| Proteomic quantification of human blood–brain barrier SLC and ABC transporters in healthy individuals and dementia patients ZM Al-Majdoub, H Al Feteisi, B Achour, S Warwood, S Neuhoff, ... Molecular Pharmaceutics 16 (3), 1220-1233, 2019 | 98 | 2019 |
| Quantitative proteomics of clinically relevant drug-metabolizing enzymes and drug transporters and their intercorrelations in the human small intestine N Couto, ZM Al-Majdoub, S Gibson, PJ Davies, B Achour, MD Harwood, ... Drug Metabolism and Disposition 48 (4), 245-254, 2020 | 87 | 2020 |
| Identification and quantification of blood–brain barrier transporters in isolated rat brain microvessels H Al Feteisi, ZM Al‐Majdoub, B Achour, N Couto, A Rostami‐Hodjegan, ... Journal of neurochemistry 146 (6), 670-685, 2018 | 72 | 2018 |
| Quantification of proteins involved in drug metabolism and disposition in the human liver using label-free global proteomics N Couto, ZM Al-Majdoub, B Achour, PC Wright, A Rostami-Hodjegan, ... Molecular Pharmaceutics 16 (2), 632-647, 2019 | 70 | 2019 |
| Liquid biopsy enables quantification of the abundance and interindividual variability of hepatic enzymes and transporters B Achour, ZM Al‐Majdoub, A Grybos‐Gajniak, K Lea, P Kilford, M Zhang, ... Clinical Pharmacology & Therapeutics 109 (1), 222-232, 2021 | 63 | 2021 |
| Quantification of the proteins of the bacterial ribosome using QconCAT technology ZM Al-Majdoub, KM Carroll, SJ Gaskell, J Barber Journal of proteome research 13 (3), 1211-1222, 2014 | 42 | 2014 |
| Non-uniformity of changes in drug-metabolizing enzymes and transporters in liver cirrhosis: implications for drug dosage adjustment E El-Khateeb, B Achour, ZM Al-Majdoub, J Barber, A Rostami-Hodjegan Molecular pharmaceutics 18 (9), 3563-3577, 2021 | 39 | 2021 |
| Quantification of proteins involved in intestinal epithelial handling of xenobiotics ZM Al‐Majdoub, N Couto, B Achour, MD Harwood, G Carlson, G Warhurst, ... Clinical Pharmacology & Therapeutics 109 (4), 1136-1146, 2021 | 28 | 2021 |
| Mass spectrometry‐based abundance atlas of ABC transporters in human liver, gut, kidney, brain and skin ZM Al‐Majdoub, B Achour, N Couto, M Howard, Y Elmorsi, D Scotcher, ... FEBS letters 594 (23), 4134-4150, 2020 | 25 | 2020 |
| Liquid biopsy for patient characterization in cardiovascular disease: verification against markers of cytochrome P450 and P‐glycoprotein activities B Achour, P Gosselin, J Terrier, Y Gloor, ZM Al‐Majdoub, TM Polasek, ... Clinical Pharmacology & Therapeutics 111 (6), 1268-1277, 2022 | 23 | 2022 |
| Data generated by quantitative liquid chromatography-mass spectrometry proteomics are only the start and not the endpoint: optimization of quantitative concatemer-based … B Achour, A Dantonio, M Niosi, JJ Novak, ZM Al-Majdoub, TC Goosen, ... Drug Metabolism and Disposition 46 (6), 805-812, 2018 | 23 | 2018 |
| Quantitative mass spectrometry-based proteomics in the era of model-informed drug development: applications in translational pharmacology and recommendations for best practice E El-Khateeb, AM Vasilogianni, S Alrubia, ZM Al-Majdoub, N Couto, ... Pharmacology & Therapeutics 203, 107397, 2019 | 22 | 2019 |
| Ten years of QconCATs: application of multiplexed quantification to small medically relevant proteomes B Achour, ZM Al-Majdoub, H Al Feteisi, Y Elmorsi, A Rostami-Hodjegan, ... International Journal of Mass Spectrometry 391, 93-104, 2015 | 19 | 2015 |
| Quantitative proteomic map of enzymes and transporters in the human kidney: stepping closer to mechanistic kidney models to define local kinetics ZM Al‐Majdoub, D Scotcher, B Achour, J Barber, A Galetin, ... Clinical Pharmacology & Therapeutics 110 (5), 1389-1400, 2021 | 17 | 2021 |
| Label-free quantitative proteomics and substrate-based mass spectrometry imaging of xenobiotic metabolizing enzymes in ex vivo human skin and a human living skin equivalent model N Couto, JRA Newton, C Russo, E Karunakaran, B Achour, ... Drug Metabolism and Disposition 49 (1), 39-52, 2021 | 17 | 2021 |
| Scaling factors for clearance in adult liver cirrhosis E El-Khateeb, B Achour, D Scotcher, ZM Al-Majdoub, V Athwal, J Barber, ... Drug Metabolism and Disposition 48 (12), 1271-1282, 2020 | 17 | 2020 |
| Proteomics of colorectal cancer liver metastasis: A quantitative focus on drug elimination and pharmacodynamics effects AM Vasilogianni, ZM Al‐Majdoub, B Achour, SA Peters, ... British Journal of Clinical Pharmacology 88 (4), 1811-1823, 2022 | 16 | 2022 |
| Proteomic quantification of changes in abundance of drug-metabolizing enzymes and drug transporters in human liver cirrhosis: different methods, similar outcomes E El-Khateeb, ZM Al-Majdoub, A Rostami-Hodjegan, J Barber, B Achour Drug Metabolism and Disposition 49 (8), 610-618, 2021 | 16 | 2021 |
| In Vitro to In Vivo Extrapolation Linked to Physiologically Based Pharmacokinetic Models for Assessing the Brain Drug Disposition Y Murata, S Neuhoff, A Rostami-Hodjegan, H Takita, ZM Al-Majdoub, ... The AAPS journal 24 (1), 28, 2022 | 13 | 2022 |
| GASP and FASP are Complementary for LC–MS/MS Proteomic Analysis of Drug‐Metabolizing Enzymes and Transporters in Pig Liver M Howard, B Achour, Z Al‐Majdoub, A Rostami‐Hodjegan, J Barber Proteomics 18 (24), 1800200, 2018 | 13 | 2018 |
Amin Rostami-HodjeganProfessor of Systems Pharmacology, University of Manchester, UKGeverifieerd e-mailadres voor manchester.ac.uk
