guido van mierlo
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MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding
M Perino, G van Mierlo, ID Karemaker, S van Genesen, M Vermeulen, ...
Nature genetics 50 (7), 1002-1010, 2018
Dynamics of gene silencing during X inactivation using allele-specific RNA-seq
H Marks, HHD Kerstens, TS Barakat, E Splinter, RAM Dirks, G van Mierlo, ...
Genome biology 16 (1), 1-20, 2015
The complexity of PRC2 subcomplexes
G van Mierlo, GJC Veenstra, M Vermeulen, H Marks
Trends in cell biology 29 (8), 660-671, 2019
PRC2. 1 and PRC2. 2 synergize to coordinate H3K27 trimethylation
E Healy, M Mucha, E Glancy, DJ Fitzpatrick, E Conway, HK Neikes, ...
Molecular cell 76 (3), 437-452. e6, 2019
Integrative proteomic profiling reveals PRC2-dependent epigenetic crosstalk maintains ground-state pluripotency
G van Mierlo, RAM Dirks, L De Clerck, AB Brinkman, M Huth, SL Kloet, ...
Cell stem cell 24 (1), 123-137. e8, 2019
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma
GL Brien, D Remillard, J Shi, ML Hemming, J Chabon, K Wynne, ...
Elife 7, e41305, 2018
In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states
A Neagu, E van Genderen, I Escudero, L Verwegen, D Kurek, J Lehmann, ...
Nature cell biology 22 (5), 534-545, 2020
Purification and enrichment of specific chromatin loci
M Gauchier, G van Mierlo, M Vermeulen, J Dejardin
Nature methods 17 (4), 380-389, 2020
Two Functional Axes of Feedback-Enforced PRC2 Recruitment in Mouse Embryonic Stem Cells
M Perino, G van Mierlo, C Loh, SMT Wardle, DW Zijlmans, H Marks, ...
Stem cell reports 15 (6), 1287-1300, 2020
Critical role for P53 in regulating the cell cycle of ground state embryonic stem cells
M Ter Huurne, T Peng, G Yi, G van Mierlo, H Marks, HG Stunnenberg
Stem cell reports 14 (2), 175-183, 2020
A Mass Spectrometry Survey of Chromatin‐Associated Proteins in Pluripotency and Early Lineage Commitment
G van Mierlo, RA Wester, H Marks
Proteomics 19 (14), 1900047, 2019
Quantitative subcellular proteomics using SILAC reveals enhanced metabolic buffering in the pluripotent ground state
G van Mierlo, RA Wester, H Marks
Stem cell research 33, 135-145, 2018
Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states
RAM Dirks, G Van Mierlo, HHD Kerstens, AS Bernardo, J Kobolák, I Bock, ...
Epigenetics & chromatin 12 (1), 1-21, 2019
Predicting protein condensate formation using machine learning
G van Mierlo, JRG Jansen, J Wang, I Poser, SJ van Heeringen, ...
Cell Reports 34 (5), 108705, 2021
Chromatin proteomics to study epigenetics–challenges and opportunities
G van Mierlo, M Vermeulen
Molecular & Cellular Proteomics, 100056, 2021
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