Follow
Tom Darton
Tom Darton
Verified email at sheffield.ac.uk
Title
Cited by
Cited by
Year
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10269), 99-111, 2021
52162021
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four …
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10277), 881-891, 2021
13102021
Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B. 1.1. 7): an exploratory analysis of a randomised controlled trial
KRW Emary, T Golubchik, PK Aley, CV Ariani, B Angus, S Bibi, B Blane, ...
The Lancet 397 (10282), 1351-1362, 2021
7292021
Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
RECOVERY Collaborative Group, PW Horby, M Mafham, L Peto, ...
Medrxiv, 2021.06. 15.21258542, 2021
648*2021
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
O Abani, A Abbas, F Abbas, M Abbas, S Abbasi, H Abbass, A Abbott, ...
The Lancet 397 (10285), 1637-1645, 2021
572*2021
Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002)
A Flaxman, NG Marchevsky, D Jenkin, J Aboagye, PK Aley, B Angus, ...
The Lancet 398 (10304), 981-990, 2021
2682021
Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a …
ASV Stuart, RH Shaw, X Liu, M Greenland, PK Aley, NJ Andrews, ...
The Lancet 399 (10319), 36-49, 2022
2102022
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis
O Abani, A Abbas, F Abbas, J Abbas, K Abbas, M Abbas, S Abbasi, ...
The Lancet 400 (10349), 359-368, 2022
2082022
An Outpatient, Ambulant-Design, Controlled Human Infection Model Using Escalating Doses of Salmonella Typhi Challenge Delivered in Sodium Bicarbonate …
CS Waddington, TC Darton, C Jones, K Haworth, A Peters, T John, ...
Clinical Infectious Diseases 58 (9), 1230-1240, 2014
1522014
Severity of meningococcal disease associated with genomic bacterial load
T Darton, M Guiver, S Naylor, DL Jack, EB Kaczmarski, R Borrow, ...
Clinical infectious diseases 48 (5), 587-594, 2009
1382009
Design, recruitment, and microbiological considerations in human challenge studies
TC Darton, CJ Blohmke, VS Moorthy, DM Altmann, FG Hayden, ...
The Lancet infectious diseases 15 (7), 840-851, 2015
1372015
Oxford COVID Vaccine Trial Group Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in …
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
Lancet 397 (10269), 99-111, 2021
1332021
Ethics of controlled human infection to address COVID-19
SK Shah, FG Miller, TC Darton, D Duenas, C Emerson, HF Lynch, ...
Science 368 (6493), 832-834, 2020
1272020
Epidemiology and control of tuberculosis in Western European cities
AC Hayward, T Darton, JN Van-Tam, JM Watson, R Coker, V Schwoebel
The international journal of tuberculosis and lung disease 7 (8), 751-757, 2003
972003
Using a human challenge model of infection to measure vaccine efficacy: a randomised, controlled trial comparing the typhoid vaccines M01ZH09 with placebo and Ty21a
TC Darton, C Jones, CJ Blohmke, CS Waddington, L Zhou, A Peters, ...
PLoS neglected tropical diseases 10 (8), e0004926, 2016
842016
Advancing the management and control of typhoid fever: a review of the historical role of human challenge studies
CS Waddington, TC Darton, WE Woodward, B Angus, MM Levine, ...
Journal of Infection 68 (5), 405-418, 2014
742014
The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance …
TC Darton, JE Meiring, S Tonks, MA Khan, F Khanam, M Shakya, ...
BMJ open 7 (6), e016283, 2017
722017
AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific TH1 response with a diverse TCR repertoire
PA Swanson, M Padilla, W Hoyland, K McGlinchey, PA Fields, S Bibi, ...
Science translational medicine 13 (620), eabj7211, 2021
712021
Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model
HC Dobinson, MM Gibani, C Jones, HB Thomaides-Brears, M Voysey, ...
Clinical Infectious Diseases 64 (8), 1066-1073, 2017
682017
Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans
S Fresnay, MA McArthur, L Magder, TC Darton, C Jones, CS Waddington, ...
Journal of translational medicine 14, 1-14, 2016
682016
The system can't perform the operation now. Try again later.
Articles 1–20