Harald H.H.W. Schmidt

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Ulrich Forstermann OR Foerstermann...Professor of Pharmacology, Gutenberg University Mainz Medical CenterVerified email at uni-mainz.de
Jun.-Prof. Dr. Ana I. CasasDepartment of Neurology, University Hospital Essen, Essen, GermanyVerified email at maastrichtuniversity.nl
Johannes-Peter StaschProfessor für Arzneimittelforschung; Chief Scientist Bayer AGVerified email at bayer.com
Timothy D. WarnerProfessor of Vascular InflammationVerified email at qmul.ac.uk
Karin Agnes JandeleitDepartment of Diabetes, Central Clinical School, Monash UniversityVerified email at monash.edu
Christoph KleinschnitzProfessor für NeurologieVerified email at uni-wuerzburg.de
Mark CooperDepartment of Diabetes, Monash UniversityVerified email at monash.edu
Jane A MitchellImperial College LondonVerified email at ic.ac.uk
Stephen P GrayResearch Associate, Kings CollegeVerified email at kcl.ac.uk
Richard WeinbergProfessor of Cell Biology and Physiology, University of North CarolinaVerified email at med.unc.edu
Jan BaumbachUniversity of HamburgVerified email at uni-hamburg.de
Rhian TouyzUniversity of GlasgowVerified email at glasgow.ac.uk
Pietro GhezziUniv Urbino. Emeritus Prof, Brighton & Sussex Med SchoolVerified email at bsms.ac.uk
Ulrich WalterSenior Professor, Centrum für Thrombose und Hämostase, Unversität MainzVerified email at uni-mainz.de
Manuela G. Lopez (Manuela García L...Universidad Autonoma de MadridVerified email at uam.es
Jay JhaDepartment of Diabetes, Monash UniversityVerified email at monash.edu
Martin FeelischUniversity of SouthamptonVerified email at soton.ac.uk
Mahmoud H. ElbatreekLecturer, Faculty of Pharmacy, Zagazig UniversityVerified email at pharmacy.zu.edu.eg
Kathy GriendlingProfessor of Medicine, Emory UniversityVerified email at emory.edu
Hossein Ardeschir GhofraniJustus-Liebig University Giessen, ECCPS, Kerckhoff-Klinik Bad Nauheim, Imperial College LondonVerified email at innere.med.uni-giessen.de

Harald H.H.W. Schmidt

Professor & Chair of Pharmacology and Personalised Medicine, University of Maastricht

Verified email at maastrichtuniversity.nl - Homepage

Systems Medicine Network Pharmacology Drug Repurposing


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NO at work HHHW Schmidt, U Walter Cell 78 (6), 919-925, 1994	2026	1994
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. JS Pollock, U Förstermann, JA Mitchell, TD Warner, HH Schmidt, ... Proceedings of the National Academy of Sciences 88 (23), 10480-10484, 1991	1238	1991
Isoforms of nitric oxide synthase characterization and purification from different cell types U Förstermann, HHHW Schmidt, JS Pollock, H Sheng, JA Mitchell, ... Biochemical pharmacology 42 (10), 1849-1857, 1991	1157	1991
The nitric oxide and cGMP signal transduction system: regulation and mechanism of action HHHW Schmidt, SM Lohmann, U Walter Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1178 (2), 153-175, 1993	1025	1993
NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential OV Evgenov, P Pacher, PM Schmidt, G Haskó, HHHW Schmidt, JP Stasch Nature reviews Drug discovery 5 (9), 755-768, 2006	882	2006
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant S Heumüller, S Wind, E Barbosa-Sicard, HHHW Schmidt, R Busse, ... Hypertension 51 (2), 211-217, 2008	839	2008
Clinical relevance of biomarkers of oxidative stress J Frijhoff, PG Winyard, N Zarkovic, SS Davies, R Stocker, D Cheng, ... Antioxidants & redox signaling 23 (14), 1144-1170, 2015	822	2015
Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells. U Förstermann, JS Pollock, HH Schmidt, M Heller, F Murad Proceedings of the National Academy of Sciences 88 (5), 1788-1792, 1991	784	1991
Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle M Nakane, HHHW Schmidt, JS Pollock, U Förstermann, F Murad FEBS letters 316 (2), 175-180, 1993	732	1993
Mapping of neural nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not with soluble guanylyl cyclase, and novel paraneural functions … HH Schmidt, GD Gagne, M Nakane, JS Pollock, MF Miller, F Murad Journal of Histochemistry & Cytochemistry 40 (10), 1439-1456, 1992	712	1992
Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase RK Ambasta, P Kumar, KK Griendling, HHHW Schmidt, R Busse, ... Journal of Biological Chemistry 279 (44), 45935-45941, 2004	661	2004
Nitric oxide synthase in macula densa regulates glomerular capillary pressure. CS Wilcox, WJ Welch, F Murad, SS Gross, G Taylor, R Levi, HH Schmidt Proceedings of the National Academy of Sciences 89 (24), 11993-11997, 1992	623	1992
Arginine is a physiological precursor of endothelium-derived nitric oxide HHHW Schmidt, H Nau, W Wittfoht, J Gerlach, KE Prescher, MM Klein, ... European journal of pharmacology 154 (2), 213-216, 1988	555	1988
Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase H Schmidt, JS Pollock, M Nakane, LD Gorsky, U Förstermann, F Murad Proc. Natl. Acad. Sci. USA 88 (2), 365-369, 1991	542	1991
Evolution of NADPH oxidase inhibitors: selectivity and mechanisms for target engagement S Altenhöfer, KA Radermacher, PWM Kleikers, K Wingler, HHHW Schmidt Antioxidants & redox signaling 23 (5), 406-427, 2015	540	2015
Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides HHHW Schmidt, TD Warner, K Ishii, H Sheng, FF Murad Science 255 (5045), 721-723, 1992	531	1992
The concise guide to pharmacology 2019/20: Enzymes SPH Alexander, D Fabbro, E Kelly, A Mathie, JA Peters, EL Veale, ... British Journal of Pharmacology 176, S297-S396, 2019	516	2019
Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels JP Stasch, PM Schmidt, PI Nedvetsky, TY Nedvetskaya, AK HS, S Meurer, ... The Journal of clinical investigation 116 (9), 2552-2561, 2006	513	2006
Transcription factor NRF2 as a therapeutic target for chronic diseases: a systems medicine approach A Cuadrado, G Manda, A Hassan, MJ Alcaraz, C Barbas, A Daiber, ... Pharmacological reviews 70 (2), 348-383, 2018	494	2018
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration C Kleinschnitz, H Grund, K Wingler, ME Armitage, E Jones, M Mittal, ... PLoS biology 8 (9), e1000479, 2010	485	2010

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