Nucleic acids from long-term preserved FFPE tissues are suitable for downstream analyses N Ludyga, B Grünwald, O Azimzadeh, S Englert, H Höfler, S Tapio, ... Virchows Archiv 460, 131-140, 2012 | 225 | 2012 |
GATA6 expression distinguishes classical and basal-like subtypes in advanced pancreatic cancer GM O’Kane, BT Grünwald, GH Jang, M Masoomian, S Picardo, RC Grant, ... Clinical Cancer Research 26 (18), 4901-4910, 2020 | 223 | 2020 |
Spatially confined sub-tumor microenvironments in pancreatic cancer BT Grünwald, A Devisme, G Andrieux, F Vyas, K Aliar, CW McCloskey, ... Cell 184 (22), 5577-5592. e18, 2021 | 216 | 2021 |
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ... Immunity 55 (2), 324-340. e8, 2022 | 210 | 2022 |
Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice B Seubert, B Grünwald, J Kobuch, H Cui, F Schelter, S Schaten, JT Siveke, ... Hepatology 61 (1), 238-248, 2015 | 207 | 2015 |
Recognizing the molecular multifunctionality and interactome of TIMP-1 B Grünwald, B Schoeps, A Krüger Trends in cell biology 29 (1), 6-19, 2019 | 136 | 2019 |
A four-chemokine signature is associated with a T-cell–inflamed phenotype in primary and metastatic pancreatic cancer JM Romero, B Grünwald, GH Jang, PP Bavi, A Jhaveri, M Masoomian, ... Clinical Cancer Research 26 (8), 1997-2010, 2020 | 104 | 2020 |
Pancreatic premalignant lesions secrete tissue inhibitor of metalloproteinases-1, which activates hepatic stellate cells via CD63 signaling to create a premetastatic niche in … B Grünwald, V Harant, S Schaten, M Frühschütz, R Spallek, B Höchst, ... Gastroenterology 151 (5), 1011-1024. e7, 2016 | 104 | 2016 |
Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma S Berchtold, B Grünwald, A Krüger, A Reithmeier, T Hähl, T Cheng, ... Cancer letters 356 (2), 721-732, 2015 | 88 | 2015 |
TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice J Kobuch, H Cui, B Grünwald, P Saftig, PA Knolle, A Krüger Haematologica 100 (8), 1005, 2015 | 57 | 2015 |
Systemic ablation of MMP-9 triggers invasive growth and metastasis of pancreatic cancer via deregulation of IL6 expression in the bone marrow B Grünwald, J Vandooren, M Gerg, K Ahomaa, A Hunger, S Berchtold, ... Molecular Cancer Research 14 (11), 1147-1158, 2016 | 55 | 2016 |
Matrix metalloproteinase-9 (MMP-9) as an activator of nanosystems for targeted drug delivery in pancreatic cancer B Grünwald, J Vandooren, E Locatelli, P Fiten, G Opdenakker, P Proost, ... Journal of Controlled Release 239, 39-48, 2016 | 50 | 2016 |
The induction of human myeloid derived suppressor cells through hepatic stellate cells is dose-dependently inhibited by the tyrosine kinase inhibitors nilotinib, dasatinib and … A Heine, J Schilling, B Grünwald, A Krüger, H Gevensleben, SAE Held, ... Cancer Immunology, Immunotherapy 65, 273-282, 2016 | 45 | 2016 |
Elevated systemic levels of the matrix metalloproteinase inhibitor TIMP-1 correlate with clinical markers of cachexia in patients with chronic pancreatitis and pancreatic cancer O Prokopchuk, B Grünwald, U Nitsche, C Jäger, OL Prokopchuk, ... BMC cancer 18, 1-12, 2018 | 35 | 2018 |
Hes1 controls exocrine cell plasticity and restricts development of pancreatic ductal adenocarcinoma in a mouse model A Hidalgo-Sastre, RL Brodylo, C Lubeseder-Martellato, B Sipos, K Steiger, ... The American journal of pathology 186 (11), 2934-2944, 2016 | 30 | 2016 |
TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer CD Hermann, B Schoeps, C Eckfeld, E Munkhbaatar, L Kniep, ... Journal of Experimental Medicine 218 (11), e20210911, 2021 | 20 | 2021 |
Cellvit: Vision transformers for precise cell segmentation and classification F Hörst, M Rempe, L Heine, C Seibold, J Keyl, G Baldini, S Ugurel, ... Medical Image Analysis 94, 103143, 2024 | 14 | 2024 |
Pancreatic pre-malignant lesions secrete TIMP1, which activates hepatic stellate cells via CD63 signaling to create a pre-metastatic niche in the liver B Grünwald, V Harant, S Schaten, M Fruhschutz, R Spallek, B Hochst Gastroenterology 151 (5), 1011-24, 2016 | 11 | 2016 |
Systemic inflammatory prognostic scores in advanced pancreatic adenocarcinoma LX Ma, Y Wang, O Espin-Garcia, MJ Allen, GH Jang, A Zhang, A Dodd, ... British Journal of Cancer 128 (10), 1916-1921, 2023 | 9 | 2023 |
An engineered paper‐based 3D coculture model of pancreatic cancer to study the impact of tissue architecture and microenvironmental gradients on cell phenotype JL Cadavid, S Latour, F Nowlan, IL Co, N Landon‐Brace, BG Wouters, ... Advanced Healthcare Materials 12 (14), 2201846, 2023 | 8 | 2023 |