Wen Chyan
Wen Chyan
PhD Chemistry, Massachusetts Institute or Technology
Verified email at mit.edu
Title
Cited by
Cited by
Year
Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells
W Chyan, DY Zhang, SJ Lippard, RJ Radford
Proceedings of the National Academy of Sciences 111 (1), 143-148, 2014
1182014
Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells
W Chyan, DY Zhang, SJ Lippard, RJ Radford
Proceedings of the National Academy of Sciences 111 (1), 143-148, 2014
1182014
Enzyme-Activated Fluorogenic Probes for Live-Cell and in Vivo Imaging
W Chyan, RT Raines
ACS chemical biology 13 (7), 1810-1823, 2018
722018
Reaction-based probes for imaging mobile zinc in live cells and tissues
ML Zastrow, RJ Radford, W Chyan, CT Anderson, DY Zhang, A Loas, ...
ACS sensors 1 (1), 32-39, 2016
512016
Peptide-based targeting of fluorescent zinc sensors to the plasma membrane of live cells
RJ Radford, W Chyan, SJ Lippard
Chemical science 4 (8), 3080-3084, 2013
432013
Peptide targeting of fluorescein-based sensors to discrete intracellular locales
RJ Radford, W Chyan, SJ Lippard
Chemical science 5 (11), 4512-4516, 2014
162014
Electronic and steric optimization of fluorogenic probes for biomolecular imaging
W Chyan, HR Kilgore, B Gold, RT Raines
The Journal of organic chemistry 82 (8), 4297-4304, 2017
102017
Cytosolic uptake of large monofunctionalized dextrans
W Chyan, HR Kilgore, RT Raines
Bioconjugate chemistry 29 (6), 1942-1949, 2018
92018
Controlled Release Hydrogel Films
RB Timmons, W Chyan, D Bhattacharyya
US Patent App. 12/791,845, 2010
22010
Peptide-based targeting of fluorescent zinc sensors to the plasma membrane of live cells (vol 4, pg 3080, 2013)
RJ Radford, W Chyan, SJ Lippard
CHEMICAL SCIENCE 4 (12), 4532-4532, 2013
12013
Human ribonuclease 1: Endogenous glycosylation, cellular internalization, and cytotoxic capability
V Ressler, H Kilgore, W Chyan, R Raines
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Fluorogenic probes for live-cell imaging of biomolecules
W Chyan
Massachusetts Institute of Technology, 2018
2018
Reaction-based fluorescent probes for detecting zinc
RJ Radford, SJ Lippard, W Chyan
US Patent 9,700,637, 2017
2017
Stereoelectronically Stabilized Flurogenic Probes for Esterase–Activated Biomolecule Imaging
HR Kilgore, W Chyan, B Gold, RT Raines
The FASEB Journal 31, 767.18-767.18, 2017
2017
Targeted sensors for investigating mobile Zinc in biology
W Chyan
Massachusetts Institute of Technology, 2013
2013
Supporting Information for Reaction-Based Probes for Imaging Mobile Zinc in Live Cells and Tissues
ML Zastrow, RJ Radford, W Chyan, CT Anderson, DY Zhang, A Loas, ...
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