| A new evolutionary scenario for the Mycobacterium tuberculosis complex R Brosch, SV Gordon, M Marmiesse, P Brodin, C Buchrieser, K Eiglmeier, ... Proceedings of the national academy of Sciences 99 (6), 3684-3689, 2002 | 1856 | 2002 |
| The diarylquinoline TMC207 for multidrug-resistant tuberculosis AH Diacon, A Pym, M Grobusch, R Patientia, R Rustomjee, L Page-Shipp, ... New England Journal of Medicine 360 (23), 2397-2405, 2009 | 837 | 2009 |
| Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti AS Pym, P Brodin, R Brosch, M Huerre, ST Cole Molecular microbiology 46 (3), 709-717, 2002 | 769 | 2002 |
| Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis AS Pym, P Brodin, L Majlessi, R Brosch, C Demangel, A Williams, ... Nature medicine 9 (5), 533-539, 2003 | 723 | 2003 |
| Multidrug-resistant tuberculosis and culture conversion with bedaquiline AH Diacon, A Pym, MP Grobusch, JM de los Rios, E Gotuzzo, I Vasilyeva, ... New England Journal of Medicine 371 (8), 723-732, 2014 | 514 | 2014 |
| Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis NAJ Gillespie SH1, Crook AM, McHugh TD, Mendel CM, Meredith SK, Murray SR ... New England Journal of Medicine 371 (17), 1577-87, 2014 | 473 | 2014 |
| Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial G Theron, L Zijenah, D Chanda, P Clowes, A Rachow, M Lesosky, W Bara, ... The Lancet 383 (9915), 424-435, 2014 | 431 | 2014 |
| Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug … AH Diacon, PR Donald, A Pym, M Grobusch, RF Patientia, R Mahanyele, ... Antimicrobial agents and chemotherapy 56 (6), 3271-3276, 2012 | 354 | 2012 |
| Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans AS Pym, B Saint-Joanis, ST Cole Infection and immunity 70 (9), 4955-4960, 2002 | 297 | 2002 |
| Genomic deletions classify the Beijing/W strains as a distinct genetic lineage of Mycobacterium tuberculosis AG Tsolaki, S Gagneux, AS Pym, BN Kreiswirth, D Van Soolingen, ... Journal of clinical microbiology 43 (7), 3185-3191, 2005 | 284 | 2005 |
| The evolution of mycobacterial pathogenicity: clues from comparative genomics R Brosch, AS Pym, SV Gordon, ST Cole Trends in microbiology 9 (9), 452-458, 2001 | 275 | 2001 |
| Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis S Gagneux, MV Burgos, K DeRiemer, A Enciso, S Munoz, PC Hopewell, ... PLoS Pathog 2 (6), e61, 2006 | 252 | 2006 |
| Systematic genetic nomenclature for type VII secretion systems W Bitter, ENG Houben, D Bottai, P Brodin, EJ Brown, JS Cox, ... PLoS Pathog 5 (10), e1000507, 2009 | 218 | 2009 |
| Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label … R Dawson, AH Diacon, D Everitt, C van Niekerk, PR Donald, DA Burger, ... The Lancet 385 (9979), 1738-1747, 2015 | 205 | 2015 |
| Bedaquiline in the treatment of multidrug-and extensively drug-resistant tuberculosis AS Pym, AH Diacon, SJ Tang, F Conradie, M Danilovits, C Chuchottaworn, ... European Respiratory Journal 47 (2), 564-574, 2016 | 187 | 2016 |
| Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis A Williams, GJ Hatch, SO Clark, KE Gooch, KA Hatch, GA Hall, K Huygen, ... Tuberculosis 85 (1-2), 29-38, 2005 | 176 | 2005 |
| Evolution of extensively drug-resistant tuberculosis over four decades: whole genome sequencing and dating analysis of Mycobacterium tuberculosis isolates from KwaZulu-Natal KA Cohen, T Abeel, AM McGuire, CA Desjardins, V Munsamy, TP Shea, ... PLoS Med 12 (9), e1001880, 2015 | 172 | 2015 |
| Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study JM Bryant, SR Harris, J Parkhill, R Dawson, AH Diacon, P van Helden, ... The Lancet Respiratory Medicine 1 (10), 786-792, 2013 | 168 | 2013 |
| Regulation of catalase–peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis AS Pym, P Domenech, N Honoré, J Song, V Deretic, ST Cole Molecular microbiology 40 (4), 879-889, 2001 | 160 | 2001 |
| IJMM R Brosch, SV Gordon, A Pym, K Eiglmeier, T Garnier, ST Cole Int. J. Med. Microbiol 290, 143-152, 2000 | 155 | 2000 |
