-Cas: adapting to change SA Jackson, RE McKenzie, RD Fagerlund, SN Kieper, PC Fineran, ... Science 356 (6333), eaal5056, 2017	302	2017
Improving the performance of a quadrupole time-of-flight instrument for macromolecular mass spectrometry RHH van den Heuvel, E van Duijn, H Mazon, SA Synowsky, K Lorenzen, ... Analytical chemistry 78 (21), 7473-7483, 2006	282	2006
CRISPRTarget: bioinformatic prediction and analysis of crRNA targets A Biswas, JN Gagnon, SJJ Brouns, PC Fineran, CM Brown RNA biology 10 (5), 817-827, 2013	267	2013
Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli RN Jackson, SM Golden, PBG van Erp, J Carter, ER Westra, SJJ Brouns, ... Science 345 (6203), 1473-1479, 2014	265	2014
H‐NS‐mediated repression of CRISPR‐based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO ER Westra, Ü Pul, N Heidrich, MM Jore, M Lundgren, T Stratmann, ... Molecular microbiology 77 (6), 1380-1393, 2010	255	2010
Degenerate target sites mediate rapid primed CRISPR adaptation PC Fineran, MJH Gerritzen, M Suárez-Diez, T Künne, J Boekhorst, ... Proceedings of the National Academy of Sciences 111 (16), E1629-E1638, 2014	254	2014
Type IE CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition ER Westra, E Semenova, KA Datsenko, RN Jackson, B Wiedenheft, ... PLoS genetics 9 (9), e1003742, 2013	241	2013
Targeting mechanisms of tailed bacteriophages FL Nobrega, M Vlot, PA de Jonge, LL Dreesens, HJE Beaumont, ... Nature Reviews Microbiology 16 (12), 760-773, 2018	229	2018

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